Quantcast
Channel: Harvard-MIT Health Sciences and Technology - Integrating science, engineering, and medicine to solve problems in human health
Viewing all 961 articles
Browse latest View live

This week in HST - July 10, 2015 - Volume 16, Number 40

$
0
0

HST Community Notices
 

 

Course Information &
Academic Resources

Conferences, Lectures & Seminars
 

Student Opportunities
 

Professional Opportunities
 

Career Programs
 


HST Community Notices

 

CONGRATULATIONS TO THE ANKRUM FAMILY

Congratulations to HST MEMP alum James Ankrum and his family on the arrival of daughter Helena Rose, earlier this month.

 

HST MEMP ALUMNI PROFILES

Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
 

HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

"Step outside your comfort zone. The perspective will surprise you."
 
The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
 
Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
 
 

Course Information & Academic Resources

 
 
HEALTHCARE VENTURES – HST.978/15.367 (FORMERLY 15.S07)
 
Next semester, we are running the fourth year of a class to teach the process of creating new ventures in healthcare.  The class will be an interdisciplinary mix of engineers, scientists, entrepreneurs, and clinicians. Check out the details below and please feel free to email me with any questions! Also – this is now an official HST class – this will be the first year we are offering this course with a designated HST catalog number!
 
What: 15.367/HST.978 Healthcare Ventures: a scientific approach to starting healthcare and medical ventures 
 
When & Where: Tuesdays, 5-8pm; E25-117
 
Who: Anyone passionate about health and medicine (engineers, scientists, business students, and medical students) 
 
How: If you are interested, apply here: http://bit.ly/1eySKq3
 
Why do it: The goal of this class is to take ideas from Design Thinking and from the Lean Startup movement and combine them into a principled approach to starting companies in healthcare.  This approach leverages ideas of experimental design and hypothesis testing in order to accelerate the pace for evaluating and developing ideas and for positioning the idea to establish a new venture.  
 
We have recruited a group of very experienced faculty who, together with their network, will provide extensive mentoring through this process.  In short, this course will provide a supportive, near real-world experience to help you make your mark in the Biomedical arena - or at the very least - provide you with a durable educational experience that will benefit you long beyond your time at MIT.
 
This class is perfect for anyone with a new technology they want to turn into a company, or for anyone with a healthcare challenge in search of the perfect product, or just someone with the passion and energy to learn how to change healthcare.
 
The class will be led by Professor Martha Gray the J.W. Kieckhefer Professor of Health Sciences and Technology and Zen Chu, Senior Lecturer at Sloan, and involves a variety of other faculty from the medical, engineering, and business communities.
 
Please feel free to reach out to the TA Chris Lee (christopher.lee@mit.edu) with any questions. We look forward to seeing you! 
 
 
 
TWO NEW BIOLOGY GRADUATE COURSES IN 2015-2016
 
The  Biology department is offering two new graduate courses in 2015-2016.  
 
The Hallmarks of Cancer (7.85) will be offered in fall 2015 and Protein Folding and Misfolding in Biology (7.87) will be offered in spring 2016.
 
Course descriptions are available here.
 
 
 
REGISTRATION - SUMMER 2015
 
Online Registration for Summer 2015 opens on June 1, 2015. Graduate students who are enrolled in a research degree program and who are taking only thesis or pre-thesis research subjects during the summer will have their registration approved by their departments. All other students should contact their departments to discuss subject selection.
 
Registration must be submitted by the end of the first week of the summer session (Friday, June 12). Registration submitted after this deadline is subject to a $50 late fee.
 
Once the department has approved the registration selections, all subsequent changes to the student's program should be made via the Online Add Drop application.
 
The last day of classes, Friday, August 14, is the deadline for adding and dropping subjects.
 
 
 
 

Conferences, Lectures & Seminars

 

    LEADINGAGE HACKFEST

    LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

    A Youtube video about the event is available here.   
     
    Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

     

    MITES 40TH ANNIVERSARY

    2015 marks the 40th anniversary of the MITES (Minority Introduction to Engineering and Science) program. Join us in celebrating four decades of transformative experiences at MIT for over 2,200 rising high school seniors from across the country.

    Kick-off weekend
     
    On Friday, July 17 and Saturday, July 18, we will launch the MITES 40th anniversary celebration. All people with any affiliation to OEOP are invited to attend, including students, alumni, parents, the MIT community, local community members, donors, and others. More details about the MITES 40th Anniversary Kick-Off Weekend will be made available in June.

     

    PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

    • October 29-30th, 2015 
    • Seaport Hotel & World Trade Center, Boston
    This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
     
    The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
     
    Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
     
    For more information and to register, please visit the Symposium website:

     

    MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

    Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

    But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
     
    At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
     
    More information and events from Medtech Boston is available here.
     
     

    MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

    The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

    Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
     
    Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
     
    Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
     
     

    HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

    The HMS JPNM offers a weekly seminar series from September through May/June.
     
    Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
     
    S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
     
    If you would like to be added to the weekly email distribution list for the lectures, please contact:
    Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
     
    Upcoming Seminars:
     
    Stay tuned for Fall 2015 seminar information.

     
    BRAINMAP SEMINARS

    Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
     
    Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
     
    To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
     
    There are no more Brainmap regular seminars scheduled for the summer.
     
     
     
     

    Student Opportunities

     

    7TH ANNUAL HARVARD VS. MIT CASE COMPETITION

    The Consulting Club at MIT (CCM) and Harvard Graduate Consulting Club (HGCC) cordially invite you to participate in the 7th Annual Harvard vs. MIT Case Competition (August 17-28, 2015)! The Case Competition is an exciting opportunity for non-business Harvard and MIT graduate students and researchers to sharpen their analytical skills, acquire teamwork experience, network with peers and industry professionals, and to address a real-life business challenge. No prior business knowledge or consulting experience is required.

    Prospective participants apply individually, and the organizers will assemble four-person interdisciplinary teams to take on this two-week engagement. Forty (40) Harvard graduate students and researchers will compete with teams from MIT to address a business challenge faced by the client company. All participants will have the opportunity to network with and receive guidance from industry experts and leading consultants. And, teams with top performance will be awarded cash prizes. The MIT vs. Harvard Case Competition is a unique opportunity to explore career paths in business and strategy consulting, as it closely simulates the fast pace and high intensity of consulting projects.
     
    Apply here: http://bit.ly/CaseCompApply.
    Applications are due by 11:59 PM on Monday, July 20, 2015.
    Visit http://bit.ly/HarvardvsMIT for more details about the Case Competition.
     
    ELIGIBILITY CRITERIA
    • Graduate and professional students (non-MBA) at MIT and Harvard, OR
    • Researchers at Harvard, MIT, and affiliated institutions (e.g., hospitals)
    • Interested in business and strategy consulting
    • Active participation throughout the event; must be able to attend ALL FOUR mandatory sessions (see below)
    • Kick-off Event: Monday, August 17, 2PM-6PM, at MIT
    • Consultant Mentoring Session: Friday, August 21, 2PM-5PM, at Harvard
    • Industry Mentoring Session: Monday, August 24, 10AM-5PM, at MIT
    • Semifinal, Final, and Reception: Friday, August 28, 9AM-5PM, at Harvard
    REGISTRATION FEE
     
    A nominal registration fee will be required to confirm participation. Selected participants will be notified by the end of July with further details.
     
    QUESTIONS?
     
    MIT affiliates: contact ccmcasecomp@gmail.com
    Harvard affiliates: contact harvardconsultingclub@gmail.com
     
     

    INTERN: MICROFLUIDIC DEVICE TO HOST MICRO-ORGANS

    The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 

    Project Scope: The position requires a development of a microfluidic device that will host micro-organs such as islets of Langerhans. The student will focus on design and fabrication of the microfluidic device. Multiple iterations will be fabricated and tested for cell compatibility and ease of operation. The student will be trained in design, micro-fabrication, microfluidics, and cell culture. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
     
    Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Experience in at least one CAD package is needed. Previous experience with cell culture, ELISA and microfluidics is desirable. Education: enrolled in an undergraduate program. 
     
    For more information, visit: http://www.karplab.net/.
     
     
    INTERN: MICRONEEDLE BASED ADHESIVE PATCH

    The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 
     
    Project Scope: The position requires a development of a microneedle based adhesive patch based on previous research in the lab (Published: http://dx.doi.org/10.1038/ncomms2715). Microneedles will be fabricated and tested for adhesion on animal tissue ex-vivo. Fabrication process and materials will be optimized to achieve maximal adhesion. Later these patches will be tested in vivo to investigate its efficacy in wound healing. The student will be trained in design, micro-fabrication, mechanical tester and tissue handling. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
     
    Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Background in polymer science is desirable.
     
    For more information, visit: http://www.karplab.net/.

     
    APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

    Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
    For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

     

    UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

    Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
    nomination.
     
    More information may be found here. 
     
     
    GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

    Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

    Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
    community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

    Open positions are as follows:

    • Addir Fellows — MIT Interfaith Dialogue (position open for 2015-16)
    • Data-Visualization: Blacks at MIT History Project (position open for 2015-16)
    • DSL Online Life Learning (position open for 2015-16)
    • Financial Lieracy Fellow (position open for 2015-16)
    • Graduate Accomplishments: Writer (position open for 2015-16)
    • GSC Creative Media Manager (position open for 2015-16)
    • Institute Community and Equity Office (one position open for 2015-16)
    • Language Conversation Excahnge (position open for 2015-16)
    • Programs for women (one position open for 2015-16)
    • Violence Prevention & Response: Programming Development (position open for 2015-16)
    Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
    We are accepting applications now and will fill positions on a rolling basis.
    Receive a monthly stipend while you gain experience.  Apply now!
    Questions? Contact Heather Konar (konar@mit.edu)

     

    COMMUNITY SERVICE WEEKLY BULLETIN

    At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
    Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
     
    As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
    efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
     
    Sign up for the weekly Community Service Bulletin of Events and Programs here.
    News and upcoming events are posted on the homepage.

     

     


    Professional Opportunities

     

    10X GENOMICS - POSITIONS AVAILABLE

    10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

    Applications Scientist: Computational Biology
    10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
     
    Computational Biologist: Algorithm Development
    10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
     
    Computer Scientist: Algorithm Development
    Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
     
    We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

    Data Scientist
    10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
     
    For more information about the company and to see the job listings, visit: 10xgenomics.com/company

    To apply for a position please contact jobs@10xgenomics.com

     

    POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

    GRADUATE STUDENT and/or POSTDOCTORAL ASSOCIATE: contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG), has the potential to provide the first direct evidence for life on Mars and/or on icy moons as well as to enable diverse environmental and clinical applications. Will have an opportunity to develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches; and to design, develop, and validate the instrument in the lab and in the field at terrestrial analogs of Mars or other extreme environments.
    This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. Will work closely with the science PI, Christopher Carr (carrlab.org); the project PI, Maria Zuber, at MIT; the MGH institutional PI, Gary Ruvkun; and other academic and industrial partners.
     
    REQUIREMENTS: a Ph.D. in a relevant field; strong analytical and problem solving skills; and excellent interpersonal, communication, and technical skills.  Seek highly motivated individual with who is able to work independently and contribute to an interdisciplinary team. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills are highly valued.
     
    APPLY: See directions online at http://setg.mit.edu/positions or contact chrisc@mit.edu.

     

    RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

    Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu .

    Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

     

    FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

    Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

    The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

    Responsibilities:

    1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
    2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
    3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
    Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
     
    Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
     
    Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
     
    Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
     
    Availability: Spring 2015 graduates and other recent graduates.
     
    Citizenship: Must be a United States citizen to be eligible for the position.  
     
    Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
     
    Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
     
     

    ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

    Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

    We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

    To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

     

    POSTDOCTORAL FELLOW POSITION - JAIN LAB

    Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
     
    Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
     
    Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
     
     

    IMMUNEERING - POSITIONS AVAILABLE

    Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
     
    This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
     
    Pathway Biology
    Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
     
    Neurodegeneration and CNS Diseases
    Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
     
    Oncology
    Expertise in disease biology and data analysis for cancer research.
     
    Computational Biology
    Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
     
    Next Generation Sequencing (NGS)
    Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
     
    Machine Learning/Statistics (with Biological Applications)
    Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
     
    Responsibilities
    • Develop innovative algorithms and methods for analyzing data to identify biological insights
    • Interpret data from a biological and clinical perspective
    • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
    • Collaborate with colleagues to solve complex computational research problems
    • Present scientific material (written and oral) to diverse audiences
    Minimum Qualifications
    • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
    • Demonstrated experience developing novel algorithms to address complex scientific problems
    • Proven ability to work independently as well as contribute to larger initiatives
    • Effective English communication skills (both written and oral)
    • Proficient in at least one of R, Python, MATLAB, or a similar language.
    • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
    • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
    Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
    • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
    • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
    • Proficient in R
    • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
    For more information, please visit www.immuneering.com
     
    If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

     

    IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

    For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

    Visit IIE online at www.iie.org.
    Please contact the programs directly for additional information or with any questions you may have.
     
    A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

     
     

    Career Programs

     

    ACADEMIA, INDUSTRY OR BOTH PANEL

    Planning your career after MIT? Are you choosing between industry and academia? Come and hear how successful professionals have done it. Both faculty and industry panelists will outline important strategies in career development within industry and academia. They will share their experiences to help you decide whether industry or academia is more attractive for you!
    • Monday, July 20 2015
    • 12:30-2pm
    • 32-123
    Panelists:

    Dr. Mary Gray (Faculty at Indiana University, Media and Anthropology and Senior Researcher, Microsoft Research)
    Dr. Robert Langer (Institute Professor at MIT, Chemical and Biomedical Engineering)
    Dr. Caroline Ross (Associate Head of the Department of Materials Science and Engineering)
    Christopher Nobel (MIT Technology Licensing Officer)

    The panel may have additional representation as well.
    Refreshments provided.
     
    Sponsors: MIT Graduate Student Council, Global Education and Career Development, and the Office of the Vice President for Research 
     
    Registration is requested via CareerBridge: 
     
    Questions? Contact gsc-arc@mit.edu or livngood@mit.edu

     

    PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

    The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
    Dates for the remainder of the 201 Series are listed below:
    • September 22, 2015: Career Paths in Big DataRegister here.
    • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
    • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
     
    MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
     
    Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
     
    Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
     
    Web Presentations 
    We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
     
    2016 Full-time Associate Opportunities 
    Full-time Application Deadline: Applications accepted online now through July 20, 2015 
    Full-time Interviews: August through October 2015 
    Eligibility: Open to PhDs, postdocs, JDs, non-MBA Masters* (all of who are finishing in 2016); open to-medical students/interns/residents/fellows finishing programs in 2016 or 2017
    Online Application Deadline: July 20, 2015 
    *Masters students need to have finished undergraduate education prior to July 2012. If you are a Masters student and finished undergrad after July 2012, please apply as a Business Analyst this upcoming fall. 
     
    MD Fellowship 
    We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
    Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
     
    Diversity & Inclusion at McKinsey 
    At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
     
              

    GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

    For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

    The GECD Event calendar can be found here. 
     
     

    GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

    Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
     
     

    MIT CAREERBRIDGE

    There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

     

    Follow HST on Twitter Follow mit_hst on Twitter

     

     


    Congratulations to the 2015 HST Graduates

    This week in HST - July 24, 2015 - Volume 16, Number 41

    $
    0
    0

    HST Community Notices
     

     

    Course Information &
    Academic Resources

    Conferences, Lectures & Seminars
     

    Student Opportunities
     

    Professional Opportunities
     

    Career Programs
     


    HST Community Notices

     

    HST MEMP ALUMNI PROFILES

    Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
     

    HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

    "Step outside your comfort zone. The perspective will surprise you."
     
    The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
     
    Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
     
     

    Course Information & Academic Resources

     
    HST.583 - FUNCTIONAL MAGNETIC RESONANCE IMAGING: DATA ACQUISITION AND ANALYSIS
     
    This course provides the full background necessary for understanding functional MRI and the instruction on designing and conducting fMRI studies in the human brain, including data acquisition, analysis, and interpretation.
     
    In-depth coverage of the physics of MR signal generation and image encoding, the mechanisms of anatomical and functional contrasts, the physiological basis of the fMRI signals, cerebral hemodynamics, and neurovascular coupling are provided. Basic neuroanatomy, vascular anatomy, and physiology are reviewed.
     
    Design methods for stimulus-, task-driven and resting-state fMRI experiments will be taught; workflows for model-based and data-driven analysis methods for fMRI data are taught. Brain structure analysis and automatic segmentation and registration methods for surface- and region-based analyses of fMRI data are taught.
     
    Guided exploration of special advanced topics including accelerated parallel imaging and Simultaneous Multi-Slice (MultiBand) imaging, ultra-high spatial and temporal resolution imaging, new insights into neurovascular coupling, integrating functional MRI with diffusion MRI data, connectomics, Big Data analysis and machine learning, are offered in discussion sections.
     
    Human subject issues including informed consent, institutional review board requirements and safety in environments with high magnetic field strengths are presented.
     
    Two lectures per week, one laboratory session per week, and one discussion session per week. Laboratory sessions include fMRI data acquisition sessions at the 3 Tesla MRI scanner at MIT and the Connectom and 7 Tesla scanners at the Martinos Center @ MGH, Charlestown, as well as hands-on data analysis workshops.
     
    Assignments include readings of textbook chapters and primary literature as well as fMRI data analysis in the laboratory sessions. Knowledge of basic probability & statistics and linear algebra required; introductory or college-level neurobiology, physics, and signal processing would be helpful.
     
    Course Directors: Susan Whitfield-Gabrieli and Jonathan Polimeni
     
    Laboratory Director: Anastasia Yendiki
     
    Instructors: R. L. Gollub, L. Wald, B. Dickerson, S. Whitfield-Gabrieli, D. Bolar, J. Polimeni, D. Salat, M. Vangel, D. Greve, S. Pujol, D. McLaren, L. Nickerson, J. Augustinack, M. Sabuncu, K. Setsompop, J. Cohen-Adad, S. Ghosh, E. Konukoglu, A. Takahashi, T. Witzel, B. Rosen, A. Yendiki.
     
    For more information, contact Sue Whitfield-Gabrieli, Ph.D. or Jon Polimeni, Ph.D., visit the HST583 Course Website or download the course flyer.
     
     
     
    HEALTHCARE VENTURES – HST.978/15.367 (FORMERLY 15.S07)
     
    Next semester, we are running the fourth year of a class to teach the process of creating new ventures in healthcare.  The class will be an interdisciplinary mix of engineers, scientists, entrepreneurs, and clinicians. Check out the details below and please feel free to email me with any questions! Also – this is now an official HST class – this will be the first year we are offering this course with a designated HST catalog number!
     
    What: 15.367/HST.978 Healthcare Ventures: a scientific approach to starting healthcare and medical ventures 
     
    When & Where: Tuesdays, 5-8pm; E25-117
     
    Who: Anyone passionate about health and medicine (engineers, scientists, business students, and medical students) 
     
    How: If you are interested, apply here: http://bit.ly/1eySKq3
     
    Why do it: The goal of this class is to take ideas from Design Thinking and from the Lean Startup movement and combine them into a principled approach to starting companies in healthcare.  This approach leverages ideas of experimental design and hypothesis testing in order to accelerate the pace for evaluating and developing ideas and for positioning the idea to establish a new venture.  
     
    We have recruited a group of very experienced faculty who, together with their network, will provide extensive mentoring through this process.  In short, this course will provide a supportive, near real-world experience to help you make your mark in the Biomedical arena - or at the very least - provide you with a durable educational experience that will benefit you long beyond your time at MIT.
     
    This class is perfect for anyone with a new technology they want to turn into a company, or for anyone with a healthcare challenge in search of the perfect product, or just someone with the passion and energy to learn how to change healthcare.
     
    The class will be led by Professor Martha Gray the J.W. Kieckhefer Professor of Health Sciences and Technology and Zen Chu, Senior Lecturer at Sloan, and involves a variety of other faculty from the medical, engineering, and business communities.
     
    Please feel free to reach out to the TA Chris Lee (christopher.lee@mit.edu) with any questions. We look forward to seeing you! 
     
     
     
    TWO NEW BIOLOGY GRADUATE COURSES IN 2015-2016
     
    The  Biology department is offering two new graduate courses in 2015-2016.  
     
    The Hallmarks of Cancer (7.85) will be offered in fall 2015 and Protein Folding and Misfolding in Biology (7.87) will be offered in spring 2016.
     
    Course descriptions are available here.
     
     
     
    REGISTRATION - SUMMER 2015
     
    Online Registration for Summer 2015 opens on June 1, 2015. Graduate students who are enrolled in a research degree program and who are taking only thesis or pre-thesis research subjects during the summer will have their registration approved by their departments. All other students should contact their departments to discuss subject selection.
     
    Registration must be submitted by the end of the first week of the summer session (Friday, June 12). Registration submitted after this deadline is subject to a $50 late fee.
     
    Once the department has approved the registration selections, all subsequent changes to the student's program should be made via the Online Add Drop application.
     
    The last day of classes, Friday, August 14, is the deadline for adding and dropping subjects.
     
     
     
     

    Conferences, Lectures & Seminars

     

      LEADINGAGE HACKFEST

      LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

      A Youtube video about the event is available here.   
       
      Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

       

      PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

      • October 29-30th, 2015 
      • Seaport Hotel & World Trade Center, Boston
      This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
       
      The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
       
      Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
       
      For more information and to register, please visit the Symposium website:

       

      MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

      Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

      But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
       
      At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
       
      More information and events from Medtech Boston is available here.
       
       

      MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

      The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

      Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
       
      Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
       
      Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
       
       

      HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

      The HMS JPNM offers a weekly seminar series from September through May/June.
       
      Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
       
      S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
       
      If you would like to be added to the weekly email distribution list for the lectures, please contact:
      Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
       
      Upcoming Seminars:
       
      Stay tuned for Fall 2015 seminar information.

       
      BRAINMAP SEMINARS

      Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
       
      Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
       
      To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
       
      There are no more Brainmap regular seminars scheduled for the summer.
       
       
       
       

      Student Opportunities
       

      KOCH INSTITUTE GRADUATE STUDENT FELLOWSHIPS

      The Koch Institute for Integrative Cancer Research is now soliciting proposals for several fellowships for graduate student support for Academic Year 2015/2016. Each source of funding has an emphasis on students working in the broad area of cancer research. Funds are available in the following categories:

      1.Seven (7) fellowships are available through Koch, Ludwig and other endowed funds for School of Science graduate students working in cancer research.

      2.One (1) fellowship is available through blended Koch Institute funds for an MIT graduate student working in cancer research.
       
      3.Three (3) fellowships are available through the Ludwig Research Funds in support of MIT graduate students with metastasis as their research focuses.
       
      Awards will fund academic year stipend (9-Months at the standard School of Science/Engineering stipend rate), medical insurance and tuition for each successful candidate.
       
      Selection criteria include demonstrated progress and accomplishments, cancer relevance and potential of student to realize the goals of the project. Preference will be given to students in the later years of their PhD research.
       
      The application should be written by the student and should make clear the relevance of the work to cancer research.  To be included:
      • Paper applications (three copies) should consist of:
        • Cover page with applicant name, MIT Academic Program and year of study, title of project, faculty supervisor and which of the categories of funding that you are applying for. Please also note if you have received previous fellowships from the KI.
        • Curriculum vitae.
        • 3 page (maximum) outline of student's research progress to date and plans for continuation of the thesis research.
        • One letter of recommendation is required. The letter should be from the student's faculty advisor and should summarize prior and current mechanisms for support. Letters may be mailed directly from the PI to Lori Spindler, 76-158,  (lorispin@mit.edu) or may be sealed in an envelope and included with the application.
      Applications must be received (Attn: Lori Spindler) by August 10, 2015 - no later than noon. No extensions will be granted and incomplete submittals will not be reviewed. 
       
      A faculty committee will review all applications and awards will be made effective September 1, 2015.
       
      NOTE: While there is no limit on the number of applications from an individual laboratory, it is not typical that more than one application from a laboratory would be funded.
       
       

      INTERN: MICROFLUIDIC DEVICE TO HOST MICRO-ORGANS

      The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 

      Project Scope: The position requires a development of a microfluidic device that will host micro-organs such as islets of Langerhans. The student will focus on design and fabrication of the microfluidic device. Multiple iterations will be fabricated and tested for cell compatibility and ease of operation. The student will be trained in design, micro-fabrication, microfluidics, and cell culture. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
       
      Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Experience in at least one CAD package is needed. Previous experience with cell culture, ELISA and microfluidics is desirable. Education: enrolled in an undergraduate program. 
       
      For more information, visit: http://www.karplab.net/.
       
       
      INTERN: MICRONEEDLE BASED ADHESIVE PATCH

      The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 
       
      Project Scope: The position requires a development of a microneedle based adhesive patch based on previous research in the lab (Published: http://dx.doi.org/10.1038/ncomms2715). Microneedles will be fabricated and tested for adhesion on animal tissue ex-vivo. Fabrication process and materials will be optimized to achieve maximal adhesion. Later these patches will be tested in vivo to investigate its efficacy in wound healing. The student will be trained in design, micro-fabrication, mechanical tester and tissue handling. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
       
      Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Background in polymer science is desirable.
       
      For more information, visit: http://www.karplab.net/.

       
      APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

      Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
      For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

       

      UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

      Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
      nomination.
       
      More information may be found here. 
       
       
      GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

      Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

      Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
      community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

      Open positions are as follows:

      • Addir Fellows — MIT Interfaith Dialogue (position open for 2015-16)
      • Data-Visualization: Blacks at MIT History Project (position open for 2015-16)
      • DSL Online Life Learning (position open for 2015-16)
      • Financial Lieracy Fellow (position open for 2015-16)
      • Graduate Accomplishments: Writer (position open for 2015-16)
      • GSC Creative Media Manager (position open for 2015-16)
      • Institute Community and Equity Office (one position open for 2015-16)
      • Language Conversation Excahnge (position open for 2015-16)
      • Programs for women (one position open for 2015-16)
      • Violence Prevention & Response: Programming Development (position open for 2015-16)
      Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
      We are accepting applications now and will fill positions on a rolling basis.
      Receive a monthly stipend while you gain experience.  Apply now!
      Questions? Contact Heather Konar (konar@mit.edu)

       

      COMMUNITY SERVICE WEEKLY BULLETIN

      At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
      Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
       
      As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
      efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
       
      Sign up for the weekly Community Service Bulletin of Events and Programs here.
      News and upcoming events are posted on the homepage.

       

       


      Professional Opportunities

       

      PORTAL INSTRUMENTS POSITION AVAILABLE

      Lead Firmware Engineer

      About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
       
      Working at Portal Instruments:
      • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
      • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
      • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
      Role and Responsibilities:
      • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
      • Design, build, debug, and optimize the device’s firmware
      • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
      • Integrate with a team of firmware, software, and control engineers.
      • Design, build, debug, and optimize firmware
      • Evaluate system performance by designing, executing, and documenting experimental plans.
      • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
      • Support electrical compliance testing.
      • Support the manufacture and testing of electronic assemblies by providing test procedures
      • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
      Required Skills and Experience:
      • Development of efficient microcontroller firmware in C, preferably ARM.
      • Familiarity with quality system requirements for medical software system development.
      • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
      • Experience with high-bandwidth motion control.
      • Sensor synthesis / sensor fusion.
      • Familiarity with electronic hardware design.
      • Automated integration testing of firmware.
      Qualifications:
      • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
      • 5+ years of experience in commercial development and/or validation.
      • Experience with medical products development and FDA or related product approvals a plus.
      • Outstanding software engineering and design skills.
      • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
      • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
      • Ability to work independently in a start-up environment.
      Salary commensurate with experience; potential equity participation.
       
      To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
       

       

      10X GENOMICS - POSITIONS AVAILABLE

      10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

      Applications Scientist: Computational Biology
      10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
       
      Computational Biologist: Algorithm Development
      10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
       
      Computer Scientist: Algorithm Development
      Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
       
      We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

      Data Scientist
      10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
       
      For more information about the company and to see the job listings, visit: 10xgenomics.com/company

      To apply for a position please contact jobs@10xgenomics.com

       

      POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

      GRADUATE STUDENT and/or POSTDOCTORAL ASSOCIATE: contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG), has the potential to provide the first direct evidence for life on Mars and/or on icy moons as well as to enable diverse environmental and clinical applications. Will have an opportunity to develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches; and to design, develop, and validate the instrument in the lab and in the field at terrestrial analogs of Mars or other extreme environments.
      This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. Will work closely with the science PI, Christopher Carr (carrlab.org); the project PI, Maria Zuber, at MIT; the MGH institutional PI, Gary Ruvkun; and other academic and industrial partners.
       
      REQUIREMENTS: a Ph.D. in a relevant field; strong analytical and problem solving skills; and excellent interpersonal, communication, and technical skills.  Seek highly motivated individual with who is able to work independently and contribute to an interdisciplinary team. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills are highly valued.
       
      APPLY: See directions online at http://setg.mit.edu/positions or contact chrisc@mit.edu.

       

      RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

      Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu .

      Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

       

      FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

      Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

      The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

      Responsibilities:

      1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
      2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
      3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
      Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
       
      Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
       
      Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
       
      Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
       
      Availability: Spring 2015 graduates and other recent graduates.
       
      Citizenship: Must be a United States citizen to be eligible for the position.  
       
      Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
       
      Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
       
       

      ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

      Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

      We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

      To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

       

      POSTDOCTORAL FELLOW POSITION - JAIN LAB

      Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
       
      Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
       
      Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
       
       

      IMMUNEERING - POSITIONS AVAILABLE

      Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
       
      This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
       
      Pathway Biology
      Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
       
      Neurodegeneration and CNS Diseases
      Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
       
      Oncology
      Expertise in disease biology and data analysis for cancer research.
       
      Computational Biology
      Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
       
      Next Generation Sequencing (NGS)
      Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
       
      Machine Learning/Statistics (with Biological Applications)
      Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
       
      Responsibilities
      • Develop innovative algorithms and methods for analyzing data to identify biological insights
      • Interpret data from a biological and clinical perspective
      • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
      • Collaborate with colleagues to solve complex computational research problems
      • Present scientific material (written and oral) to diverse audiences
      Minimum Qualifications
      • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
      • Demonstrated experience developing novel algorithms to address complex scientific problems
      • Proven ability to work independently as well as contribute to larger initiatives
      • Effective English communication skills (both written and oral)
      • Proficient in at least one of R, Python, MATLAB, or a similar language.
      • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
      • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
      Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
      • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
      • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
      • Proficient in R
      • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
      For more information, please visit www.immuneering.com
       
      If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

       

      IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

      For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

      Visit IIE online at www.iie.org.
      Please contact the programs directly for additional information or with any questions you may have.
       
      A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

       
       

      Career Programs

       

      PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

      The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
      Dates for the remainder of the 201 Series are listed below:
      • September 22, 2015: Career Paths in Big DataRegister here.
      • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
      • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
       
      MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
       
      Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
       
      Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
       
      Web Presentations 
      We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
       
      MD Fellowship 
      We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
      Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
       
      Diversity & Inclusion at McKinsey 
      At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
       
                

      GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

      For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

      The GECD Event calendar can be found here. 
       
       

      GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

      Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
       
       

      MIT CAREERBRIDGE

      There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

       

      Follow HST on Twitter Follow mit_hst on Twitter

       

       

      Faculty Poster Session

      $
      0
      0

      Please join the HST community at its annual Faculty Poster Session featuring posters from PI's across MIT, HMS, and area hospitals.

      Thursday, September 24, 2015
      5 - 7 PM

      TMEC Atrium
      Harvard Medical School
      260 Longwood Ave, 2nd Floor
      Boston, MA

      Participation is limited to the first 50 posters registered. Registration closes Thursday, September 17 at 5 pm. Please contact hst-postersession@mit.edu with any questions.

      Poster

      Your poster may take any form in a 4’ x 4’ format, ranging from an overview of your entire research portfolio to sample results of a recent research project.

      Parking

      If you request parking below, we will arrange parking at the NRB Garage Lot located at 77 Avenue Louis Pasteur, Boston, MA. When you arrive please submit your name to the attendant for a parking pass. Keep the voucher on your person as you will need it to access the lot after the event.

      Poster Set Up

      Presenters should plan to arrive 15 minutes early for set up. Please stop by the registration desk for your name tag and poster location.

      Registration

      If your lab is presenting multiple posters at this event, please register each poster separately.
      PI Information
      If preferred, please enter the name and email of an administrative assistant.
      Please register information about other presenters for this poster below.
      Presenter No. 1
      Postdoc, HST MEMP student, HST MD student, etc.
      Presenter No. 2
      Postdoc, HST MEMP student, HST MD student, etc.
      Presenter No. 3
      Postdoc, HST MEMP student, HST MD student, etc.

      How do you hack health care?

      $
      0
      0
      Monday, July 20, 2015

       

      A TEAM FROM GRAND HACK 2015, AN MIT HACKING MEDICINE EVENT HELD AT THE MIT MEDIA LAB IN APRIL. PHOTO COURTESY OF MIT HACKING MEDICINE.

      MIT doesn’t have a medical school, so it might seem unusual that so many students, researchers, and alumni are making a real-world impact in health care and medicine. But those two fields are rapidly evolving, and the need for MIT’s mindset of technology-focused solutions has never been greater.

      “MIT is kind of like Switzerland — it’s neutral ground,” says Lina Colucci, a PhD candidate in the Harvard-MIT Health Sciences and Technology Program. “You can’t get a medical degree from MIT, but it’s filled with designers, developers, and engineers. And everyone in the medical community wants to work with all of these brilliant people.”

      Colucci is a co-director of MIT Hacking Medicine, a student-run group that bring together innovative thinkers to rethink and solve healthcare’s most pervasive problems.

      “Hacking is such a core part of the MIT culture,” says co-director Priya Garg ’15. “Our methodology is to disrupt the silos that are prevalent in healthcare by applying MIT’s hacking ethos to create innovations.”

      Hacking Medicine’s main silo disruptor is Health Hackathons, weekend-long events that attract about 400 doctors, nurses, researchers, and designers who tackle solutions to shared healthcare issues. The first hackathon took place at MIT 2011, and since that time, more than 20 events have taken place across four continents.

      “It’s design thinking for healthcare,” says Colucci. “We look at it from all perspectives — clinical, technological, design, and business. It’s asking, ‘How can you create a spark that gets lots of different people thinking together?’”

      During the hackathons, strangers-turned-collaborators share ideas in pitch sessions, then turn to other participants for ideas and advice. According to Colucci, more than a dozen startups have been created as a results of the events.

      “The healthcare industry is kind of seen as an industry that doesn’t keep up with technology and innovation,” Colucci says. “But that’s changing — all major hospitals have innovation centers now. They want to incorporate new methods and they’re working with us to do it.”

      According to the Hacking Medicine database on its website, 10 hackathons have already been held in 2015 in major cities such as Berlin, Paris, and Stockholm, and in smaller cities such as Missoula, Montana, and Halifax, Nova Scotia. The next event, which will focus on elderly health, is scheduled for July 25 in Singapore.

      Hacking Medicine has been so successful that plans are in place for the program to be spun out as a non-profit independent entity led in part by MIT Sloan School of Management senior lecturer Zen Chu. According to The Wall Street Journal, the program will form its first working groups in early October.

      Jay London | MIT Alumni Association

      http://newsoffice.mit.edu/2015/how-do-you-hack-health-care-use-design-thinking-0720

      MEMP PhD Student Or Gadish and HST GEMS/MechE PhD student Steven Keating Awarded Hugh Hampton Young Fellowships

      $
      0
      0
      Tuesday, July 28, 2015

      Named for the pioneering medical researcher, the Hugh Hampton Young Fellowship is one of the Office of the Dean for Graduate Education’s (ODGE) most prestigious awards. A famed urologist, Young was not only an innovator in medical science, his curiosity and intellectual drive also stirred him in other endeavors such as civic enhancement, the arts, and the burgeoning field of aviation.  Accordingly, the goal of the Hugh Hampton Young Fellowship is to not only recognize academic achievement, but also exceptional personal and character strengths, with heavy emphasis on the perceived overall potential of the candidate to have a positive impact on humanity.

      Established in 1965 through an anonymous donor, roughly 150 students have benefited from this award over the last 50 years. “The Hugh Hampton Young Fellowship has always been handled slightly differently than our other opportunities,” says ODGE Manager of Graduate Fellowships Scott Tirrell. “As a stipulation of the award, recipients are chosen by an external selection committee largely comprised of former Hugh Hampton Young Fellowship recipients. Through careful evaluation of candidate application material and personal interviews, the committee seeks individuals exhibiting a blend of broad focus, leadership, and initiative.”

      The committee has selected seven new recipients as the 2015-16 fellowship cohort. They will join a legacy of exceptional individuals, and will hopefully go on to make positive impacts on society in the tradition of Young himself. (Accomplishments of former Hugh Hampton Young Fellowship recipients can be seen on the ODGE website.)

      The 2015 Young Fellows: (clockwise from top left) John Arroyo, Or Gadish, Steven Keating, Iris Zielski, Mitali Thakor, William Li, and Georgia Lagoudas

      John Arroyo is a PhD student in the Department of Urban Studies and Planning. He received his master’s in city planning and a certificate in urban design from MIT and a BA in public relations, with a concentration in planning and development, from the University of Southern California. His professional career includes community development, housing, and arts and cultural programming experience with various nonprofits, foundations, and government agencies. Prior to MIT he was an Executive Fellow at the Coro Foundation’s Southern California Center for Civic Leadership. Arroyo is interested in the interrelationship between the built environment, migration, and policy. In particular, his comparative research investigates how the public-built environment influences and reshapes sociocultural behavior among transnational Latino migrants, and how local urban planning and design policies react to this adjustment phenomenon in both U.S. receiving communities and native Latin American sending communities (Mexico and Central America). In 2012 he co-created Project 51’s "Play the L.A. River," a public humanities project dedicated to increasing awareness of and access to the Los Angeles River as a civic space.

      Or Gadish is a PhD candidate in Health Sciences and Technology at MIT’s Institute for Medical Engineering and Science. His thesis work seeks to combine the advances of vascular biology, biomaterials and tissue engineering, and cancer biology to better understand the relationship between cancer cells and tumor-resident endothelial cells (EC), the cells that line all blood vessels. While healthy ECs are anti-tumorigenic, tumors transform ECs into a pro-tumorigenic state. As such, Gadish is also looking closely at the relationship between tumor-transformed ECs and their healthy brethren, which can be grown in vitro, embedded on biomaterial scaffolds, and implanted next to tumors to both inhibit cancer cell processes and rescue transformed ECs.

      Steven Keating is a PhD candidate in the Department of Mechanical Engineering focused on novel platforms for additive manufacturing, synthetic biology, and designed growth. Based out of the Mediated Matter group at the MIT Media Lab, his research covers a diverse range including building-scale 3-D printing, microfluidic digital fabrication, and open patient data access. From gears to genomes, he is interested in exploring new design possibilities. Keating has lectured and helped instruct for several MIT design courses — including 2.00b (Toy Product Design), 2.009 (Product Engineering Processes), MAS.500 (Hands on Foundations in Media Technology), and MAS.S64 (Special Subject in Media Technology) — and is a patient advocate for open health data. Calgary is his hometown and he is invigorated by curiosity, creativity, and maple syrup.

      Georgia Lagoudas is a PhD candidate in the Department of Biological Engineering. She completed her undergraduate degree at Rice University in bioengineering. She is interested in investigating the microbes inside of our bodies — in particular our lungs — and how these microbes are associated with health. We have only recently discovered that bacteria exist in the healthy lungs, but we do not have a clear understanding of their role. Lagoudas is focused on using mice as a model system to study the dynamics of the lung microbial population and investigate how changes in the immune system or health status might alter these microbes.

      William Li is a PhD candidate in the Department of Electrical Engineering and Computer Science focused on data science on open government datasets. He develops and applies methods to analyze and visualize large collections of text documents to answer research questions in computational social science and promote public understanding of law, politics, and public policy. Li's recent work includes predicting the authors of unsigned Supreme Court opinions, quantifying repeated text in Congress, and measuring the complexity of our laws using language and software engineering metrics. Along with these research interests, Li helps run the MIT Assistive Technology Club and co-taught 6.811 (Principles and Practice of Assistive Technology) in 2014, a full-semester course that focuses on accessibility and assistive technologies for people with disabilities. 

      Mitali Thakor, a continuing Hugh Hampton Young Fellow, is a PhD candidate in the MIT Program in History, Anthropology, and Science, Technology, and Society. Her dissertation uses feminist anthropological methods to explore the global carceral politics of anti-trafficking, pornography, and child exploitation in the context of emerging digital technologies. She has conducted fieldwork in the U.S., Netherlands, and Thailand, and hopes that her research will inform critical and comprehensive practices to reduce exploitation and victimization. Outside of research, Mitali is a campus peer educator and organizer on issues of sexual violence and healthy relationships, and is also active with local anti-racist and queer feminist political organizations. Prior to MIT, Mitali worked on community sexual health research in the Philippines, and also holds BA degrees in feminist studies and anthropology from Stanford University.

      Iris Zielske is an MS and MBA candidate in the Leaders for Global Operations program. She holds a BS in industrial and systems engineering and a BA in linguists from the University of Florida. As a part of her studies at MIT she has worked with LV Prasad Eye Institute on a designing a prototype for a wearable, electronic device for students with low vision in India and worked with Gradian Health Systems on evaluating their after-sales service strategy for anesthesia machines in East Africa. Her thesis research focuses on digital identification systems for biotechnology supply chains.

      Office of the Dean for Graduate Education

      http://newsoffice.mit.edu/2015/hugh-hampton-young-fellowship-celebrates-50-years-0529

      Podcast Featuring HST Alumni David Goodman and David Shaywitz

      $
      0
      0
      Tuesday, July 28, 2015

      David Goodman (MD ’93) and David Shaywitz (PhD ’97, MD ’99)—former anatomy lab partners—reminisce about their time as HST students, among other things.

      After his second series of medical school rejections, biomedical engineer David Goodman found his way to a nascent medical device company seeking to develop an easy way to measure oxygen levels in the blood. The result—the Nellcor pulse oximeter—transformed medical care. It also earned David a coveted spot in the Health Science Technology (HST) program at Harvard Medical School, and launched him on a storied career of healthcare entrepreneurship. And motorcycle ridership.

      David playing doctor

       

      Join David Shaywitz and I as we talk with the other David about his journey, his influences, his companies, including his newest venture, Feet First, and hear how the son of a Westchester dentist—this one not named Zuckerberg—made a name for himself in Silicon Valley. 

      Click here to listen to the podcast: http://venturevalkyrie.com/new-tech-tonics-podcast-david-goodman-roars-into-town/

      Lisa Suennen | Venture Valkyrie

       

       

      MIT follows Monday Schedule of Classes

      $
      0
      0
      Date and Time: 
      Tuesday, October 13, 2015 (All day)
      Location: 

      MIT classes only


      This week in HST - August 7, 2015 - Volume 16, Number 42

      $
      0
      0

      HST Community Notices
       

       

      Course Information &
      Academic Resources

      Conferences, Lectures & Seminars
       

      Student Opportunities
       

      Professional Opportunities
       

      Career Programs
       


      HST Community Notices

       

      KENNETH RAININ FOUNDATION INNOVATIONS SYMPOSIUM POSTER AWARDS

      MEMP PhD candidate, Ben Mead and his team from Jeff Karp's lab took home two poster prizes (of four awarded)  at the prestigious Kenneth Rainin Foundation Innovations Symposium: Wound Healing, Repair and IBD, held in San Francisco on July 20-21, 2015. More information on the symposium and the posters can be found here.

      Congratulations to Ben and team and Jeff!
       

      HST BBQ ON THE QUADRANGLE AT HMS

      • Wednesday, August 26, 2015
      • 4:30-7:30pm
      • HMS Quadrangle, Longwood Ave., Boston
      Music!  Food!  Beverages!  Good Company!
       
      More details, and a request for RSVPs, will be coming in August.  
      Enjoy the summer!

       

      IMES DISTINGUISHED SPEAKER SERIES

      The IMES Distinguished Speaker Series invites you to attend a lecture by Dr. Helen Mayberg.
       
      "Targeted Therapeutic Modulation of Depression Circuits using Deep Brain Stimulation" 
      • Thursday, September 17, 2015
      • 4:30pm
      • E25-111
      Helen Mayberg, M.D. is Professor of Psychiatry, Neurology and Radiology and the Dorothy Fuqua Chair in Psychiatric Neuroimaging and Therapeutics at Emory University.  Over the last 25 years, her multi-disciplinary depression research team has worked to integrate cutting-edge imaging strategies, quantitative behavioral and psychophysiological metrics, and experimental treatment trials to define brain-based biomarkers that can optimize treatment selection for individual patients.  This work was foundational for the first studies of subcallosal cingulate deep brain stimulation for treatment resistant depression and remains the cornerstone of current studies to both refine and optimize DBS implementation and characterize network mechanisms mediating its antidepressant effects. Dr. Mayberg is a neurologist, trained at Columbia's Neurological Institute in New York, with fellowship training in nuclear medicine at Johns Hopkins. She is a member of the Institute of Medicine, among other honors, and participates in a wide variety of advisory and scientific activities across multiple fields in neuroscience.  
       
      Abstract:
      Deep Brain Stimulation is an emerging treatment strategy for patients with intractable depression with imaging playing a crucial role in the development, testing and refinement of the procedure. Multimodal modeling of structural and functional connections combined with real-time behavioral, autonomic and electrophysiological metrics are now used to more precisely identify the optimal target location as well as track long-term stimulation effects. Together these studies offer a unique perspective on critical pathways and mechanisms mediating antidepressant effects of DBS, and on the pathophysiology of treatment resistant depression more generally. 
       

      HST MEMP ALUMNI PROFILES

      Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
       

      HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

      "Step outside your comfort zone. The perspective will surprise you."
       
      The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
       
      Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
       
       

      Course Information & Academic Resources

       
       
      10.807/15.371 INNOVATION TEAMS (“I-TEAMS”)
      • Wednesdays 4:30-7pm & Fridays 9-10:30am
      • 32-124
      • 12 units
      Instructors: Dr. Luis Perez-Breva (School of Engineering), Dr. Noubar Afeyan (Flagship Ventures & MIT Sloan), Prof. Fiona Murray (MIT Sloan & Trust Center for Entrepreneurship)
       
      “Innovation Teams is the class that transforms MIT technologies to ones that can impact the world.”
       
      Course Description:

      i-Teams is a graduate course offered jointly between the Schools of Engineering and Management. Students choose from a set of recent breakthrough technologies selected by the Class Faculty from MIT labs on the basis of their excitement and commercial potential.  Working in cross-disciplinary teams of 3-5 class peers plus an industry “catalyst”, students focus throughout the semester on exploring a commercialization strategy for their technology and developing a final recommendation for the next steps and the best vehicle to bring the project to impact (e.g. startup, license, NGO).

       
      Course Objectives:
      • Synthesize opportunities for innovation by iterating between technology and the market
      • Identify and leverage resources in an innovation ecosystem
      • Create an actionable go-to-market plan
      • Work with peers from different disciplines
      Course Composition:
       
      Approximately 50% of students are from the Sloan School and 50% are Graduate Students from the Schools of Engineering, Science, Architecture and HASS.   No experience is necessary.  Successful students come with an interest in innovation and a readiness to engage in the innovation process.  Advanced undergrads may take the class with instructor approval.
       
      Enrollment is limited.  Priority will be given to students who apply early.  Please visit the i-Teams website at http://iteams.mit.edu for application and registration details or email iTeams-TA@mit.edu with any questions.
       
       
      HST.583 - FUNCTIONAL MAGNETIC RESONANCE IMAGING: DATA ACQUISITION AND ANALYSIS
       
      This course provides the full background necessary for understanding functional MRI and the instruction on designing and conducting fMRI studies in the human brain, including data acquisition, analysis, and interpretation.
       
      In-depth coverage of the physics of MR signal generation and image encoding, the mechanisms of anatomical and functional contrasts, the physiological basis of the fMRI signals, cerebral hemodynamics, and neurovascular coupling are provided. Basic neuroanatomy, vascular anatomy, and physiology are reviewed.
       
      Design methods for stimulus-, task-driven and resting-state fMRI experiments will be taught; workflows for model-based and data-driven analysis methods for fMRI data are taught. Brain structure analysis and automatic segmentation and registration methods for surface- and region-based analyses of fMRI data are taught.
       
      Guided exploration of special advanced topics including accelerated parallel imaging and Simultaneous Multi-Slice (MultiBand) imaging, ultra-high spatial and temporal resolution imaging, new insights into neurovascular coupling, integrating functional MRI with diffusion MRI data, connectomics, Big Data analysis and machine learning, are offered in discussion sections.
       
      Human subject issues including informed consent, institutional review board requirements and safety in environments with high magnetic field strengths are presented.
       
      Two lectures per week, one laboratory session per week, and one discussion session per week. Laboratory sessions include fMRI data acquisition sessions at the 3 Tesla MRI scanner at MIT and the Connectom and 7 Tesla scanners at the Martinos Center @ MGH, Charlestown, as well as hands-on data analysis workshops.
       
      Assignments include readings of textbook chapters and primary literature as well as fMRI data analysis in the laboratory sessions. Knowledge of basic probability & statistics and linear algebra required; introductory or college-level neurobiology, physics, and signal processing would be helpful.
       
      Course Directors: Susan Whitfield-Gabrieli and Jonathan Polimeni
       
      Laboratory Director: Anastasia Yendiki
       
      Instructors: R. L. Gollub, L. Wald, B. Dickerson, S. Whitfield-Gabrieli, D. Bolar, J. Polimeni, D. Salat, M. Vangel, D. Greve, S. Pujol, D. McLaren, L. Nickerson, J. Augustinack, M. Sabuncu, K. Setsompop, J. Cohen-Adad, S. Ghosh, E. Konukoglu, A. Takahashi, T. Witzel, B. Rosen, A. Yendiki.
       
      For more information, contact Sue Whitfield-Gabrieli, Ph.D. or Jon Polimeni, Ph.D., visit the HST583 Course Website or download the course flyer.
       
       
       
      HEALTHCARE VENTURES – HST.978/15.367 (FORMERLY 15.S07)
       
      Next semester, we are running the fourth year of a class to teach the process of creating new ventures in healthcare.  The class will be an interdisciplinary mix of engineers, scientists, entrepreneurs, and clinicians. Check out the details below and please feel free to email me with any questions! Also – this is now an official HST class – this will be the first year we are offering this course with a designated HST catalog number!
       
      What: 15.367/HST.978 Healthcare Ventures: a scientific approach to starting healthcare and medical ventures 
       
      When & Where: Tuesdays, 5-8pm; E25-117
       
      Who: Anyone passionate about health and medicine (engineers, scientists, business students, and medical students) 
       
      How: If you are interested, apply here: http://bit.ly/1eySKq3
       
      Why do it: The goal of this class is to take ideas from Design Thinking and from the Lean Startup movement and combine them into a principled approach to starting companies in healthcare.  This approach leverages ideas of experimental design and hypothesis testing in order to accelerate the pace for evaluating and developing ideas and for positioning the idea to establish a new venture.  
       
      We have recruited a group of very experienced faculty who, together with their network, will provide extensive mentoring through this process.  In short, this course will provide a supportive, near real-world experience to help you make your mark in the Biomedical arena - or at the very least - provide you with a durable educational experience that will benefit you long beyond your time at MIT.
       
      This class is perfect for anyone with a new technology they want to turn into a company, or for anyone with a healthcare challenge in search of the perfect product, or just someone with the passion and energy to learn how to change healthcare.
       
      The class will be led by Professor Martha Gray the J.W. Kieckhefer Professor of Health Sciences and Technology and Zen Chu, Senior Lecturer at Sloan, and involves a variety of other faculty from the medical, engineering, and business communities.
       
      Please feel free to reach out to the TA Chris Lee (christopher.lee@mit.edu) with any questions. We look forward to seeing you! 
       
       
       
      TWO NEW BIOLOGY GRADUATE COURSES IN 2015-2016
       
      The  Biology department is offering two new graduate courses in 2015-2016.  
       
      The Hallmarks of Cancer (7.85) will be offered in fall 2015 and Protein Folding and Misfolding in Biology (7.87) will be offered in spring 2016.
       
      Course descriptions are available here.
       
       
       
      REGISTRATION - SUMMER 2015
       
      Online Registration for Summer 2015 opens on June 1, 2015. Graduate students who are enrolled in a research degree program and who are taking only thesis or pre-thesis research subjects during the summer will have their registration approved by their departments. All other students should contact their departments to discuss subject selection.
       
      Registration must be submitted by the end of the first week of the summer session (Friday, June 12). Registration submitted after this deadline is subject to a $50 late fee.
       
      Once the department has approved the registration selections, all subsequent changes to the student's program should be made via the Online Add Drop application.
       
      The last day of classes, Friday, August 14, is the deadline for adding and dropping subjects.
       
       
       
       

      Conferences, Lectures & Seminars

       

        COUNTWAY LIBRARY LECTURE - DR. NOA RAPPAPORT, WEITZMANN INSTITUTE OF SCIENCE

        • Thursday, August 13, 2015
        • 12:30-1:30pm
        • Countway Library, Room 423
        Dr. Noa Rappaport
        Department of Molecular Genetics
        The Weizmann Institute of Science, Rehovot, Israel
         
        MalaCards: a human disease compendium for in silico discovery
        Human diseases are at the heart of extensive research encompassing genomics, bioinformatics, systems biology, and systems medicine. Some of the challenges facing disease bioinformatics are disease nomenclature, integration of heterogeneous information from diverse sources, and generating a comprehensive and consistent view of gene-disease relationships. This is especially ambitious for complex diseases, where a concerted effort is needed to sort out signal from noise, necessitating the use of comprehensive disease and gene compendia with extensive cross-relationships.  Two relevant systems will be presented. The first is GeneCards (www.genecards.org), encompassing automatically mined information from ~120 data sources for ~150,000 gene entries. The second is MalaCards (www.malacards.org), a comprehensive resource of human diseases, with ~19,000 entries, mined from >60 sources. The development of MalaCards posed many algorithmic challenges, such as disease names unification, alias definition, integrated classification, and construction of a well-defined gene-disease matrix. The information in each of a MalaCard’s 17 sections is searchable, and the database provides a rich big-data scaffold for in-silco discovery of disease-related annotation, inter-relations and trends. Further, exploiting GeneCards and MalaCards information, we have constructed VarElect, a tool that affords effective sifting and prioritization of next generation sequencing genes and variants. VarElect’s capacity for indirect genes-phenotype-relations (guilt by association) is augmented by the integration of biological pathways from 12 sources in PathCards, affording optimal informativeness and minimal redundancy. Thus, MalaCards and its affiliated datasets provide comprehensive analytical capacities for biomedical research.
         
        Hosted by the Kohane Lab
         
         
        27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM
         
        Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
        • Thursday, October 1, 2015
        • 2–5:30pm
        • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
        Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
         
        Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
        New York University Langone Medical Center
         
        Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
         
        Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
         

        HARVARD UNIVERSITY'S INAUGURAL FORUM ON POPULATION HEALTH EQUITY 

        Harvard University's Inaugural Forum on Population Health Equity, will be hosted by the Harvard T.H. Chan School of Public Health, with generous support from the Aetna Foundation.

        • September 10-11, 2015 
        • Martin Conference Center, in the Harvard Longwood Area, of Boston, MA.
        We hope you will join us for the meeting, which will convene over 450 academics and professionals to network and hear domestic and global public health leaders address a range of population health equity issues, from racial inequities to macro-economic shocks.
         
        Registration for the meeting is free, but seats are limited. We encourage you to register today through the Forum website: http://tinyurl.com/PopHealthEquityForumOnline or Facebook page: http://www.Facebook.com/PopHealthEquity
         
        In the meantime, we hope you will encourage your colleagues, students and staff members to attend, as well as friend us Facebook and follow us on Twitter (@PopHealthEquity). 
         
        The latest agenda (also available online at http://tinyurl.com/UpdatedForumAgenda), flyer, and promotional banner are attached for your reference, and to share with others. You can access additional information about our diverse faculty of speakers here: http://tinyurl.com/ForumSpeakers, as well as watch special Forum welcome messages here: https://youtu.be/O9TAb4PtPfk and here: https://youtu.be/e4NDXRli6fQ

         

        LEADINGAGE HACKFEST

        LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

        A Youtube video about the event is available here.   
         
        Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

         

        PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

        • October 29-30th, 2015 
        • Seaport Hotel & World Trade Center, Boston
        This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
         
        The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
         
        Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
         
        For more information and to register, please visit the Symposium website:

         

        MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

        Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

        But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
         
        At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
         
        More information and events from Medtech Boston is available here.
         
         

        MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

        The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

        Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
         
        Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
         
        Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
         
         

        HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

        The HMS JPNM offers a weekly seminar series from September through May/June.
         
        Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
         
        S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
         
        If you would like to be added to the weekly email distribution list for the lectures, please contact:
        Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
         
        Upcoming Seminars:
         
        Stay tuned for Fall 2015 seminar information.

         
        BRAINMAP SEMINARS

        Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
         
        Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
         
        To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
         
        There are no more Brainmap regular seminars scheduled for the summer.
         
         
         
         

        Student Opportunities
         

        2ND ROUND CALL FOR APPLICATIONS - INSTITUTE COMMITTEES

        Serve on an Institute Committee for the 2015-16 Academic Year

        • Make an impact on community and student life issues
        • Shape MIT policy on graduate programs, corporation matters, and more
        • Develop relationships with peers, faculty and administrators from all across the Institute
        Submit your applications here - due Friday August 14th
         
        Contact Daniel Smithwick with any questions gsc-vp@mit.edu

         

        MIT VENTURESHIPS CLUB FALL 2015 START-UPS RECRUITMENT

        MIT Ventureships Club is providing a great opportunity for your start-ups to work with eager and motivated volunteer students on the business problems that you have in order to get information that you need.  We are seeking companies that are willing to meet regularly with student groups and act as mentors by sharing the experiences and lessons of successful entrepreneurs.

        Every semester, our club works with MIT Venture Mentoring Service to launch a Ventureships Program. In this program,we interview and select 4~5 early stage MIT start-ups as well as 10~20 MIT students. The students will work closely with the CEOs on market research, fund raising, technology development, etc, all of which are essential to the start-ups.
         
        As the Fall 2015 Ventureships Program is approaching, we are recruiting new early stage start-ups.
         
        Basic Requirements
        1. The company has at least 1 co-founders as MIT affiliated students, staff, or alumni.
        2. The company have a well-defined one semester project for the students. Your project proposals will be posted to the students and they will choose your company based on the descriptions as well as your pitch on our kick-off event. Click here to find past project proposals examples. Please submit your project proposal(s) before we arrange an interview with you.
        3. The CEO has enough time to interact with the MIT students.
        For more details and Application:
         
        If you are enthusiastic about entrepreneurship or have any questions, don't hesitate to contact us!

         

        KOCH INSTITUTE GRADUATE STUDENT FELLOWSHIPS

        The Koch Institute for Integrative Cancer Research is now soliciting proposals for several fellowships for graduate student support for Academic Year 2015/2016. Each source of funding has an emphasis on students working in the broad area of cancer research. Funds are available in the following categories:

        1.Seven (7) fellowships are available through Koch, Ludwig and other endowed funds for School of Science graduate students working in cancer research.

        2.One (1) fellowship is available through blended Koch Institute funds for an MIT graduate student working in cancer research.
         
        3.Three (3) fellowships are available through the Ludwig Research Funds in support of MIT graduate students with metastasis as their research focuses.
         
        Awards will fund academic year stipend (9-Months at the standard School of Science/Engineering stipend rate), medical insurance and tuition for each successful candidate.
         
        Selection criteria include demonstrated progress and accomplishments, cancer relevance and potential of student to realize the goals of the project. Preference will be given to students in the later years of their PhD research.
         
        The application should be written by the student and should make clear the relevance of the work to cancer research.  To be included:
        • Paper applications (three copies) should consist of:
          • Cover page with applicant name, MIT Academic Program and year of study, title of project, faculty supervisor and which of the categories of funding that you are applying for. Please also note if you have received previous fellowships from the KI.
          • Curriculum vitae.
          • 3 page (maximum) outline of student's research progress to date and plans for continuation of the thesis research.
          • One letter of recommendation is required. The letter should be from the student's faculty advisor and should summarize prior and current mechanisms for support. Letters may be mailed directly from the PI to Lori Spindler, 76-158,  (lorispin@mit.edu) or may be sealed in an envelope and included with the application.
        Applications must be received (Attn: Lori Spindler) by August 10, 2015 - no later than noon. No extensions will be granted and incomplete submittals will not be reviewed. 
         
        A faculty committee will review all applications and awards will be made effective September 1, 2015.
         
        NOTE: While there is no limit on the number of applications from an individual laboratory, it is not typical that more than one application from a laboratory would be funded.
         
         

        INTERN: MICROFLUIDIC DEVICE TO HOST MICRO-ORGANS

        The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 

        Project Scope: The position requires a development of a microfluidic device that will host micro-organs such as islets of Langerhans. The student will focus on design and fabrication of the microfluidic device. Multiple iterations will be fabricated and tested for cell compatibility and ease of operation. The student will be trained in design, micro-fabrication, microfluidics, and cell culture. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
         
        Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Experience in at least one CAD package is needed. Previous experience with cell culture, ELISA and microfluidics is desirable. Education: enrolled in an undergraduate program. 
         
        For more information, visit: http://www.karplab.net/.
         
         
        INTERN: MICRONEEDLE BASED ADHESIVE PATCH

        The Karp Lab at HST, Brigham & Women’s Hospital, Harvard Medical School aims to develop platform technologies supporting a broad range of potential applications in medicine and bioengineering. A major focus of our research group is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients. 
         
        Project Scope: The position requires a development of a microneedle based adhesive patch based on previous research in the lab (Published: http://dx.doi.org/10.1038/ncomms2715). Microneedles will be fabricated and tested for adhesion on animal tissue ex-vivo. Fabrication process and materials will be optimized to achieve maximal adhesion. Later these patches will be tested in vivo to investigate its efficacy in wound healing. The student will be trained in design, micro-fabrication, mechanical tester and tissue handling. In addition to this project, the student will also gain exposure to other translational projects in the lab as well - ranging from drug delivery, medical adhesives and engineered cells.
         
        Prerequisites: The intern is expected to be enthusiastic, sincere and most importantly a team player. The student is also expected to master his/her skills in research planning, scientific presentation, and writing. Background in polymer science is desirable.
         
        For more information, visit: http://www.karplab.net/.

         
        APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

        Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
        For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

         

        UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

        Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
        nomination.
         
        More information may be found here. 
         
         
        GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

        Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

        Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
        community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

        Open positions are as follows:

        • Addir Fellows — MIT Interfaith Dialogue (position open for 2015-16)
        • Data-Visualization: Blacks at MIT History Project (position open for 2015-16)
        • DSL Online Life Learning (position open for 2015-16)
        • Financial Lieracy Fellow (position open for 2015-16)
        • Graduate Accomplishments: Writer (position open for 2015-16)
        • Graduate Orientation (position open for 2015-16)
        • GSC Creative Media Manager (position open for 2015-16)
        • Institute Community and Equity Office (one position open for 2015-16)
        • Language Conversation Excahnge (position open for 2015-16)
        • Programs for women (one position open for 2015-16)
        • Violence Prevention & Response: Programming Development (position open for 2015-16)
        Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
        We are accepting applications now and will fill positions on a rolling basis.
        Receive a monthly stipend while you gain experience.  Apply now!
        Questions? Contact Heather Konar (konar@mit.edu)

         

        COMMUNITY SERVICE WEEKLY BULLETIN

        At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
        Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
         
        As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
        efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
         
        Sign up for the weekly Community Service Bulletin of Events and Programs here.
        News and upcoming events are posted on the homepage.

         

         


        Professional Opportunities

         

        STANFORD UNIVERSITY: BIODESIGN INNOVATION FELLOWSHIP

        The Biodesign Fellowship is an intensive, year-long experience in identifying and characterizing clinical needs, inventing and prototyping solutions and developing business strategies for implementing these technologies. Join a team of the country's top young medtech innovators and experience what it's like to bring a new technology forward toward patient care.

        Changing Healthcare through Innovation.
        http://biodesign.stanford.edu/fellowship
        Deadline: August 31, 2015
         
         

        CONSULTANT POSITION AT CLEARVIEW HEALTHCARE PARTNERS

        ClearView Healthcare Partners is a premier life sciences consulting firm serving clients within the biopharmaceutical, medical device, and diagnostics spaces.  We provide world-class strategic decision-making support across a wide diversity of business issues.  Our goal is to inform actionable recommendations that allow companies to achieve their business objectives.

        ClearView represents a unique opportunity for professional growth and client impact.  We were recently ranked #15 in Vault.com’s Consulting Fifty based on our commitment to training, professional development, and providing meaningful value for our clients.
         
        At ClearView, you will encounter an entrepreneurial environment, interact with a dynamic group of colleagues, present to clients in critical business situations, and develop a deep understanding of the life sciences and biopharmaceutical industry.  You will be mentored directly by ClearView partners and managers, who have a wealth of experience in life sciences consulting.  In addition, you will be exposed to a wide variety of business issues ranging from new product planning and business development to product commercialization.
         
        You will interact with both clients and teams within ClearView to address critical strategic questions within the biopharmaceutical space.  During the course of a typical project, you will engage in a number of activities, including:
        • Conduct complex problem-solving through a hypothesis-based approach
        • Complete primary and secondary research to drive to critical insights
        • Create and utilize analytic tools (e.g., forecast models) to support key decision-making
        • Communicate recommendations to clients to inform strategy and maximize value
         
        At ClearView, you will have the opportunity to lead projects and develop a broad range of expertise, skills, and connections that will serve as a foundation and springboard for your career.
         
        Qualifications:
        We are seeking consultant-level candidates with post-graduate degrees in the life sciences (i.e., Ph.D. or M.D.) or that plan to graduate by summer 2016.  Although prior business or consulting experience is not necessary, all candidates should have a demonstrated interest in the biopharmaceutical industry.  Candidates must be highly analytical in their approach to solving complex problems, should be proficient in both written and oral communication, and must enjoy working within a dynamic team environment.
         
        If you are interested in an enriching professional experience within the life sciences, we would welcome your application.
         
        Notes:
        Please apply through our website by uploading your resume and cover letter:
         
        Candidates must be willing to relocate to Boston, MA area.
         
        Application Submission Deadline: 11:59 PM EST on Sunday, August 16, 2015
        Interviews Begin: Tuesday, August 25, 2015
         
        Contact: Nicole Davis (nicole.davis@clearviewhcp.com)

         

        POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

        A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

        Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

         

        RESEARCH AND DEVELOPMENT SCIENTIST POSITION

        Aptitude Medical Systems Inc. – Santa Barbara, CA

        Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
         
        Summary
        There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
         
        Why Choose Aptitude
        We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
        We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
         
        Responsibilities
        The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
        • Develop, test, and optimize aptamers, assays and other products
        • Design and execute experiments; process, analyze, and interpret experimental results and data
        • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
        • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
        • Develop original solutions to problems and create new experimental strategies
        • Help set project goals, milestones and continuously track progress and success
        • Prioritize and manage technical tasks for concurrent projects
        • Help and support other project teams or groups when needed
         
        Knowledge, Skills, and Abilities Required
        The four fundamental characteristics that we need on the team are:
        • Willingness to take on any responsibility to enable the team to achieve success
        • A sense of urgency and ability to achieve time-sensitive milestones
        • Persistence to work through challenges and unlock both systematic and creative solutions 
        • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
         
        In addition, we look for the following skills and abilities in top candidates:
        • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
        • Meticulous attention to detail, executing with high accuracy and reproducibility
        • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
        • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
        • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
        • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
         
        Education/Experience Required
        Different combinations of experience and educations will be considered for qualification of this position:
        • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
        • At least four years of work-related experience in a relevant laboratory environment
        • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

         
        PORTAL INSTRUMENTS POSITION AVAILABLE

        Lead Firmware Engineer
         
        About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
         
        Working at Portal Instruments:
        • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
        • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
        • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
        Role and Responsibilities:
        • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
        • Design, build, debug, and optimize the device’s firmware
        • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
        • Integrate with a team of firmware, software, and control engineers.
        • Design, build, debug, and optimize firmware
        • Evaluate system performance by designing, executing, and documenting experimental plans.
        • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
        • Support electrical compliance testing.
        • Support the manufacture and testing of electronic assemblies by providing test procedures
        • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
        Required Skills and Experience:
        • Development of efficient microcontroller firmware in C, preferably ARM.
        • Familiarity with quality system requirements for medical software system development.
        • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
        • Experience with high-bandwidth motion control.
        • Sensor synthesis / sensor fusion.
        • Familiarity with electronic hardware design.
        • Automated integration testing of firmware.
        Qualifications:
        • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
        • 5+ years of experience in commercial development and/or validation.
        • Experience with medical products development and FDA or related product approvals a plus.
        • Outstanding software engineering and design skills.
        • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
        • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
        • Ability to work independently in a start-up environment.
        Salary commensurate with experience; potential equity participation.
         
        To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
         

         

        10X GENOMICS - POSITIONS AVAILABLE

        10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

        Applications Scientist: Computational Biology
        10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
         
        Computational Biologist: Algorithm Development
        10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
         
        Computer Scientist: Algorithm Development
        Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
         
        We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

        Data Scientist
        10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
         
        For more information about the company and to see the job listings, visit: 10xgenomics.com/company

        To apply for a position please contact jobs@10xgenomics.com

         

        POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

        GRADUATE STUDENT and/or POSTDOCTORAL ASSOCIATE: contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG), has the potential to provide the first direct evidence for life on Mars and/or on icy moons as well as to enable diverse environmental and clinical applications. Will have an opportunity to develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches; and to design, develop, and validate the instrument in the lab and in the field at terrestrial analogs of Mars or other extreme environments.
        This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. Will work closely with the science PI, Christopher Carr (carrlab.org); the project PI, Maria Zuber, at MIT; the MGH institutional PI, Gary Ruvkun; and other academic and industrial partners.
         
        REQUIREMENTS: a Ph.D. in a relevant field; strong analytical and problem solving skills; and excellent interpersonal, communication, and technical skills.  Seek highly motivated individual with who is able to work independently and contribute to an interdisciplinary team. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills are highly valued.
         
        APPLY: See directions online at http://setg.mit.edu/positions or contact chrisc@mit.edu.

         

        RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

        Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu .

        Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

         

        FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

        Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

        The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

        Responsibilities:

        1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
        2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
        3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
        Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
         
        Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
         
        Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
         
        Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
         
        Availability: Spring 2015 graduates and other recent graduates.
         
        Citizenship: Must be a United States citizen to be eligible for the position.  
         
        Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
         
        Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
         
         

        ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

        Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

        We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

        To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

         

        POSTDOCTORAL FELLOW POSITION - JAIN LAB

        Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
         
        Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
         
        Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
         
         

        IMMUNEERING - POSITIONS AVAILABLE

        Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
         
        This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
         
        Pathway Biology
        Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
         
        Neurodegeneration and CNS Diseases
        Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
         
        Oncology
        Expertise in disease biology and data analysis for cancer research.
         
        Computational Biology
        Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
         
        Next Generation Sequencing (NGS)
        Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
         
        Machine Learning/Statistics (with Biological Applications)
        Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
         
        Responsibilities
        • Develop innovative algorithms and methods for analyzing data to identify biological insights
        • Interpret data from a biological and clinical perspective
        • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
        • Collaborate with colleagues to solve complex computational research problems
        • Present scientific material (written and oral) to diverse audiences
        Minimum Qualifications
        • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
        • Demonstrated experience developing novel algorithms to address complex scientific problems
        • Proven ability to work independently as well as contribute to larger initiatives
        • Effective English communication skills (both written and oral)
        • Proficient in at least one of R, Python, MATLAB, or a similar language.
        • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
        • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
        Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
        • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
        • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
        • Proficient in R
        • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
        For more information, please visit www.immuneering.com
         
        If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

         

        IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

        For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

        Visit IIE online at www.iie.org.
        Please contact the programs directly for additional information or with any questions you may have.
         
        A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

         
         

        Career Programs

         

        PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

        The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
        Dates for the remainder of the 201 Series are listed below:
        • September 22, 2015: Career Paths in Big DataRegister here.
        • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
        • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
         
        MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
         
        Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
         
        Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
         
        Web Presentations 
        We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
         
        MD Fellowship 
        We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
        Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
         
        Diversity & Inclusion at McKinsey 
        At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
         
                  

        GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

        For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

        The GECD Event calendar can be found here. 
         
         

        GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

        Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
         
         

        MIT CAREERBRIDGE

        There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

         

        Follow HST on Twitter Follow mit_hst on Twitter

         

         

        This week in HST - August 21, 2015 - Volume 16, Number 43

        $
        0
        0

        HST Community Notices
         

         

        Course Information &
        Academic Resources

        Conferences, Lectures & Seminars
         

        Student Opportunities
         

        Professional Opportunities
         

        Career Programs
         


        HST Community Notices

         

        HST FACULTY POSTER SESSION

        Students and faculty are warmly invited to participate in HST's annual Faculty Poster Session--designed to inform MD and PhD students about research opportunities and to allow faculty to recruit new students to their labs.  
         
        This year’s session will take place:
        • Thursday, September 24, 2015
        • 5-7pm 
        • Harvard Medical School, TMEC Atrium
          Refreshments will be served.
        Posters may take any form in a 4' by 4' format, ranging from an overview of an entire research portfolio to sample results of a recent research project.  
         
        Faculty and students may register a poster at https://hst.mit.edu/go/poster-session.

        If you have any questions, please write to hst-postersession@mit.edu.

         

        KENNETH RAININ FOUNDATION INNOVATIONS SYMPOSIUM POSTER AWARDS

        MEMP PhD candidate, Ben Mead and his team from Jeff Karp's lab took home two poster prizes (of four awarded)  at the prestigious Kenneth Rainin Foundation Innovations Symposium: Wound Healing, Repair and IBD, held in San Francisco on July 20-21, 2015. More information on the symposium and the posters can be found here.

        Congratulations to Ben and team and Jeff!
         

        HST BBQ ON THE QUADRANGLE AT HMS

        • Wednesday, August 26, 2015
        • 4:30-7:30pm
        • HMS Quadrangle, Longwood Ave., Boston
        Music!  Food!  Beverages!  Good Company!
         
        RSVP to Patty Cunningham (pcunningham@hms.harvard.edu
        Enjoy the summer!

         

        IMES DISTINGUISHED SPEAKER SERIES

        The IMES Distinguished Speaker Series invites you to attend a lecture by Dr. Helen Mayberg.
         
        "Targeted Therapeutic Modulation of Depression Circuits using Deep Brain Stimulation" 
        • Thursday, September 17, 2015
        • 4:30pm
        • E25-111
        Helen Mayberg, M.D. is Professor of Psychiatry, Neurology and Radiology and the Dorothy Fuqua Chair in Psychiatric Neuroimaging and Therapeutics at Emory University.  Over the last 25 years, her multi-disciplinary depression research team has worked to integrate cutting-edge imaging strategies, quantitative behavioral and psychophysiological metrics, and experimental treatment trials to define brain-based biomarkers that can optimize treatment selection for individual patients.  This work was foundational for the first studies of subcallosal cingulate deep brain stimulation for treatment resistant depression and remains the cornerstone of current studies to both refine and optimize DBS implementation and characterize network mechanisms mediating its antidepressant effects. Dr. Mayberg is a neurologist, trained at Columbia's Neurological Institute in New York, with fellowship training in nuclear medicine at Johns Hopkins. She is a member of the Institute of Medicine, among other honors, and participates in a wide variety of advisory and scientific activities across multiple fields in neuroscience.  
         
        Abstract:
        Deep Brain Stimulation is an emerging treatment strategy for patients with intractable depression with imaging playing a crucial role in the development, testing and refinement of the procedure. Multimodal modeling of structural and functional connections combined with real-time behavioral, autonomic and electrophysiological metrics are now used to more precisely identify the optimal target location as well as track long-term stimulation effects. Together these studies offer a unique perspective on critical pathways and mechanisms mediating antidepressant effects of DBS, and on the pathophysiology of treatment resistant depression more generally. 
         

         

        HST MEMP ALUMNI PROFILES

        Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
         

        HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

        "Step outside your comfort zone. The perspective will surprise you."
         
        The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
         
        Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
         
         

        Course Information & Academic Resources

         
        HARVARD CATALYST’S MEDICAL DEVICE DEVELOPMENT COURSE
         
        We are now accepting applications for Harvard Catalyst’s Medical Device Development course. This two-day course will provide an introduction to medical device innovation, development, and translation. We appreciate all of your efforts to promote this course to your academic and professional community.
         
        Medical Device Development
        • October 29-30, 2015
        • Sheraton Commander Hotel, Cambridge, MA
        • Apply by September 18, 2015!
        This course is tuition-free for Harvard-affiliated institutions.  
         
        For more information and a detailed description of Medical Device Development, please visit http://catalyst.harvard.edu/services/mdd/
         
        Contact us at med_devices@catalyst.harvard.edu with any questions.
         
        Joanna Chang, Education Program Developer, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
        Phone: 617-432-7113, Fax: 617-432-1560
         
        Casey Falla, Education Program Coordinator, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
        Phone: 617-432-7812, Fax: 617-432-1560
         
         
         
        CALLING FOR LIFE SCIENCES ENTREPRENEURS
         
        Do you have an idea you’d like to commercialize? Would you like to use Boston’s top scientific minds to help you build a business plan, get feedback from leading entrepreneurs & venture capitalists, and take the next step towards commercializing your biomedical brainchild?
         
        You are invited to submit a biomedical idea/invention for use in the 2015 Healthcare Innovation and Commercialization course. Submission will be reviewed based on commercialization potential, originality, and clinical relevance.
         
        PI’s, postdocs, and students are all encouraged to submit their inventions, which will be protected by NDA agreements from course participants.
         
        Please email your idea as a 1-page pdf document to harvardhic2015@gmail.com.

        Submitted ideas should include the following: 
        1) A brief description of yourself and your motivation to submit your idea
        2) Brief background on the problem you're trying to solve
        3) Description of your proposed solution
         
        Please visit http://www.harvardhic2015.com/curriculum.html for more information. 
        We look forward to hearing about your innovative ideas!
         
        HIC Team 2015
         
         
        10.807/15.371 INNOVATION TEAMS (“I-TEAMS”)
        • Wednesdays 4:30-7pm & Fridays 9-10:30am
        • 32-124
        • 12 units
        Instructors: Dr. Luis Perez-Breva (School of Engineering), Dr. Noubar Afeyan (Flagship Ventures & MIT Sloan), Prof. Fiona Murray (MIT Sloan & Trust Center for Entrepreneurship)
         
        “Innovation Teams is the class that transforms MIT technologies to ones that can impact the world.”
         
        Course Description:

        i-Teams is a graduate course offered jointly between the Schools of Engineering and Management. Students choose from a set of recent breakthrough technologies selected by the Class Faculty from MIT labs on the basis of their excitement and commercial potential.  Working in cross-disciplinary teams of 3-5 class peers plus an industry “catalyst”, students focus throughout the semester on exploring a commercialization strategy for their technology and developing a final recommendation for the next steps and the best vehicle to bring the project to impact (e.g. startup, license, NGO).

         
        Course Objectives:
        • Synthesize opportunities for innovation by iterating between technology and the market
        • Identify and leverage resources in an innovation ecosystem
        • Create an actionable go-to-market plan
        • Work with peers from different disciplines
        Course Composition:
         
        Approximately 50% of students are from the Sloan School and 50% are Graduate Students from the Schools of Engineering, Science, Architecture and HASS.   No experience is necessary.  Successful students come with an interest in innovation and a readiness to engage in the innovation process.  Advanced undergrads may take the class with instructor approval.
         
        Enrollment is limited.  Priority will be given to students who apply early.  Please visit the i-Teams website at http://iteams.mit.edu for application and registration details or email iTeams-TA@mit.edu with any questions.
         
         
        HST.583 - FUNCTIONAL MAGNETIC RESONANCE IMAGING: DATA ACQUISITION AND ANALYSIS
         
        This course provides the full background necessary for understanding functional MRI and the instruction on designing and conducting fMRI studies in the human brain, including data acquisition, analysis, and interpretation.
         
        In-depth coverage of the physics of MR signal generation and image encoding, the mechanisms of anatomical and functional contrasts, the physiological basis of the fMRI signals, cerebral hemodynamics, and neurovascular coupling are provided. Basic neuroanatomy, vascular anatomy, and physiology are reviewed.
         
        Design methods for stimulus-, task-driven and resting-state fMRI experiments will be taught; workflows for model-based and data-driven analysis methods for fMRI data are taught. Brain structure analysis and automatic segmentation and registration methods for surface- and region-based analyses of fMRI data are taught.
         
        Guided exploration of special advanced topics including accelerated parallel imaging and Simultaneous Multi-Slice (MultiBand) imaging, ultra-high spatial and temporal resolution imaging, new insights into neurovascular coupling, integrating functional MRI with diffusion MRI data, connectomics, Big Data analysis and machine learning, are offered in discussion sections.
         
        Human subject issues including informed consent, institutional review board requirements and safety in environments with high magnetic field strengths are presented.
         
        Two lectures per week, one laboratory session per week, and one discussion session per week. Laboratory sessions include fMRI data acquisition sessions at the 3 Tesla MRI scanner at MIT and the Connectom and 7 Tesla scanners at the Martinos Center @ MGH, Charlestown, as well as hands-on data analysis workshops.
         
        Assignments include readings of textbook chapters and primary literature as well as fMRI data analysis in the laboratory sessions. Knowledge of basic probability & statistics and linear algebra required; introductory or college-level neurobiology, physics, and signal processing would be helpful.
         
        Course Directors: Susan Whitfield-Gabrieli and Jonathan Polimeni
         
        Laboratory Director: Anastasia Yendiki
         
        Instructors: R. L. Gollub, L. Wald, B. Dickerson, S. Whitfield-Gabrieli, D. Bolar, J. Polimeni, D. Salat, M. Vangel, D. Greve, S. Pujol, D. McLaren, L. Nickerson, J. Augustinack, M. Sabuncu, K. Setsompop, J. Cohen-Adad, S. Ghosh, E. Konukoglu, A. Takahashi, T. Witzel, B. Rosen, A. Yendiki.
         
        For more information, contact Sue Whitfield-Gabrieli, Ph.D. or Jon Polimeni, Ph.D., visit the HST583 Course Website or download the course flyer.
         
         
         
        HEALTHCARE VENTURES – HST.978/15.367 (FORMERLY 15.S07)
         
        Next semester, we are running the fourth year of a class to teach the process of creating new ventures in healthcare.  The class will be an interdisciplinary mix of engineers, scientists, entrepreneurs, and clinicians. Check out the details below and please feel free to email me with any questions! Also – this is now an official HST class – this will be the first year we are offering this course with a designated HST catalog number!
         
        What: 15.367/HST.978 Healthcare Ventures: a scientific approach to starting healthcare and medical ventures 
         
        When & Where: Tuesdays, 5-8pm; E25-117
         
        Who: Anyone passionate about health and medicine (engineers, scientists, business students, and medical students) 
         
        How: If you are interested, apply here: http://bit.ly/1eySKq3
         
        Why do it: The goal of this class is to take ideas from Design Thinking and from the Lean Startup movement and combine them into a principled approach to starting companies in healthcare.  This approach leverages ideas of experimental design and hypothesis testing in order to accelerate the pace for evaluating and developing ideas and for positioning the idea to establish a new venture.  
         
        We have recruited a group of very experienced faculty who, together with their network, will provide extensive mentoring through this process.  In short, this course will provide a supportive, near real-world experience to help you make your mark in the Biomedical arena - or at the very least - provide you with a durable educational experience that will benefit you long beyond your time at MIT.
         
        This class is perfect for anyone with a new technology they want to turn into a company, or for anyone with a healthcare challenge in search of the perfect product, or just someone with the passion and energy to learn how to change healthcare.
         
        The class will be led by Professor Martha Gray the J.W. Kieckhefer Professor of Health Sciences and Technology and Zen Chu, Senior Lecturer at Sloan, and involves a variety of other faculty from the medical, engineering, and business communities.
         
        Please feel free to reach out to the TA Chris Lee (christopher.lee@mit.edu) with any questions. We look forward to seeing you! 
         
         
         
        TWO NEW BIOLOGY GRADUATE COURSES IN 2015-2016
         
        The  Biology department is offering two new graduate courses in 2015-2016.  
         
        The Hallmarks of Cancer (7.85) will be offered in fall 2015 and Protein Folding and Misfolding in Biology (7.87) will be offered in spring 2016.
         
        Course descriptions are available here.
         
         
         

         


        Conferences, Lectures & Seminars

         

          WINFOCUS CONFERENCE

          11th WINFOCUS World Congress on Ultrasound in Emergency and Critical Care Conference

          • October 22-2015
          • The Joseph B. Martin Conference Center at Harvard Medical School (77 Avenue Louis Pasteur, Boston, MA)
          World Interactive Network Focused On Critical Ultrasound (WINFOCUS) is a multi-specialty, international organization that is now a decade old and helps to promote point of care utilization and education throughout the world.
           
          It will be a great group of super-users, highly interactive and informational and lots of networking opportunities!

          There will be special sessions on medical student curriculum development and a competency assessment discussion panel which might be of interest too.
           
          More information is available at: http://www.winfocus2015.com/.
           
           

          27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM

          Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
          • Thursday, October 1, 2015
          • 2–5:30pm
          • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
          Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
           
          Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
          New York University Langone Medical Center
           
          Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
           
          Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
           

           

          HARVARD UNIVERSITY'S INAUGURAL FORUM ON POPULATION HEALTH EQUITY 

          Harvard University's Inaugural Forum on Population Health Equity, will be hosted by the Harvard T.H. Chan School of Public Health, with generous support from the Aetna Foundation.

          • September 10-11, 2015 
          • Martin Conference Center, in the Harvard Longwood Area, of Boston, MA.
          We hope you will join us for the meeting, which will convene over 450 academics and professionals to network and hear domestic and global public health leaders address a range of population health equity issues, from racial inequities to macro-economic shocks.
           
          Registration for the meeting is free, but seats are limited. We encourage you to register today through the Forum website: http://tinyurl.com/PopHealthEquityForumOnline or Facebook page: http://www.Facebook.com/PopHealthEquity
           
          In the meantime, we hope you will encourage your colleagues, students and staff members to attend, as well as friend us Facebook and follow us on Twitter (@PopHealthEquity). 
           
          The latest agenda (also available online at http://tinyurl.com/UpdatedForumAgenda), flyer, and promotional banner are attached for your reference, and to share with others. You can access additional information about our diverse faculty of speakers here: http://tinyurl.com/ForumSpeakers, as well as watch special Forum welcome messages here: https://youtu.be/O9TAb4PtPfk and here: https://youtu.be/e4NDXRli6fQ

           

          LEADINGAGE HACKFEST

          • October 30-November 1, 2015 
          • UMass, Boston

          LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

          A Youtube video about the event is available here.   

          Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

           

          PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

          • October 29-30, 2015 
          • Seaport Hotel & World Trade Center, Boston
          This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
           
          The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
           
          Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
           
          For more information and to register, please visit the Symposium website:

           

          MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

          Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

          But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
           
          At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
           
          More information and events from Medtech Boston is available here.
           
           

          MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

          The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

          Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
           
          Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
           
          Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
           
           

          HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

          The HMS JPNM offers a weekly seminar series from September through May/June.
           
          Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
           
          S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
           
          If you would like to be added to the weekly email distribution list for the lectures, please contact:
          Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
           
          Upcoming Seminars:
           
          Stay tuned for Fall 2015 seminar information.

           
          BRAINMAP SEMINARS

          Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
           
          Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
           
          To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
           
          There are no more Brainmap regular seminars scheduled for the summer.
           
           
           
           

          Student Opportunities
           

          MIT VETERANS OUTREACH

          Veteran Students, do you know . . .
           
             there are two MIT veteran student clubs.
             that there is a committee dedicated to veterans outreach comprised of faculty, staff and students.
             that room 50-010 is a space exclusively for veteran students.
           
          Interested in knowing more, please contact Mary Kathryn, extension 4.7824 or mjuskiew@mit.edu.

           

          MIT VENTURESHIPS CLUB FALL 2015 START-UPS RECRUITMENT

          MIT Ventureships Club is providing a great opportunity for your start-ups to work with eager and motivated volunteer students on the business problems that you have in order to get information that you need.  We are seeking companies that are willing to meet regularly with student groups and act as mentors by sharing the experiences and lessons of successful entrepreneurs.

          Every semester, our club works with MIT Venture Mentoring Service to launch a Ventureships Program. In this program,we interview and select 4~5 early stage MIT start-ups as well as 10~20 MIT students. The students will work closely with the CEOs on market research, fund raising, technology development, etc, all of which are essential to the start-ups.
           
          As the Fall 2015 Ventureships Program is approaching, we are recruiting new early stage start-ups.
           
          Basic Requirements
          1. The company has at least 1 co-founders as MIT affiliated students, staff, or alumni.
          2. The company have a well-defined one semester project for the students. Your project proposals will be posted to the students and they will choose your company based on the descriptions as well as your pitch on our kick-off event. Click here to find past project proposals examples. Please submit your project proposal(s) before we arrange an interview with you.
          3. The CEO has enough time to interact with the MIT students.
          For more details and Application:
           
          If you are enthusiastic about entrepreneurship or have any questions, don't hesitate to contact us!

           

          APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

          Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
          For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

           

          UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

          Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
          nomination.
           
          More information may be found here. 
           
           
          GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

          Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

          Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
          community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

          Open positions are as follows:

          • Addir Fellows — MIT Interfaith Dialogue (position open for 2015-16)
          • Data-Visualization: Blacks at MIT History Project (position open for 2015-16)
          • DSL Online Life Learning (position open for 2015-16)
          • Financial Lieracy Fellow (position open for 2015-16)
          • Graduate Accomplishments: Writer (position open for 2015-16)
          • Graduate Orientation (position open for 2015-16)
          • GSC Creative Media Manager (position open for 2015-16)
          • Institute Community and Equity Office (one position open for 2015-16)
          • Language Conversation Excahnge (position open for 2015-16)
          • Programs for women (one position open for 2015-16)
          • Violence Prevention & Response: Programming Development (position open for 2015-16)
          Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
          We are accepting applications now and will fill positions on a rolling basis.
          Receive a monthly stipend while you gain experience.  Apply now!
          Questions? Contact Heather Konar (konar@mit.edu)

           

          COMMUNITY SERVICE WEEKLY BULLETIN

          At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
          Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
           
          As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
          efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
           
          Sign up for the weekly Community Service Bulletin of Events and Programs here.
          News and upcoming events are posted on the homepage.

           

           


          Professional Opportunities

           

          VL34 - SCIENTIST/SENIOR SCIENTIST IN MOLECULAR BIOLOGY

          VL34, Inc. has an immediate opening for a Scientist/Senior Scientist in molecular biology.  VL34 is an early-stage startup in Cambridge, MA using cutting-edge molecular techniques to help create a novel category of fertility treatment. VL34 was founded by VentureLabs, a unit of Flagship Ventures which has launched over 25 breakthrough companies including Seres Therapeutics, Symbiota, Pronutria, and Moderna Therapeutics. 

          Position Summary
          VL34, Inc. is seeking an exceptional, highly motivated Scientist/Senior Scientist to play a key role in the company’s efforts to build a high-throughput platform to identify molecular targets with applications in the fertility field.  As part of the early team of scientists at VL34, this individual will have wide-ranging responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative group.
           
          Key Qualifications
          Ph.D. in Biology or a related field, with or without postdoc or industry experience 
          Ability to think critically and creatively as part of a fast-paced research team
          Proven hands-on experience with standard molecular biology techniques.
          Especially preferred to have experience with one or more of:
          oCustom library preparation for high-throughput sequencing, single cell or low-input detection
          oProtein engineering, library-based display technologies (yeast, phage), in vitro directed evolution and selection
          Enthusiasm for pushing the frontiers of conventional techniques and comfort in venturing beyond one’s area of expertise
          Great hands in the laboratory and resourceful when starting new techniques from scratch
          Excellent collaboration, communication and interpersonal skills

          Responsibilities
          The successful candidate will work closely with an interdisciplinary team as well as independently to design and execute experiments that support research activities and project goals
          Quickly implement state-of-the-art techniques in new biological models
          Identify modifications to iteratively improve protocols
          Analyze data and help identify molecular targets and follow-up experiments
          Participate in various aspects of the company from establishing collaborations to writing patents to long-term planning
           
          Compensation
          A competitive overall compensation package including: competitive base salary, bonus potential and stock options.
           
          Contact Information
          To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Brian at VL34Jobs@gmail.com.

           

          PURETECH - SENIOR ANALYST

          About PureTech

          PureTech is a science-driven healthcare company, seeking to solve some of today’s toughest health challenges through disruptive approaches. Based in Boston, PureTech has a network of more than 50 experts across multiple disciplines – from entrepreneurs to world-renowned scientists – giving PureTech access to potentially groundbreaking science and technological innovations. PureTech is problem-focused and solution-agnostic, looking beyond traditional disciplines and approaching healthcare problems from different perspectives. Focusing on areas of significant unmet medical need, PureTech evaluates more than 650 ideas per year, prioritizing, testing and selecting what it believes to be the most scientifically and commercially promising concepts to advance.
           
          JOB DESCRIPTION:
          The Senior Analyst will get hands-on experience in entrepreneurship, participate in sourcing and due diligence of technologies and support PureTech's Innovations and team members. This includes:
          Ideation and business planning for next generation technologies
          Conducting strategic analyses & market opportunity assessments
          Undertaking project management & operations of innovations including development of cutting edge technologies
          Participating in analysis and development of intellectual property
          Preparing compelling communication materials, including presentations, for key external stakeholders
           
          QUALIFICATIONS:
          Creativity, smarts & initiative
          PhD in one of the following disciplines from a top tier institution: engineering, physics, computer science, or a life sciences related field
          Business experience is a plus but not required
          Strong presentation and communication skills; candidate should feel comfortable presenting to groups
           
          LOCATION: Boston, Massachusetts
          The position is full time with a competitive salary and benefits. This is a unique opportunity to join one of the most innovative companies in healthcare while getting hands-on startup experience in our Innovations. Please send your resume and cover letter to careers@puretechhealth.com. Be sure to indicate the Senior Analyst Position in the subject of your email.  (E-mail applications sent directly to PureTech staff will not be considered)
           

           

          STANFORD UNIVERSITY: BIODESIGN INNOVATION FELLOWSHIP

          The Biodesign Fellowship is an intensive, year-long experience in identifying and characterizing clinical needs, inventing and prototyping solutions and developing business strategies for implementing these technologies. Join a team of the country's top young medtech innovators and experience what it's like to bring a new technology forward toward patient care.

          Changing Healthcare through Innovation.
          http://biodesign.stanford.edu/fellowship
          Deadline: August 31, 2015
           
           

          POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

          A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

          Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

           

          RESEARCH AND DEVELOPMENT SCIENTIST POSITION

          Aptitude Medical Systems Inc. – Santa Barbara, CA

          Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
           
          Summary
          There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
           
          Why Choose Aptitude
          We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
          We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
           
          Responsibilities
          The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
          • Develop, test, and optimize aptamers, assays and other products
          • Design and execute experiments; process, analyze, and interpret experimental results and data
          • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
          • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
          • Develop original solutions to problems and create new experimental strategies
          • Help set project goals, milestones and continuously track progress and success
          • Prioritize and manage technical tasks for concurrent projects
          • Help and support other project teams or groups when needed
           
          Knowledge, Skills, and Abilities Required
          The four fundamental characteristics that we need on the team are:
          • Willingness to take on any responsibility to enable the team to achieve success
          • A sense of urgency and ability to achieve time-sensitive milestones
          • Persistence to work through challenges and unlock both systematic and creative solutions 
          • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
           
          In addition, we look for the following skills and abilities in top candidates:
          • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
          • Meticulous attention to detail, executing with high accuracy and reproducibility
          • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
          • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
          • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
          • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
           
          Education/Experience Required
          Different combinations of experience and educations will be considered for qualification of this position:
          • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
          • At least four years of work-related experience in a relevant laboratory environment
          • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

           
          PORTAL INSTRUMENTS POSITION AVAILABLE

          Lead Firmware Engineer
           
          About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
           
          Working at Portal Instruments:
          • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
          • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
          • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
          Role and Responsibilities:
          • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
          • Design, build, debug, and optimize the device’s firmware
          • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
          • Integrate with a team of firmware, software, and control engineers.
          • Design, build, debug, and optimize firmware
          • Evaluate system performance by designing, executing, and documenting experimental plans.
          • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
          • Support electrical compliance testing.
          • Support the manufacture and testing of electronic assemblies by providing test procedures
          • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
          Required Skills and Experience:
          • Development of efficient microcontroller firmware in C, preferably ARM.
          • Familiarity with quality system requirements for medical software system development.
          • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
          • Experience with high-bandwidth motion control.
          • Sensor synthesis / sensor fusion.
          • Familiarity with electronic hardware design.
          • Automated integration testing of firmware.
          Qualifications:
          • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
          • 5+ years of experience in commercial development and/or validation.
          • Experience with medical products development and FDA or related product approvals a plus.
          • Outstanding software engineering and design skills.
          • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
          • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
          • Ability to work independently in a start-up environment.
          Salary commensurate with experience; potential equity participation.
           
          To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
           

          10X GENOMICS - POSITIONS AVAILABLE

          10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

          Applications Scientist: Computational Biology
          10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
           
          Computational Biologist: Algorithm Development
          10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
           
          Computer Scientist: Algorithm Development
          Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
           
          We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

          Data Scientist
          10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
           
          For more information about the company and to see the job listings, visit: 10xgenomics.com/company

          To apply for a position please contact jobs@10xgenomics.com

           

          POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

          GRADUATE STUDENT and/or POSTDOCTORAL ASSOCIATE: contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG), has the potential to provide the first direct evidence for life on Mars and/or on icy moons as well as to enable diverse environmental and clinical applications. Will have an opportunity to develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches; and to design, develop, and validate the instrument in the lab and in the field at terrestrial analogs of Mars or other extreme environments.
          This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. Will work closely with the science PI, Christopher Carr (carrlab.org); the project PI, Maria Zuber, at MIT; the MGH institutional PI, Gary Ruvkun; and other academic and industrial partners.
           
          REQUIREMENTS: a Ph.D. in a relevant field; strong analytical and problem solving skills; and excellent interpersonal, communication, and technical skills.  Seek highly motivated individual with who is able to work independently and contribute to an interdisciplinary team. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills are highly valued.
           
          APPLY: See directions online at http://setg.mit.edu/positions or contact chrisc@mit.edu.

           

          RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

          Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu .

          Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

           

          FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

          Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

          The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

          Responsibilities:

          1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
          2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
          3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
          Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
           
          Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
           
          Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
           
          Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
           
          Availability: Spring 2015 graduates and other recent graduates.
           
          Citizenship: Must be a United States citizen to be eligible for the position.  
           
          Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
           
          Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
           
           

          ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

          Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

          We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

          To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

           

          POSTDOCTORAL FELLOW POSITION - JAIN LAB

          Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
           
          Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
           
          Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
           
           

          IMMUNEERING - POSITIONS AVAILABLE

          Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
           
          This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
           
          Pathway Biology
          Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
           
          Neurodegeneration and CNS Diseases
          Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
           
          Oncology
          Expertise in disease biology and data analysis for cancer research.
           
          Computational Biology
          Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
           
          Next Generation Sequencing (NGS)
          Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
           
          Machine Learning/Statistics (with Biological Applications)
          Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
           
          Responsibilities
          • Develop innovative algorithms and methods for analyzing data to identify biological insights
          • Interpret data from a biological and clinical perspective
          • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
          • Collaborate with colleagues to solve complex computational research problems
          • Present scientific material (written and oral) to diverse audiences
          Minimum Qualifications
          • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
          • Demonstrated experience developing novel algorithms to address complex scientific problems
          • Proven ability to work independently as well as contribute to larger initiatives
          • Effective English communication skills (both written and oral)
          • Proficient in at least one of R, Python, MATLAB, or a similar language.
          • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
          • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
          Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
          • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
          • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
          • Proficient in R
          • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
          For more information, please visit www.immuneering.com
           
          If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

           

          IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

          For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

          Visit IIE online at www.iie.org.
          Please contact the programs directly for additional information or with any questions you may have.
           
          A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

           
           

          Career Programs

           

          PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

          The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
          Dates for the remainder of the 201 Series are listed below:
          • September 22, 2015: Career Paths in Big DataRegister here.
          • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
          • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
           
          MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
           
          Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
           
          Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
           
          Web Presentations 
          We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
           
          MD Fellowship 
          We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
          Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
           
          Diversity & Inclusion at McKinsey 
          At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
           
                    

          GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

          For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

          The GECD Event calendar can be found here. 
           
           

          GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

          Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
           
           

          MIT CAREERBRIDGE

          There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

           

          Follow HST on Twitter Follow mit_hst on Twitter

           

           

          SHBT Thesis Defense - Rory D. Kirchner

          $
          0
          0

          Monday, August 31, 2015 – 1:00 PM
          MEEI, Room C605

          Automated, highly scalable RNA-seq analysis with applications

          RNA-sequencing is a sensitive method for inferring gene expression and provides additional information regarding splice variants, polymorphisms and novel genes and isoforms. Using this extra information greatly increases the complexity of an analysis and prevents novice investigators from analyzing their own data. The first chapter of this work introduces a solution to this issue. It describes a community-curated, scalable RNA-seq analysis framework for performing differential transcriptome expression, transcriptome assembly, variant and RNA-editing calling. It handles the entire stack of an analysis, from downloading and installing hundreds of tools, libraries and genomes to running an analysis that is able to be scaled to handle thousands of samples simultaneously. It can be run on a local machine, any high performance cluster or on the cloud and new tools can be plugged in at will. The second chapter of this work uses this software to examine transcriptome changes in the cortex of a mouse model of tuberous sclerosis with a neuron-specific knockout of Tsc1. We show that upregulation of the serotonin receptor Htr2c causes aberrant calcium spiking in the Tsc1 knockout mouse, and implicate it as a novel therapeutic target for tuberous sclerosis. The third chapter of this work investigates transcriptome regulation in the superior colliculus with prolonged eye closure. We show that while the colliculus undergoes long term anatomical changes with light deprivation, the gene expression in the colliculus is unchanged, barring a module of genes involved in energy production. We use the gene expression data to resolve a long-standing debate regarding the expression of dopamine receptors in the superior colliculus and found a striking segregation of the Drd1 and Drd2 dopamine receptors into distinct functional zones.


          Thesis Supervisor:
          Martha Constantine-Paton, PhD
          Title: Professor of Biology; Investigator, McGovern Institute for Brain Research, MIT

          Thesis Committee Chair:
          M. Christian Brown, PhD
          Title: Associate Professor of Otology and Laryngology, HMS; Eaton-Peabody Laboratories, MEEI

          Thesis Readers:
          M. Charles Liberman, PhD
          Title: Harold F. Schuknecht Professor of Otology and Laryngology, HMS; Eaton-Peabody Laboratories, MEEI

          Alvin Kho, PhD
          Title: Instructor in Pediatrics, BCH; Channing Division of Network Medicine, BWH

           

          Date and Time: 
          Monday, August 31, 2015 - 1:00pm to 3:00pm
          Location: 

          MEEI, Room C605

          MEMP - Thesis Defense - George J. Xu

          $
          0
          0

          Wednesday, September 9, 2015 – 9:00 AM
          HMS, NRB 350

          Comprehensive approaches to identifying the targets of natural and synthetic antibodies using microarray DNA synthesis and high-throughput sequencing

          The incredible flexibility and specificity of the humoral immune response is dependent on the highly diverse repertoire of naïve and affinity-matured antibodies. Utilizing and understanding the power of this response requires high-throughput approaches. This thesis describes three projects that use recent advances in DNA sequencing and synthesis to develop and apply methods to probe the diversity of these responses at unprecedented depth. Chapter 2 describes a synthetic antibody library designed for high-throughput sequencing assisted selection which enables rapid in vitro selection of antibodies that bind specifically to a target of interest by bypassing the need for laborious single-clone screening for specific binding. Chapter 3 describes a high-throughput assay for detection of antibodies against all known human viruses using immunoprecipitation and high-throughput sequencing of bacteriophage displaying a library of peptides tiling through the proteome of all known human viruses. And last, chapter 4 describes the use of immunoprecipitation and high-throughput sequencing of both bacteriophage displayed peptides from the human peptidome and ribosome displayed proteins from the human proteome to identify a novel subclass of patients with scleroderma with autoantibodies against the minor spliceosome complex. The work described in this thesis will enhance our ability to study and exploit the properties of antibodies and the humoral immune response.


          Thesis Supervisor:
          Stephen J. Elledge, PhD
          Title: Gregor Mendel Professor of Genetics and of Medicine, HMS

          Thesis Committee:
          George Church, PhD
          Title: Robert Winthrop Professor of Genetics, HMS

          Arlene Sharpe, MD, PhD
          Title: George Fabyan Professor of Comparative Pathology, HMS

          Wesley P. Wong, PhD
          Title: Assistant Professor of Biological Chemistry & Molecular Pharmacology and Pediatrics, HMS

          Date and Time: 
          Wednesday, September 9, 2015 - 9:00am to 11:00am
          Location: 

          HMS, NRB 350

          This week in HST - September 4, 2015 - Volume 17, Number 1

          $
          0
          0

          HST Community Notices
           

           

          Course Information &
          Academic Resources

          Conferences, Lectures & Seminars
           

          Student Opportunities
           

          Professional Opportunities
           

          Career Programs
           


          HST Community Notices

           

          HST FACULTY POSTER SESSION

          Students and faculty are warmly invited to participate in HST's annual Faculty Poster Session--designed to inform MD and PhD students about research opportunities and to allow faculty to recruit new students to their labs.  
           
          This year’s session will take place:
          • Thursday, September 24, 2015
          • 5-7pm 
          • Harvard Medical School, TMEC Atrium
            Refreshments will be served.
          Posters may take any form in a 4' by 4' format, ranging from an overview of an entire research portfolio to sample results of a recent research project.  
           
          Faculty and students may register a poster at https://hst.mit.edu/go/poster-session.

          If you have any questions, please write to hst-postersession@mit.edu.

           

          IMES DISTINGUISHED SPEAKER SERIES

          The IMES Distinguished Speaker Series invites you to attend a lecture by Dr. Helen Mayberg.
           
          "Targeted Therapeutic Modulation of Depression Circuits using Deep Brain Stimulation" 
          • Thursday, September 17, 2015
          • 4:30pm
          • E25-111
          Helen Mayberg, M.D. is Professor of Psychiatry, Neurology and Radiology and the Dorothy Fuqua Chair in Psychiatric Neuroimaging and Therapeutics at Emory University.  Over the last 25 years, her multi-disciplinary depression research team has worked to integrate cutting-edge imaging strategies, quantitative behavioral and psychophysiological metrics, and experimental treatment trials to define brain-based biomarkers that can optimize treatment selection for individual patients.  This work was foundational for the first studies of subcallosal cingulate deep brain stimulation for treatment resistant depression and remains the cornerstone of current studies to both refine and optimize DBS implementation and characterize network mechanisms mediating its antidepressant effects. Dr. Mayberg is a neurologist, trained at Columbia's Neurological Institute in New York, with fellowship training in nuclear medicine at Johns Hopkins. She is a member of the Institute of Medicine, among other honors, and participates in a wide variety of advisory and scientific activities across multiple fields in neuroscience.  
           
          Abstract:
          Deep Brain Stimulation is an emerging treatment strategy for patients with intractable depression with imaging playing a crucial role in the development, testing and refinement of the procedure. Multimodal modeling of structural and functional connections combined with real-time behavioral, autonomic and electrophysiological metrics are now used to more precisely identify the optimal target location as well as track long-term stimulation effects. Together these studies offer a unique perspective on critical pathways and mechanisms mediating antidepressant effects of DBS, and on the pathophysiology of treatment resistant depression more generally. 
           

           

          HST MEMP ALUMNI PROFILES

          Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
           

          HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

          Reality is merely an illusion, albeit a very persistent one.

                         --ALBERT EINSTEIN

          Give yours a quick check with hst-refs@mit.edu

          The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
           
          Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
           
           

          Course Information & Academic Resources

           
          SOME FALL COURSES TO CONSIDER
           
          HST courses of interest (full descriptions follow):
          • HST.140 Molecular Medicine 
          • HST.420 Principles and Practice of Assistive Technology (PPAT)
          • HST.508 Quantitative Genomics 
          • HST.518 Human Systems Engineering 
          • HST.565 Medical Imaging Sciences and Applications 
          • HST.580 Data Acquisition and Image Reconstruction in MRI 
          • HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis 
          • HST.590 Biomedical Engineering Seminar Series: Global Health
          • HST.720 Physiology of the Ear
          • HST.730 Molecular Biology of the Auditory System 
          • HST.973 Evaluating a Biomedical Business Concept 
          • HST.978 Healthcare Ventures 
          • HST.S52 Medical Device Design (Special Topics Course Number)

          Non-HST courses (full descriptions follow):

          • 2.S972 Developing Technologies for Music and Health (Special Topics Course Number)
          • 7.85 The Hallmarks of Cancer
          • 7.87 Protein Folding and Misfolding in Biology
          • 10.807  Innovation Teams
          • 15.378 Building an Entrepreneurial Venture: Advanced Tools and Techniques
           
          A complete list of HST courses can be found here: https://hst.mit.edu/academics/courses
          Full Subject Listings here: http://student.mit.edu/catalog/index.cgi
           
          ————————————————————
          HST.140/HST.141 Molecular Medicine 
          Prereq: 7.05 
          Units: 2-0-4 
          Lecture: T1-3 (MEC-104 & E25-119) Begins 9/15 at HMS. 
           
          Conducted as a seminar to study a variety of human diseases and the underlying molecular, genetic, and biochemical basis for the pathogenesis and pathophysiology of the disorders. Lectures by faculty and seminars conducted by students, with tutorials and supervision by faculty. Patients presented when feasible. Appropriate for students who have had a course in biochemistry and/or molecular biology. 
          I. M. London, G. Q. Daley, D. E. Cohen
           
          ————————————————————
          HST.420/6.811/2.S994 Principles and Practice of Assistive Technology 
          Undergraduate
          Prereq: Permission of instructor 
          Units: 2-4-6 
          Lecture: 1st mtg on Sept 9 at 2 pm. Room 32-144. Lecture: M2 (32-144) Lab: W2-5 (N52-337) 
          Poster attached
           
          Jointly being offered by MIT EECS, MechE, and IMES/HST, is centered around a design project in which student teams work closely with a person with a disability in the Cambridge area to design a device, piece of equipment, app, or other solution that helps them live more independently.  Over the course of the term, each team meets with its "client," iterates through multiple prototypes, and learns about the challenges and realities of designing technologies for people with disabilities.  See ppat.mit.edu or email ppat@mit.edu for more information.
          R. C. Miller, J. E. Greenberg, J. J. Leonard, G. Teo
           
          ————————————————————
          HST.508 Quantitative Genomics 
          Prereq: Permission of instructor 
          Units: 3-0-9 
          Lecture: MWF2.30-4 (56-191) 
           
          Provides in-depth quantitative understanding of evolutionary and population genetics, comparative and clinical genomics. Each module consists of a series of lectures, a journal club discussion of high impact publications, and lectures that provide clinical correlates. Homework assignments and final projects aim to develop understanding of genomic data from evolutionary principles. 
          L. Mirny
           
          ————————————————————
          HST.518/16.453/ESD.773 Human Systems Engineering 
          Prereq: 6.041, 16.09, or permission of instructor 
          Units: 3-1-8 
          Lecture: TR9.30-11 (37-212) 
           
          Provides a fundamental understanding of the human factors that must be considered in the design and engineering of complex aviation, space, and medical systems. Focuses on the derivation of human engineering design criteria from sensory, motor, and cognitive sources. Students, individually and in teams, apply design principles from topic areas including displays, controls, ergonomics, manual control, automation, basic experimental design, and human-computer interaction. Includes aviation, space, and medical incident case presentations and interactive projects. Graduate students also complete an additional research-oriented project with a final written report and oral presentation. 
          L. A. Stirling
           
          ————————————————————
          HST.565 Medical Imaging Sciences and Applications 
          Units: 3-0-9 
          Lecture: TR EVE (4.30-6 PM) (56-162) +final 
           
          Covers the biophysical, mathematical and instrumentation basics of positron emission tomography (PET), x-ray and computed tomography (CT), magnetic resonance imaging (MRI), and single photon emission tomography (SPECT). Topics include particles and photon interactions, nuclear counting statistics, gamma cameras, and computed tomography as it pertains to SPECT and PET (including PET-CT, PET-MR, and time-of-flight PET). Discusses the clinical applications of PET in molecular imaging of the brain, the heart, and cancer. Includes a practical demonstration of SPECT and PET-CT imaging at the Massachusetts General Hospital. Considers the ways in which these imaging techniques are rooted in physics, engineering, and mathematics as well as their respective role in anatomic and physiologic/molecular imaging. 
          G. El Fakhri, M. Normandin
           
          ————————————————————
          HST.580/6.556 Data Acquisition and Image Reconstruction in MRI 
          Prereq: 6.011 
          Units: 3-0-9 
          Lecture: TR11-12.30 (4-146) 
           
          Applies analysis of signals and noise in linear systems, sampling, and Fourier properties to magnetic resonance (MR) imaging acquisition and reconstruction. Provides adequate foundation for MR physics to enable study of RF excitation design, efficient Fourier sampling, parallel encoding, reconstruction of non-uniformly sampled data, and the impact of hardware imperfections on reconstruction performance. Surveys active areas of MR research. Assignments include Matlab-based work with real data. Includes visit to a scan site for human MR studies. 
          E. Adalsteinsson
           
          ————————————————————
          HST.583/9.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis 
          Prereq: 18.05; 18.06 or permission of instructor 
          Units: 2-3-7 
          Lecture: MW3 (4-231) Lab: M12.30-2 (1-115) Recitation: W2 (4-159) +final 
          Poster attached.
           
          Provides background necessary for designing, conducting, and interpreting fMRI studies in the human brain. Covers in depth the physics of image encoding, mechanisms of anatomical and functional contrasts, the physiological basis of fMRI signals, cerebral hemodynamics, and neurovascular coupling. Also covers design methods for stimulus-, task-driven and resting-state experiments, as well as workflows for model-based and data-driven analysis methods for data. Instruction in brain structure analysis and surface- and region-based analyses. Laboratory sessions include data acquisition sessions at the 3 Tesla MRI scanner at MIT and the Connectom and 7 Tesla scanners at the MGH/HST Martinos Center, as well as hands-on data analysis workshops. Introductory or college-level neurobiology, physics, and signal processing are helpful. 
          S. Whitfield-Gabrieli, J. Polimeni, A. Yendiki
           
          ————————————————————
          HST.720 Physiology of the Ear 
          Prereq: Permission of instructor 
          Units: 4-0-8 
          Lecture: 1st mtg Sept 9 at 4 pm. MEEI Eaton Peabody Library. (schedule determined at session)
           
          Physical and physiological mechanisms underlying the transduction and analysis of acoustic signals in the auditory periphery. Topics include the acoustics, mechanics, and hydrodynamics of sound transmission; the biophysical basis for cochlear amplification; the production of otoacoustic emissions; the physiology of hair-cell transduction and synaptic transmission; efferent feedback control; the analysis and coding of simple and complex sounds by the inner ear; and the physiological bases for hearing disorders. Based primarily on reading and discussions of original research literature. 
          J. J. Guinan, J. J. Rosowski, C. A. Shera
           
          ————————————————————
          HST.730 Molecular Biology of the Auditory System 
          Prereq: Biology (GIR) 
          Units: 3-0-9 
          Lecture: T EVE (4.30-7.30 PM) (EPL LIB) 
           
          Focuses on molecular approaches to cochlear development and function, based on readings and discussion of research literature. Lectures by course director and local experts in the field. Includes discussion of gene expression, cell fate determination, deafness mutations, stem cells and regeneration of the cochlea. 
          A. Edge
           
          ————————————————————
          HST.973/15.124 Evaluating a Biomedical Business Concept 
          Prereq: None 
          Units: 3-0-6 
          Lecture: W2.30-5.30 (E25-119) 
           
          Involves critical analysis of new biomedical business ideas. Inventors or principals of early stage companies present their ideas and provide background material including scientific papers and patents. Student teams interact with the companies, potential customers, other stakeholders and experts to develop a series of analyses concerning the critical issues. Company and student presentations supplemented by topic-specific lectures and presentations by biomedical entrepreneurs. Enrollment limited. 
          R. J. Cohen
           
          ————————————————————
          HST.978/15.367 Healthcare Ventures 
          Prereq: 15.910; 15.390 or 10.391 or 10.579 
          Units: 3-0-9 
          Lecture: T EVE (5-8 PM) (E51-315) 
           
          Focuses on entrepreneurship, with emphasis on startups bridging digital health and high-tech. Explores US and global macro trends and case studies. Features lectures by leading healthcare entrepreneurs and venture investors, and provides practical experience in networking through team projects. Evaluation based on team participation and assignments, including two team presentations. Video conference facilities provided to facilitate remote participation by Executive MBA and traveling students. Enrollment by application only. Enrollment by application only 
          M. Gray, Z. Chu
           
          ————————————————————
          HST.S52/2.75/6.525 Medical Device Design 
          Prereq: 2.72, 6.071, 6.115, or permission of instructor 
          Units: 3-0-9 
          Lecture: TR2.30-4 (3-442) 
           
          Application of mechanical and electrical engineering fundamentals to the design of medical devices that address clinical needs. Throughout the term, students work in small teams on a major project to translate a clinical challenge into a proof-of-concept prototype device. Students conduct user analysis, develop design specifications, and follow a structured process to cultivate creative designs and apply analytical techniques to optimize them. They deepen their understanding of art and intellectual property by researching prior representations. Develops practical skills in prototyping and testing as well as project management. Includes lectures, problem sets and exams that focus on design fundamentals. Instruction and practice in written and oral communication provided. Students taking graduate version complete additional assignments. Enrollment limited. 
          A. H. Slocum, C. G. Sodini
           
          ————————————————————
          2.S972 Developing Technologies for Music and Health
          Special seminar offered jointly with Berklee College of Music
          Units: 2-0-4
          Lecture: Fridays, 1pm to 3pm, 
          Please indicate your interest by completing our brief survey here: bit.ly/2s972
           
          Students will design and prototype devices that explore music's effects on health and brain functions (sleep, anxiety, athletic performance, and learning). Seminar will include literature review and presentation of current scientific evidence to support use of music to regulate health, plus research on technology for measuring health performance. Students will design a study to test hypotheses related to benefits of music, perform data-analysis of results from group research study, and present findings. Teams will develop and prototype product concepts. Seminar will include numerous special guest lectures. Limited enrollment, by permission of instructor. 
          Ken Zolot, in collaboration with Berklee's Institute for Creative Entrepreneurship, Berklee's Music Therapy Department, and The Sync Project.
           
          ————————————————————
          7.85 The Hallmarks of Cancer (New) 
          (Subject meets with 7.45) 
          Prereq: 7.06 or permission of instructor 
          Units: 4-0-8 
          Lecture: TR11-12.30 (E25-111) 
           
          Provides a comprehensive introduction to the fundamentals of cancer biology and cancer treatment. Topics include cancer genetics, genomics, and epigenetics; familial cancer syndromes; signal transduction, cell cycle control, and apoptosis; cancer metabolism; stem cells and cancer; metastasis; cancer immunology and immunotherapy; conventional and molecularly-targeted therapies; and early detection and prevention. Students taking graduate version complete additional assignments. 
          T. Jacks, M. Vander Heiden
           
          ————————————————————
          7.87 Protein Folding and Misfolding in Biology (New) 
          Prereq: 7.51 and 7.52; or permission of instructor 
          Units: 3-0-6 
          Credit cannot also be received for 7.88 
           
          Covers protein folding, misfolding, aggregation, and amyloid formation in the context of biological systems. Addresses topics such as chaperone structure and function, biofilm formation by bacteria, protein-folding diseases (including but not limited to Alzheimer's, Parkinson's, and Huntington's diseases), the process of therapeutics discovery for drugs and biologics. Features guest lectures and Skype discussions with international leaders in the field. Students present papers covering mutually agreed-upon topics of interest. 
          S. Lindquist
           
          ————————————————————
          10.807[J] Innovation Teams 
          (Same subject as 15.371[J])
          Prereq: 15.911 or permission of instructor
          Units: 4-4-4
          Fridays in 32-155. Lecture: W4.30-7, F9-11.30 (32-124)
           
          Students work in teams to develop commercialization strategies for innovative research projects generated in MIT laboratories. Projects cover critical aspects of commercialization, from selecting the target application and market for the technology to developing an intellectual property strategy and performing a competitive analysis. Instruction provided in communication and teamwork skills, as well as analysis of the challenges and benefits of technology transfer. Includes lectures, guest speakers, and extensive team coaching. Designed primarily for students in engineering, science, and management. Applications, resumes, and a brief statement of interest are required prior to registration.
          F. Murray, L. Perez-Breva, N. Afeyan
           
          ————————————————————
          15.378 Building an Entrepreneurial Venture: Advanced Tools and Techniques
          (Subject meets with 15.3781)
          Prereq: Permission of instructor
          Units: 3-1-8
          Lecture: M EVE (6-9 PM) (E40-160)
           
          Project-based class in which students use entrepreneurial techniques to build innovation-driven ventures in a time-compressed but robust setting. Applies fundamental concepts in greater depth and introduces tools and techniques. Students apply these concepts to specific venture-development projects. Designed to help students who want to prototype their potential new venture. Includes designing, developing, and testing the underlying product/service for the new venture. Students taking graduate version complete additional assignments. Application required; consult instructor.
          B. Aulet, J. Baum, E. Chen
           
           
           
          HARVARD CATALYST’S MEDICAL DEVICE DEVELOPMENT COURSE
           
          We are now accepting applications for Harvard Catalyst’s Medical Device Development course. This two-day course will provide an introduction to medical device innovation, development, and translation. We appreciate all of your efforts to promote this course to your academic and professional community.
           
          Medical Device Development
          • October 29-30, 2015
          • Sheraton Commander Hotel, Cambridge, MA
          • Apply by September 18, 2015!
          This course is tuition-free for Harvard-affiliated institutions.  
           
          For more information and a detailed description of Medical Device Development, please visit http://catalyst.harvard.edu/services/mdd/
           
          Contact us at med_devices@catalyst.harvard.edu with any questions.
           
          Joanna Chang, Education Program Developer, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
          Phone: 617-432-7113, Fax: 617-432-1560
           
          Casey Falla, Education Program Coordinator, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
          Phone: 617-432-7812, Fax: 617-432-1560
           
           
           
          CALLING FOR LIFE SCIENCES ENTREPRENEURS
           
          Do you have an idea you’d like to commercialize? Would you like to use Boston’s top scientific minds to help you build a business plan, get feedback from leading entrepreneurs & venture capitalists, and take the next step towards commercializing your biomedical brainchild?
           
          You are invited to submit a biomedical idea/invention for use in the 2015 Healthcare Innovation and Commercialization course. Submission will be reviewed based on commercialization potential, originality, and clinical relevance.
           
          PI’s, postdocs, and students are all encouraged to submit their inventions, which will be protected by NDA agreements from course participants.
           
          Please email your idea as a 1-page pdf document to harvardhic2015@gmail.com.

          Submitted ideas should include the following: 
          1) A brief description of yourself and your motivation to submit your idea
          2) Brief background on the problem you're trying to solve
          3) Description of your proposed solution
           
          Please visit http://www.harvardhic2015.com/curriculum.html for more information. 
          We look forward to hearing about your innovative ideas!
           
          HIC Team 2015
           
           
           
           
           

           


          Conferences, Lectures & Seminars

           

            WOMEN IN BIOTECH SYMPOSIUM

            • Friday, September 18, 2015
            • 1–5pm
            • Radcliffe Institute for Advanced Study, Harvard University
            Why are women underrepresented as leaders in the biotech industry?
             
            It’s a perplexing issue which warrants examination and discussion. Bringing together scientists, industry and venture capital leaders, and academics, this symposium will explore the divide between the large number of women who pursue advanced degrees in related scientific fields and their representation in leadership positions in biotech firms. Speakers will also share new research, experimentation, and promising models that may help industry, universities, government, and private capital improve the current system. Join us to gain a deeper understanding into this situation.
             
            Register online and view the full schedule: www.radcliffe.harvard.edu/event/2015-women-in-biotech-symposium
             
            Speakers:
            • Alison Wood Brooks, assistant professor of business administration, Harvard Business School
            • Victoria A. Budson, executive director, Women and Public Policy Program, Harvard Kennedy School
            • Daniel Carpenter, director of the social sciences program, Radcliffe Institute; Allie S. Freed Professor of Government in the Faculty of Arts and Sciences, Harvard University
            • Ann DeWitt, senior director of investments, Sanofi-Genzyme Bioventures
            • Deborah Dunsire, president and chief executive offer, Forum Pharmaceuticals
            • Robin Ely, Diane Doerge Wilson Professor of Business Administration and senior associate dean for Culture and Community, Harvard Business School
            • Monica C. Higgins, Kathleen McCartney Professor in Education Leadership, Harvard Graduate School of Education
            • Anula Jayasuriya, cofounder, Evolvence India Life Science Fund and India Life Science Fund II; founder, EXXclaim Capital
            • Janet Rich-Edwards, codirector of the science program, Radcliffe Institute; associate professor of medicine at Harvard Medical School; and associate professor in the department of epidemiology at the Harvard T.H. Chan School of Public Health
            • Laurel Smith-Doerr, professor of sociology and director of the Institute for Social Science Research, University of Massachusetts Amherst
            The event is free and open to the public.

             

            CROSS-INSTITUTIONAL TUMOR IMMUNITY RETREAT

            • Monday, November 16, 2015, 8:30am - Tuesday, November 17, 2015, 4:30pm
            • Joseph B. Martin Conference Center, HMS, 77 Avenue Louis Pasteur, Boston, MA 02115
            • Register at: tumorimmunity.org
            Attendance at the retreat is limited and registration will be made on a first-come first-serve basis.
             
            The event will bring together immunologists, cancer biologists, oncologists, computational biologists, and technologists from HMS and its hospitals, MIT, and the Broad Institute.
             
            The retreat will provide a forum to present the some of the work related to tumor immunity in our research community, and identify opportunities for collaborative research initiatives. 
             
            Program information can be found here.

            Questions?

             

            WINFOCUS CONFERENCE

            11th WINFOCUS World Congress on Ultrasound in Emergency and Critical Care Conference

            • October 22-2015
            • The Joseph B. Martin Conference Center at Harvard Medical School (77 Avenue Louis Pasteur, Boston, MA)
            World Interactive Network Focused On Critical Ultrasound (WINFOCUS) is a multi-specialty, international organization that is now a decade old and helps to promote point of care utilization and education throughout the world.
             
            It will be a great group of super-users, highly interactive and informational and lots of networking opportunities!

            There will be special sessions on medical student curriculum development and a competency assessment discussion panel which might be of interest too.
             
            More information is available at: http://www.winfocus2015.com/.
             
             

            27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM

            Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
            • Thursday, October 1, 2015
            • 2–5:30pm
            • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
            Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
             
            Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
            New York University Langone Medical Center
             
            Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
             
            Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
             

             

            HARVARD UNIVERSITY'S INAUGURAL FORUM ON POPULATION HEALTH EQUITY 

            Harvard University's Inaugural Forum on Population Health Equity, will be hosted by the Harvard T.H. Chan School of Public Health, with generous support from the Aetna Foundation.

            • September 10-11, 2015 
            • Martin Conference Center, in the Harvard Longwood Area, of Boston, MA.
            We hope you will join us for the meeting, which will convene over 450 academics and professionals to network and hear domestic and global public health leaders address a range of population health equity issues, from racial inequities to macro-economic shocks.
             
            Registration for the meeting is free, but seats are limited. We encourage you to register today through the Forum website: http://tinyurl.com/PopHealthEquityForumOnline or Facebook page: http://www.Facebook.com/PopHealthEquity
             
            In the meantime, we hope you will encourage your colleagues, students and staff members to attend, as well as friend us Facebook and follow us on Twitter (@PopHealthEquity). 
             
            The latest agenda (also available online at http://tinyurl.com/UpdatedForumAgenda), flyer, and promotional banner are attached for your reference, and to share with others. You can access additional information about our diverse faculty of speakers here: http://tinyurl.com/ForumSpeakers, as well as watch special Forum welcome messages here: https://youtu.be/O9TAb4PtPfk and here: https://youtu.be/e4NDXRli6fQ

             

            LEADINGAGE HACKFEST

            • October 30-November 1, 2015 
            • UMass, Boston

            LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

            A Youtube video about the event is available here.   

            Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

             

            PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

            • October 29-30, 2015 
            • Seaport Hotel & World Trade Center, Boston
            This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
             
            The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
             
            Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
             
            For more information and to register, please visit the Symposium website:

             

            MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

            Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

            But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
             
            At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
             
            More information and events from Medtech Boston is available here.
             
             

            MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

            The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

            Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
             
            Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
             
            Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
             
             

            HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

            The HMS JPNM offers a weekly seminar series from September through May/June.
             
            Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
             
            S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
             
            If you would like to be added to the weekly email distribution list for the lectures, please contact:
            Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
             
            Upcoming Seminars:
             
            Stay tuned for Fall 2015 seminar information.

             
            BRAINMAP SEMINARS

            Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
             
            Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
             
            To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
             
            There are no more Brainmap regular seminars scheduled for the summer.
             
             
             
             

            Student Opportunities
             

            MUSIC ENSEMBLES OPEN TO GRADUATE STUDENTS AT MIT

            There are a number of opportunities for graduate students to participate in music ensembles at MIT:

            • MIT Concert Choir
            • MIT Chamber Chorus
            • MIT Vocal Jazz Ensemble
            • Emerson Program for Private Study
            • MIT Symphony Orchestra
            • MIT Wind Ensemble
            • MIT Chamber Music Society
            • CMS Jazz Combos
            • MIT Festival Jazz Ensemble
            • MIT Gamelan Galak Tika
            • Rambax MIT

            Information about auditioning for these performing groups can be found here.

            Auditions are being held now!

             

            PATEXIA - APPLIED RESEARCH OPPORTUNITIES FOR ENGINEERING STUDENTS

            What we do…

            Patexia is a Los Angeles-based startup that uses crowdsourcing to solve engineering and innovation challenges for some of the largest technology companies and research-oriented organizations in the world. We were recently awarded a contract through the NASA Tournament Lab and we are looking for talented undergraduate and graduate engineering students to join our network as problem solvers and campus ambassadors. 
             
            Applied research opportunities…
             
            Technical Problem Solver
             
            The strength of Patexia’s crowdsourcing model comes from the global community of over 10,000 technical problem solvers and subject matter experts behind it. By joining our professional network as a student member you will have the chance to interface with top companies and research organizations in your field as you develop innovative solutions to real world challenges. Throughout the process you will be collaborating with classmates, professors, and experts from around the globe as you compete against teams from other US and international universities for bragging rights and cash prizes.
             
            Campus Ambassador
             
            As a bridge between industry-driven problems and university-based solutions, we need to work with the very best in order to exceed the expectations of clients such as NASA and Cedars-Sinai Medical Center. The Patexia campus ambassador program is built around well-connected engineering students who can not only help us solve technical problems, but can share their experience with classmates, friends, and professors to help expand our reach. Campus ambassadors will regularly meet and train with the Patexia team and, in addition to compensation for meeting defined recruitment goals, ambassadors will be invited to relevant networking events and be given the opportunity to directly connect with important industry contacts.
             
            How you can get involved...
             
            If you are interested in collaborating with Patexia as a problem solver, campus ambassador, or both please contact us at ambassador@patexia.com. You can also read more about the perks of the ambassador program here on Patexia.
             
             

            HARVARD HEALTH POLICY REVIEW - CALL FOR STUDENT ARTICLES

            HHPR would like to invite you to contribute an article to our Student Contributions section.

            Our Student Contributions articles engage in various topics and issues in health policy from different perspectives. The theme for the Fall 2015 issue is “Precision Medicine.” With the launch of the Precision Medicine Initiative earlier this year by President Obama, the growing recognition of precision medicine by clinicians, patients, researchers, and policy makers reflects the accelerating emergence of this new approach in the field of medicine. We are currently soliciting articles that address the broad implications, opportunities, as well as challenges related to this new initiative. 
             
            The submission deadline for the Spring 2015 issue is September 15, 2015.
             
            Submission guidelines for our publication can be found here.
             
            Please do not hesitate to contact us at hhpr.harvard@gmail.com or hhprstudentcontributions@gmail.com if you have any questions or concerns.

             

            GRADRAT WINE & CHEESE ORIENTATION WELCOME 

            • Friday, September 11, 2015 
            • 5-7pm 
            • Walker Memorial 
             
                        • Come enjoy wine, fruits and cheese!
                        • Free givewaways
                        • Raffles for a free gradrat and 5 $50 discounts
                        • First 200 rings sold will receive a $25 discount

             

            MIT ENGLISH AS A SECOND LANGUAGE VOLUNTEERS NEEDED

            The MIT English as a Second Language Program for Service Employees is looking for volunteers to tutor night shift employees for 1-2 hrs/wk or to serve as substitutes as needed for the Fall semester that runs from September 28 - December 11, 2015.
             
            No experience is required, just a good command of English and an interest in helping individuals whose first language is not English. The goals of the program are to build student’s confidence, to help them become more productive in their jobs, and to perhaps open up further opportunities for advancement.
             
            Tutoring takes place on Tuesdays and Thursdays from 11pm - midnight beginning September 28.

            This is an opportunity to make a real and positive difference..
             
            Please contact esl-admins@mit.edu for details.

             

            MIT VETERANS OUTREACH

            Veteran Students, do you know . . .
             
               there are two MIT veteran student clubs.
               that there is a committee dedicated to veterans outreach comprised of faculty, staff and students.
               that room 50-010 is a space exclusively for veteran students.
               
            Is this only United States veterans?   No, we serve all students who are veterans.
            Interested in knowing more, please contact Mary Kathryn, extension 4.7824 or mjuskiew@mit.edu.

             

            APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

            Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
            For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

             

            UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

            Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
            nomination.
             
            More information may be found here. 
             
             
            GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

            Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

            Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
            community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

            Open positions are as follows:

            • Institute Community and Equity Office (one position open for 2015-16)
            • Language Conversation Excahnge (position open for 2015-16)
            Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
            We are accepting applications now and will fill positions on a rolling basis.
            Receive a monthly stipend while you gain experience.  Apply now!
            Questions? Contact Heather Konar (konar@mit.edu)

             

            COMMUNITY SERVICE WEEKLY BULLETIN

            At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
            Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
             
            As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
            efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
             
            Sign up for the weekly Community Service Bulletin of Events and Programs here.
            News and upcoming events are posted on the homepage.

             

             


            Professional Opportunities

             

            L.E.K. CONSULTING - PHD & MD RECRUITING

            Company Description
            L.E.K. Consulting is a global management consulting firm that uses deep industry expertise and rigorous analysis to help business leaders achieve practical results with real impact. We are uncompromising in our approach to helping clients consistently make better decisions, deliver improved business performance and create greater shareholder returns. The firm advises and supports global companies that are leaders in their industries — including the largest private and public sector organizations, private equity firms and emerging entrepreneurial businesses. Founded more than 30 years ago, L.E.K. employs more than 1,000 professionals across the Americas, Asia-Pacific and Europe. For more information, go to www.lek.com

             
            Life Sciences Specialist
            L.E.K. Life Sciences Specialists have their Ph.D.s in a science field and are from the top programs at leading universities. Life Sciences Specialists are hired for their expertise in the life sciences field, which has proved invaluable to our clients.
             
            Specific responsibilities include:
            • Gathering primary and secondary data on markets, competitors, and customers through database and Internet searches, market research and other commercial reports, internal client data, and telephone and in-person interviews.
            • Leveraging scientific background and transferring specific knowledge base to the team in order to develop rigorous solutions to client issues.
            • Developing rigorous strategic and financial analysis that will be utilized to determine L.E.K.’s recommendation to the client. Examples include developing a spreadsheet model of market growth and competitor share, developing a valuation model for a company or product using discounted cash flow analysis, testing customer sensitivity to product attributes using adaptive conjoint analysis, or determining probability distributions of acquisition value.
            • Collaborating with project team members to derive trends, conclusions, and recommendations based upon the analysis. A Life Sciences Specialist must transform what he or she has learned into thoughtful insights regarding the client’s strategic direction.
            • Making L.E.K. an enjoyable and rewarding place to work. This includes coaching colleagues and transferring skills, offering constructive advice, and contributing to the social environment of the office.
            Application Requirements
            L.E.K. does not have a rigid checklist of qualities a potential Life Sciences Specialist must possess. Rather, our recruiting experience has shown that outstanding academic achievement, comfort with quantitative analysis, significant professional experiences, notable extracurricular interests, and demonstrated leadership and initiative are excellent preparation for a position within the Life Sciences Specialist Program at L.E.K. Consulting.
             
            Interested applicants should apply online through our website at www.lek.com/careers by September 16, 2015.
             
            L.E.K Consulting is an Equal Opportunity Employer

             

            PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE: OPEN FACULTY POSITIONS

            The School of Engineering, the School of Medicine and the Faculty of Biological Sciences of the Pontificia Universidad Católica de Chile invite applications for two full-time faculty positions in the areas of Biomedical Devices, and Bioinformatics and Computational Biology. The candidate will join other full-time faculty and several part-time appointments in the recently established Institute for Biological and Medical Engineering, dedicated to research and teaching in the areas of Biomedical Imaging and Modelling, Bioinformatics, Systems Biology, Synthetic Biology, Biotechnology, Biomechanics, and Biomaterials.

             

            VL34 - SCIENTIST/SENIOR SCIENTIST IN MOLECULAR BIOLOGY

            VL34, Inc. has an immediate opening for a Scientist/Senior Scientist in molecular biology.  VL34 is an early-stage startup in Cambridge, MA using cutting-edge molecular techniques to help create a novel category of fertility treatment. VL34 was founded by VentureLabs, a unit of Flagship Ventures which has launched over 25 breakthrough companies including Seres Therapeutics, Symbiota, Pronutria, and Moderna Therapeutics. 

            Position Summary
            VL34, Inc. is seeking an exceptional, highly motivated Scientist/Senior Scientist to play a key role in the company’s efforts to build a high-throughput platform to identify molecular targets with applications in the fertility field.  As part of the early team of scientists at VL34, this individual will have wide-ranging responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative group.
             
            Key Qualifications
            Ph.D. in Biology or a related field, with or without postdoc or industry experience 
            Ability to think critically and creatively as part of a fast-paced research team
            Proven hands-on experience with standard molecular biology techniques.
            Especially preferred to have experience with one or more of:
            oCustom library preparation for high-throughput sequencing, single cell or low-input detection
            oProtein engineering, library-based display technologies (yeast, phage), in vitro directed evolution and selection
            Enthusiasm for pushing the frontiers of conventional techniques and comfort in venturing beyond one’s area of expertise
            Great hands in the laboratory and resourceful when starting new techniques from scratch
            Excellent collaboration, communication and interpersonal skills

            Responsibilities
            The successful candidate will work closely with an interdisciplinary team as well as independently to design and execute experiments that support research activities and project goals
            Quickly implement state-of-the-art techniques in new biological models
            Identify modifications to iteratively improve protocols
            Analyze data and help identify molecular targets and follow-up experiments
            Participate in various aspects of the company from establishing collaborations to writing patents to long-term planning
             
            Compensation
            A competitive overall compensation package including: competitive base salary, bonus potential and stock options.
             
            Contact Information
            To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Brian at VL34Jobs@gmail.com.

             

            PURETECH - SENIOR ANALYST

            About PureTech

            PureTech is a science-driven healthcare company, seeking to solve some of today’s toughest health challenges through disruptive approaches. Based in Boston, PureTech has a network of more than 50 experts across multiple disciplines – from entrepreneurs to world-renowned scientists – giving PureTech access to potentially groundbreaking science and technological innovations. PureTech is problem-focused and solution-agnostic, looking beyond traditional disciplines and approaching healthcare problems from different perspectives. Focusing on areas of significant unmet medical need, PureTech evaluates more than 650 ideas per year, prioritizing, testing and selecting what it believes to be the most scientifically and commercially promising concepts to advance.
             
            JOB DESCRIPTION:
            The Senior Analyst will get hands-on experience in entrepreneurship, participate in sourcing and due diligence of technologies and support PureTech's Innovations and team members. This includes:
            Ideation and business planning for next generation technologies
            Conducting strategic analyses & market opportunity assessments
            Undertaking project management & operations of innovations including development of cutting edge technologies
            Participating in analysis and development of intellectual property
            Preparing compelling communication materials, including presentations, for key external stakeholders
             
            QUALIFICATIONS:
            Creativity, smarts & initiative
            PhD in one of the following disciplines from a top tier institution: engineering, physics, computer science, or a life sciences related field
            Business experience is a plus but not required
            Strong presentation and communication skills; candidate should feel comfortable presenting to groups
             
            LOCATION: Boston, Massachusetts
            The position is full time with a competitive salary and benefits. This is a unique opportunity to join one of the most innovative companies in healthcare while getting hands-on startup experience in our Innovations. Please send your resume and cover letter to careers@puretechhealth.com. Be sure to indicate the Senior Analyst Position in the subject of your email.  (E-mail applications sent directly to PureTech staff will not be considered)

             

            POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

            A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

            Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

             

            RESEARCH AND DEVELOPMENT SCIENTIST POSITION

            Aptitude Medical Systems Inc. – Santa Barbara, CA

            Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
             
            Summary
            There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
             
            Why Choose Aptitude
            We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
            We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
             
            Responsibilities
            The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
            • Develop, test, and optimize aptamers, assays and other products
            • Design and execute experiments; process, analyze, and interpret experimental results and data
            • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
            • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
            • Develop original solutions to problems and create new experimental strategies
            • Help set project goals, milestones and continuously track progress and success
            • Prioritize and manage technical tasks for concurrent projects
            • Help and support other project teams or groups when needed
             
            Knowledge, Skills, and Abilities Required
            The four fundamental characteristics that we need on the team are:
            • Willingness to take on any responsibility to enable the team to achieve success
            • A sense of urgency and ability to achieve time-sensitive milestones
            • Persistence to work through challenges and unlock both systematic and creative solutions 
            • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
             
            In addition, we look for the following skills and abilities in top candidates:
            • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
            • Meticulous attention to detail, executing with high accuracy and reproducibility
            • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
            • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
            • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
            • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
             
            Education/Experience Required
            Different combinations of experience and educations will be considered for qualification of this position:
            • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
            • At least four years of work-related experience in a relevant laboratory environment
            • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

             
            PORTAL INSTRUMENTS POSITION AVAILABLE

            Lead Firmware Engineer
             
            About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
             
            Working at Portal Instruments:
            • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
            • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
            • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
            Role and Responsibilities:
            • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
            • Design, build, debug, and optimize the device’s firmware
            • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
            • Integrate with a team of firmware, software, and control engineers.
            • Design, build, debug, and optimize firmware
            • Evaluate system performance by designing, executing, and documenting experimental plans.
            • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
            • Support electrical compliance testing.
            • Support the manufacture and testing of electronic assemblies by providing test procedures
            • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
            Required Skills and Experience:
            • Development of efficient microcontroller firmware in C, preferably ARM.
            • Familiarity with quality system requirements for medical software system development.
            • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
            • Experience with high-bandwidth motion control.
            • Sensor synthesis / sensor fusion.
            • Familiarity with electronic hardware design.
            • Automated integration testing of firmware.
            Qualifications:
            • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
            • 5+ years of experience in commercial development and/or validation.
            • Experience with medical products development and FDA or related product approvals a plus.
            • Outstanding software engineering and design skills.
            • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
            • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
            • Ability to work independently in a start-up environment.
            Salary commensurate with experience; potential equity participation.
             
            To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
             

            10X GENOMICS - POSITIONS AVAILABLE

            10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

            Applications Scientist: Computational Biology
            10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
             
            Computational Biologist: Algorithm Development
            10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
             
            Computer Scientist: Algorithm Development
            Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
             
            We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

            Data Scientist
            10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
             
            For more information about the company and to see the job listings, visit: 10xgenomics.com/company

            To apply for a position please contact jobs@10xgenomics.com

             

            POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

            Graduate Research Assistant: Contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG, setg.mit.edu), has the potential to provide the first direct evidence for life on Mars and on icy moons, as well as enable diverse environmental and clinical applications. Opportunity to 1) develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches, to 2) design, develop, and validate the instrument in the lab, and in the field at terrestrial analogs of Mars or other extreme environments. Responsibilities also include communicating results to the scientific community through publications and presentations.
             
            This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. You will work closely with the Science PI, Christopher Carr (carrlab.org), in association with the project PI Maria Zuber at MIT, the MGH Institutional PI Gary Ruvkun, and other academic and industrial partners.
             
            Job Requirements
            REQUIRED: Undergraduate degree in highly relevant field; strong analytical and problem solving skills. You must be highly motivated, technically excellent, able to work independently and contribute to an interdisciplinary team, and have excellent communication and interpersonal skills. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills highly valued.
             
            How to Apply
            Please send a CV and cover letter with the name and email of three references to chrisc@mit.edu with “SETG Research Assistant Application” in the subject line.

             

            RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

            Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu.

            Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

             

            FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

            Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

            The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

            Responsibilities:

            1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
            2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
            3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
            Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
             
            Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
             
            Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
             
            Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
             
            Availability: Spring 2015 graduates and other recent graduates.
             
            Citizenship: Must be a United States citizen to be eligible for the position.  
             
            Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
             
            Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
             
             

            ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

            Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

            We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

            To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

             

            POSTDOCTORAL FELLOW POSITION - JAIN LAB

            Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
             
            Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
             
            Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
             
             

            IMMUNEERING - POSITIONS AVAILABLE

            Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
             
            This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
             
            Pathway Biology
            Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
             
            Neurodegeneration and CNS Diseases
            Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
             
            Oncology
            Expertise in disease biology and data analysis for cancer research.
             
            Computational Biology
            Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
             
            Next Generation Sequencing (NGS)
            Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
             
            Machine Learning/Statistics (with Biological Applications)
            Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
             
            Responsibilities
            • Develop innovative algorithms and methods for analyzing data to identify biological insights
            • Interpret data from a biological and clinical perspective
            • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
            • Collaborate with colleagues to solve complex computational research problems
            • Present scientific material (written and oral) to diverse audiences
            Minimum Qualifications
            • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
            • Demonstrated experience developing novel algorithms to address complex scientific problems
            • Proven ability to work independently as well as contribute to larger initiatives
            • Effective English communication skills (both written and oral)
            • Proficient in at least one of R, Python, MATLAB, or a similar language.
            • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
            • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
            Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
            • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
            • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
            • Proficient in R
            • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
            For more information, please visit www.immuneering.com
             
            If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

             

            IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

            For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

            Visit IIE online at www.iie.org.
            Please contact the programs directly for additional information or with any questions you may have.
             
            A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

             
             

            Career Programs

             

            GECD FALL CAREER FAIR PREP EVENTS

            MIT Global Education & Career Development (GECD) Career Services offers a number of special events, panels, workshops and extended drop-in hours to help you prepare for the Fall Career Fair on Friday, September 25, 2015.

            Opportunities to prepare for the Fall Career Fair can be found here.

             

            PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

            The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
            Dates for the remainder of the 201 Series are listed below:
            • September 22, 2015: Career Paths in Big DataRegister here.
            • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
            • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
             
            MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
             
            Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
             
            Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
             
            Web Presentations 
            We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
             
            MD Fellowship 
            We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
            Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
             
            Diversity & Inclusion at McKinsey 
            At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
             
                      

            GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

            For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

            The GECD Event calendar can be found here. 
             
             

            GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

            Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
             
             

            MIT CAREERBRIDGE

            There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

             

            Follow HST on Twitter Follow mit_hst on Twitter

             

             

            Turbocharging Medical Translation

            $
            0
            0

            Most medical researchers focus tightly on a narrow set of diseases or technologies. Jeff Karp looks instead across a broad smorgasbord of medical issues where innovative bioengineering can make a big difference in a relatively small amount of time.

            “In my laboratory, we bring together people from diverse backgrounds,” says Karp, associate professor at Harvard Medical School and Brigham and Women’s Hospital, and affiliate faculty at the Harvard-MIT Division of Health Sciences and Technology. “We have chemical engineers, immunologists, basic biologists, materials scientists, polymer engineers and clinicians. We work very collaboratively, and we like to pick problems where there’s opportunity for translation in the near future.”

            These multidisciplinary teams at the Karp Laboften turn to nature for inspiration. “Evolution is the best problem solver, with millions of years of research and development,” Karp remarks. “Every living thing is here today because it has solved an incredible number of challenges. We’ve tried to overcome challenges on translational projects by turning to creatures such as porcupines, parasitic worms, cactus needles, slugs, snails and spider webs. All of these examples in nature have provided insight that we would never have had by just staying inside of the lab.”

            Date: 
            Friday, September 4, 2015

            This week in HST - September 11, 2015 - Volume 17, Number 2

            $
            0
            0

            HST Community Notices
             

             

            Course Information &
            Academic Resources

            Conferences, Lectures & Seminars
             

            Student Opportunities
             

            Professional Opportunities
             

            Career Programs
             


            HST Community Notices

             

            HST FACULTY POSTER SESSION

            Students and faculty are warmly invited to participate in HST's annual Faculty Poster Session--designed to inform MD and PhD students about research opportunities and to allow faculty to recruit new students to their labs.  
             
            This year’s session will take place:
            • Thursday, September 24, 2015
            • 5-7pm 
            • Harvard Medical School, TMEC Atrium
              Refreshments will be served.
            Posters may take any form in a 4' by 4' format, ranging from an overview of an entire research portfolio to sample results of a recent research project.  
             
            Faculty and students may register a poster at https://hst.mit.edu/go/poster-session.

            If you have any questions, please write to hst-postersession@mit.edu.

             

            IMES DISTINGUISHED SPEAKER SERIES

            The IMES Distinguished Speaker Series invites you to attend a lecture by Dr. Helen Mayberg.
             
            "Targeted Therapeutic Modulation of Depression Circuits using Deep Brain Stimulation" 
            • Thursday, September 17, 2015
            • 4:30pm
            • E25-111
            Helen Mayberg, M.D. is Professor of Psychiatry, Neurology and Radiology and the Dorothy Fuqua Chair in Psychiatric Neuroimaging and Therapeutics at Emory University.  Over the last 25 years, her multi-disciplinary depression research team has worked to integrate cutting-edge imaging strategies, quantitative behavioral and psychophysiological metrics, and experimental treatment trials to define brain-based biomarkers that can optimize treatment selection for individual patients.  This work was foundational for the first studies of subcallosal cingulate deep brain stimulation for treatment resistant depression and remains the cornerstone of current studies to both refine and optimize DBS implementation and characterize network mechanisms mediating its antidepressant effects. Dr. Mayberg is a neurologist, trained at Columbia's Neurological Institute in New York, with fellowship training in nuclear medicine at Johns Hopkins. She is a member of the Institute of Medicine, among other honors, and participates in a wide variety of advisory and scientific activities across multiple fields in neuroscience.  
             
            Abstract:
            Deep Brain Stimulation is an emerging treatment strategy for patients with intractable depression with imaging playing a crucial role in the development, testing and refinement of the procedure. Multimodal modeling of structural and functional connections combined with real-time behavioral, autonomic and electrophysiological metrics are now used to more precisely identify the optimal target location as well as track long-term stimulation effects. Together these studies offer a unique perspective on critical pathways and mechanisms mediating antidepressant effects of DBS, and on the pathophysiology of treatment resistant depression more generally. 

             

            GHMHI/SHASS/IMES - GUEST LECTURE

            "Dissolve: A Modest Proposal to Rethink Global Health"

            • Friday, September 18, 2015
            • 10am - 12pm
            • E25-401
            This event will feature Didier Fassin, from the Institute for Advanced Study, who will present an original talk entitled, "Dissolve: A Modest Proposal to Rethink Global Health." Coffee and pastries will be served. We hope you will be able to join us!
                
            This talk is free and open to the public.
             
            For additional information:
            Please visit the Global Health and Medical Humanities Initiative Website (http://ghmhi.mit.edu) or contact Brittany Peters via email at bapeters@mit.edu
             
            Sponsored by Global Health and Medical Humanities Initiative, Anthropology Program, IMES

             
            HST MEMP ALUMNI PROFILES

            Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
             

            HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

            Reality is merely an illusion, albeit a very persistent one.

                           --ALBERT EINSTEIN

            Give yours a quick check with hst-refs@mit.edu

            The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
             
            Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
             
             

            Course Information & Academic Resources

             
            SOME FALL COURSES TO CONSIDER
             
            HST courses of interest (full descriptions follow):
            • HST.140 Molecular Medicine 
            • HST.420 Principles and Practice of Assistive Technology (PPAT)
            • HST.508 Quantitative Genomics 
            • HST.518 Human Systems Engineering 
            • HST.565 Medical Imaging Sciences and Applications 
            • HST.580 Data Acquisition and Image Reconstruction in MRI 
            • HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis 
            • HST.590 Biomedical Engineering Seminar Series: Global Health
            • HST.720 Physiology of the Ear
            • HST.730 Molecular Biology of the Auditory System 
            • HST.973 Evaluating a Biomedical Business Concept 
            • HST.978 Healthcare Ventures 
            • HST.S52 Medical Device Design (Special Topics Course Number)

            Non-HST courses (full descriptions follow):

            • 2.S972 Developing Technologies for Music and Health (Special Topics Course Number)
            • 7.85 The Hallmarks of Cancer
            • 7.87 Protein Folding and Misfolding in Biology
            • 10.807  Innovation Teams
            • 15.378 Building an Entrepreneurial Venture: Advanced Tools and Techniques
            • MAS.S62 Engineering Health: Understanding and Designing Affordable Health Diagnostics
             
            A complete list of HST courses can be found here: https://hst.mit.edu/academics/courses
            Full Subject Listings here: http://student.mit.edu/catalog/index.cgi
             
            ————————————————————
            HST.140/HST.141 Molecular Medicine 
            Prereq: 7.05 
            Units: 2-0-4 
            Lecture: T1-3 (MEC-104 & E25-119) Begins 9/15 at HMS. 
             
            Conducted as a seminar to study a variety of human diseases and the underlying molecular, genetic, and biochemical basis for the pathogenesis and pathophysiology of the disorders. Lectures by faculty and seminars conducted by students, with tutorials and supervision by faculty. Patients presented when feasible. Appropriate for students who have had a course in biochemistry and/or molecular biology. 
            I. M. London, G. Q. Daley, D. E. Cohen
             
            ————————————————————
            HST.420/6.811/2.S994 Principles and Practice of Assistive Technology 
            Undergraduate
            Prereq: Permission of instructor 
            Units: 2-4-6 
            Lecture: 1st mtg on Sept 9 at 2 pm. Room 32-144. Lecture: M2 (32-144) Lab: W2-5 (N52-337) 
            Poster attached
             
            Jointly being offered by MIT EECS, MechE, and IMES/HST, is centered around a design project in which student teams work closely with a person with a disability in the Cambridge area to design a device, piece of equipment, app, or other solution that helps them live more independently.  Over the course of the term, each team meets with its "client," iterates through multiple prototypes, and learns about the challenges and realities of designing technologies for people with disabilities.  See ppat.mit.edu or email ppat@mit.edu for more information.
            R. C. Miller, J. E. Greenberg, J. J. Leonard, G. Teo
             
            ————————————————————
            HST.508 Quantitative Genomics 
            Prereq: Permission of instructor 
            Units: 3-0-9 
            Lecture: MWF2.30-4 (56-191) 
             
            Provides in-depth quantitative understanding of evolutionary and population genetics, comparative and clinical genomics. Each module consists of a series of lectures, a journal club discussion of high impact publications, and lectures that provide clinical correlates. Homework assignments and final projects aim to develop understanding of genomic data from evolutionary principles. 
            L. Mirny
             
            ————————————————————
            HST.518/16.453/ESD.773 Human Systems Engineering 
            Prereq: 6.041, 16.09, or permission of instructor 
            Units: 3-1-8 
            Lecture: TR9.30-11 (37-212) 
             
            Provides a fundamental understanding of the human factors that must be considered in the design and engineering of complex aviation, space, and medical systems. Focuses on the derivation of human engineering design criteria from sensory, motor, and cognitive sources. Students, individually and in teams, apply design principles from topic areas including displays, controls, ergonomics, manual control, automation, basic experimental design, and human-computer interaction. Includes aviation, space, and medical incident case presentations and interactive projects. Graduate students also complete an additional research-oriented project with a final written report and oral presentation. 
            L. A. Stirling
             
            ————————————————————
            HST.565 Medical Imaging Sciences and Applications 
            Units: 3-0-9 
            Lecture: TR EVE (4.30-6 PM) (56-162) +final 
             
            Covers the biophysical, mathematical and instrumentation basics of positron emission tomography (PET), x-ray and computed tomography (CT), magnetic resonance imaging (MRI), and single photon emission tomography (SPECT). Topics include particles and photon interactions, nuclear counting statistics, gamma cameras, and computed tomography as it pertains to SPECT and PET (including PET-CT, PET-MR, and time-of-flight PET). Discusses the clinical applications of PET in molecular imaging of the brain, the heart, and cancer. Includes a practical demonstration of SPECT and PET-CT imaging at the Massachusetts General Hospital. Considers the ways in which these imaging techniques are rooted in physics, engineering, and mathematics as well as their respective role in anatomic and physiologic/molecular imaging. 
            G. El Fakhri, M. Normandin
             
            ————————————————————
            HST.580/6.556 Data Acquisition and Image Reconstruction in MRI 
            Prereq: 6.011 
            Units: 3-0-9 
            Lecture: TR11-12.30 (4-146) 
             
            Applies analysis of signals and noise in linear systems, sampling, and Fourier properties to magnetic resonance (MR) imaging acquisition and reconstruction. Provides adequate foundation for MR physics to enable study of RF excitation design, efficient Fourier sampling, parallel encoding, reconstruction of non-uniformly sampled data, and the impact of hardware imperfections on reconstruction performance. Surveys active areas of MR research. Assignments include Matlab-based work with real data. Includes visit to a scan site for human MR studies. 
            E. Adalsteinsson
             
            ————————————————————
            HST.583/9.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis 
            Prereq: 18.05; 18.06 or permission of instructor 
            Units: 2-3-7 
            Lecture: MW3 (4-231) Lab: M12.30-2 (1-115) Recitation: W2 (4-159) +final 
            Poster attached.
             
            Provides background necessary for designing, conducting, and interpreting fMRI studies in the human brain. Covers in depth the physics of image encoding, mechanisms of anatomical and functional contrasts, the physiological basis of fMRI signals, cerebral hemodynamics, and neurovascular coupling. Also covers design methods for stimulus-, task-driven and resting-state experiments, as well as workflows for model-based and data-driven analysis methods for data. Instruction in brain structure analysis and surface- and region-based analyses. Laboratory sessions include data acquisition sessions at the 3 Tesla MRI scanner at MIT and the Connectom and 7 Tesla scanners at the MGH/HST Martinos Center, as well as hands-on data analysis workshops. Introductory or college-level neurobiology, physics, and signal processing are helpful. 
            S. Whitfield-Gabrieli, J. Polimeni, A. Yendiki
             
            ————————————————————
            HST.720 Physiology of the Ear 
            Prereq: Permission of instructor 
            Units: 4-0-8 
            Lecture: 1st mtg Sept 9 at 4 pm. MEEI Eaton Peabody Library. (schedule determined at session)
             
            Physical and physiological mechanisms underlying the transduction and analysis of acoustic signals in the auditory periphery. Topics include the acoustics, mechanics, and hydrodynamics of sound transmission; the biophysical basis for cochlear amplification; the production of otoacoustic emissions; the physiology of hair-cell transduction and synaptic transmission; efferent feedback control; the analysis and coding of simple and complex sounds by the inner ear; and the physiological bases for hearing disorders. Based primarily on reading and discussions of original research literature. 
            J. J. Guinan, J. J. Rosowski, C. A. Shera
             
            ————————————————————
            HST.730 Molecular Biology of the Auditory System 
            Prereq: Biology (GIR) 
            Units: 3-0-9 
            Lecture: T EVE (4.30-7.30 PM) (EPL LIB) 
             
            Focuses on molecular approaches to cochlear development and function, based on readings and discussion of research literature. Lectures by course director and local experts in the field. Includes discussion of gene expression, cell fate determination, deafness mutations, stem cells and regeneration of the cochlea. 
            A. Edge
             
            ————————————————————
            HST.973/15.124 Evaluating a Biomedical Business Concept 
            Prereq: None 
            Units: 3-0-6 
            Lecture: W2.30-5.30 (E25-119) 
             
            Involves critical analysis of new biomedical business ideas. Inventors or principals of early stage companies present their ideas and provide background material including scientific papers and patents. Student teams interact with the companies, potential customers, other stakeholders and experts to develop a series of analyses concerning the critical issues. Company and student presentations supplemented by topic-specific lectures and presentations by biomedical entrepreneurs. Enrollment limited. 
            R. J. Cohen
             
            ————————————————————
            HST.978/15.367 Healthcare Ventures 
            Prereq: 15.910; 15.390 or 10.391 or 10.579 
            Units: 3-0-9 
            Lecture: T EVE (5-8 PM) (E51-315) 
             
            Focuses on entrepreneurship, with emphasis on startups bridging digital health and high-tech. Explores US and global macro trends and case studies. Features lectures by leading healthcare entrepreneurs and venture investors, and provides practical experience in networking through team projects. Evaluation based on team participation and assignments, including two team presentations. Video conference facilities provided to facilitate remote participation by Executive MBA and traveling students. Enrollment by application only. Enrollment by application only 
            M. Gray, Z. Chu
             
            ————————————————————
            HST.S52/2.75/6.525 Medical Device Design 
            Prereq: 2.72, 6.071, 6.115, or permission of instructor 
            Units: 3-0-9 
            Lecture: TR2.30-4 (3-442) 
             
            Application of mechanical and electrical engineering fundamentals to the design of medical devices that address clinical needs. Throughout the term, students work in small teams on a major project to translate a clinical challenge into a proof-of-concept prototype device. Students conduct user analysis, develop design specifications, and follow a structured process to cultivate creative designs and apply analytical techniques to optimize them. They deepen their understanding of art and intellectual property by researching prior representations. Develops practical skills in prototyping and testing as well as project management. Includes lectures, problem sets and exams that focus on design fundamentals. Instruction and practice in written and oral communication provided. Students taking graduate version complete additional assignments. Enrollment limited. 
            A. H. Slocum, C. G. Sodini
             
            ————————————————————
            2.S972 Developing Technologies for Music and Health
            Special seminar offered jointly with Berklee College of Music
            Units: 2-0-4
            Lecture: Fridays, 1pm to 3pm, 
            Please indicate your interest by completing our brief survey here: bit.ly/2s972
             
            Students will design and prototype devices that explore music's effects on health and brain functions (sleep, anxiety, athletic performance, and learning). Seminar will include literature review and presentation of current scientific evidence to support use of music to regulate health, plus research on technology for measuring health performance. Students will design a study to test hypotheses related to benefits of music, perform data-analysis of results from group research study, and present findings. Teams will develop and prototype product concepts. Seminar will include numerous special guest lectures. Limited enrollment, by permission of instructor. 
            Ken Zolot, in collaboration with Berklee's Institute for Creative Entrepreneurship, Berklee's Music Therapy Department, and The Sync Project.
             
            ————————————————————
            7.85 The Hallmarks of Cancer (New) 
            (Subject meets with 7.45) 
            Prereq: 7.06 or permission of instructor 
            Units: 4-0-8 
            Lecture: TR11-12.30 (E25-111) 
             
            Provides a comprehensive introduction to the fundamentals of cancer biology and cancer treatment. Topics include cancer genetics, genomics, and epigenetics; familial cancer syndromes; signal transduction, cell cycle control, and apoptosis; cancer metabolism; stem cells and cancer; metastasis; cancer immunology and immunotherapy; conventional and molecularly-targeted therapies; and early detection and prevention. Students taking graduate version complete additional assignments. 
            T. Jacks, M. Vander Heiden
             
            ————————————————————
            7.87 Protein Folding and Misfolding in Biology (New) 
            Prereq: 7.51 and 7.52; or permission of instructor 
            Units: 3-0-6 
            Credit cannot also be received for 7.88 
             
            Covers protein folding, misfolding, aggregation, and amyloid formation in the context of biological systems. Addresses topics such as chaperone structure and function, biofilm formation by bacteria, protein-folding diseases (including but not limited to Alzheimer's, Parkinson's, and Huntington's diseases), the process of therapeutics discovery for drugs and biologics. Features guest lectures and Skype discussions with international leaders in the field. Students present papers covering mutually agreed-upon topics of interest. 
            S. Lindquist
             
            ————————————————————
            10.807[J] Innovation Teams 
            (Same subject as 15.371[J])
            Prereq: 15.911 or permission of instructor
            Units: 4-4-4
            Fridays in 32-155. Lecture: W4.30-7, F9-11.30 (32-124)
             
            Students work in teams to develop commercialization strategies for innovative research projects generated in MIT laboratories. Projects cover critical aspects of commercialization, from selecting the target application and market for the technology to developing an intellectual property strategy and performing a competitive analysis. Instruction provided in communication and teamwork skills, as well as analysis of the challenges and benefits of technology transfer. Includes lectures, guest speakers, and extensive team coaching. Designed primarily for students in engineering, science, and management. Applications, resumes, and a brief statement of interest are required prior to registration.
            F. Murray, L. Perez-Breva, N. Afeyan
             
            ————————————————————
            15.378 Building an Entrepreneurial Venture: Advanced Tools and Techniques
            (Subject meets with 15.3781)
            Prereq: Permission of instructor
            Units: 3-1-8
            Lecture: M EVE (6-9 PM) (E40-160)
             
            Project-based class in which students use entrepreneurial techniques to build innovation-driven ventures in a time-compressed but robust setting. Applies fundamental concepts in greater depth and introduces tools and techniques. Students apply these concepts to specific venture-development projects. Designed to help students who want to prototype their potential new venture. Includes designing, developing, and testing the underlying product/service for the new venture. Students taking graduate version complete additional assignments. Application required; consult instructor.
            B. Aulet, J. Baum, E. Chen
             
            ————————————————————
            MAS.S62 - Engineering Health: Understanding and Designing Affordable Health Diagnostics
            Friday 1-4PM, first class Sept 11, E15-341
             
            Design and build novel health diagnostics and sensors while learning the fundamentals of rapid prototyping, applied optics, signals processing, imaging and other advanced sensing modalities. Students work in teams with a physician and technical mentor to design and construct a cutting edge health diagnostic or device. Exceptional projects will be invited to participate in an optional workshop in India to further develop their device.
             
            Example projects include spectroscopic sensing of ear infection, an automated stethoscope, non-contact blood pressure sensors, ultra wide angle endoscopy, and wound perfusion monitoring.  Structured labs will build engineering and design skills, lectures will introduce considerations for medical design and new prototyping techniques. Grading is based on labs, problem sets, and the semester project, all detailed below. Prior guest speakers have included leading doctors and researchers from the Broad Institute, Harvard, MGH, Partner's in Health, and MIT. Register now as spaces are limited.
            Anshuman Das, Pratik Shah
             
             
             
            HEALTH INFORMATION TECHNOLOGY INNOVATION CLASS
             
            BMI 741: Health Information Technology Innovation: From Ideation to Implementation

            Thursdays, 2-5pm in Countway Library, Room 403, from 9/10-12/10.
             
            Dr. Adam Landman, CMIO of Brigham and Women’s Hospital, and Dr. Gabriel Brat, Acute Care Surgery, BWH  are teaching a course on innovation in the digital health space at Harvard Medical School.  Students enrolled in the course have a background in medicine, public health, and clinical informatics.
             
            We’re advertising to anyone interested in digital health ideation and implementation and willing to be involved for the entire semester. Auditing students are welcome. Participants will help develop a novel health IT solution and learn from a fascinating group  of speakers and panelists.
             
            Feel free to email Dr. Gabriel Brat (Gbrat@partners.org) if you’re interested in the class and want more information

            Course Description:
            As the US healthcare system moves from a fee-for-service to value-based reimbursement system and seeks to deliver higher quality care more efficiently, there is increased need and opportunity for innovation.  Clinical Informatics analyzes, designs, implements, and evaluates information and communication systems to enhance health outcomes, to improve patient care, and to enable healthcare transformation.  This class applies health information technology (HIT) and digital health to solve health care problems, teaching the skills to identify health care needs and pain points, design technology-based solutions (new solution, optimize existing system, or purchase vendor solution), and lead successful implementations.  Course activities will include lectures, panel discussions, and laboratory sessions.  Expert speakers from hospitals, technology vendors, and start-ups will present real-world examples and share lessons learned.  Course participants will complete a longitudinal group project proposing an HIT innovation project; this project may serve as the basis for start-ups, fellowship projects, and research theses.
             
             
            HMS COURSE - MICRO 214
             
            Microbiology 214. Mechanisms of Bacterial Pathogenesis and Host Immune Response  
             
            Tuesdays and Thursdays (10am to 12noon) NRB 1031
            4 credits
             
            This course uses classic and contemporary scientific literature to explore the molecular mechanisms of bacterial pathogenesis and the host response to infection. Through lectures and critical discussions of research methods, results, and interpretations we explore topics including bacterial entry and survival within host cells, the resulting host signaling cascades, innate and adaptive immune responses and the dueling development of antibiotics and antibiotic resistance. The course is designed to complement Microbiology 201.
            Marcia Goldberg, Michael Starnbach, Jonathan Kagan and Darren Higgins
             
            Please contact Brad Coleman (bradley_coleman@hms.harvard.edu), the Curriculum Fellow, with any questions. 
             
             
            HARVARD CATALYST’S MEDICAL DEVICE DEVELOPMENT COURSE
             
            We are now accepting applications for Harvard Catalyst’s Medical Device Development course. This two-day course will provide an introduction to medical device innovation, development, and translation. We appreciate all of your efforts to promote this course to your academic and professional community.
             
            Medical Device Development
            • October 29-30, 2015
            • Sheraton Commander Hotel, Cambridge, MA
            • Apply by September 18, 2015!
            This course is tuition-free for Harvard-affiliated institutions.  
             
            For more information and a detailed description of Medical Device Development, please visit http://catalyst.harvard.edu/services/mdd/
             
            Contact us at med_devices@catalyst.harvard.edu with any questions.
             
            Joanna Chang, Education Program Developer, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
            Phone: 617-432-7113, Fax: 617-432-1560
             
            Casey Falla, Education Program Coordinator, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
            Phone: 617-432-7812, Fax: 617-432-1560
             
             
             
            CALLING FOR LIFE SCIENCES ENTREPRENEURS
             
            Do you have an idea you’d like to commercialize? Would you like to use Boston’s top scientific minds to help you build a business plan, get feedback from leading entrepreneurs & venture capitalists, and take the next step towards commercializing your biomedical brainchild?
             
            You are invited to submit a biomedical idea/invention for use in the 2015 Healthcare Innovation and Commercialization course. Submission will be reviewed based on commercialization potential, originality, and clinical relevance.
             
            PI’s, postdocs, and students are all encouraged to submit their inventions, which will be protected by NDA agreements from course participants.
             
            Please email your idea as a 1-page pdf document to harvardhic2015@gmail.com.

            Submitted ideas should include the following: 
            1) A brief description of yourself and your motivation to submit your idea
            2) Brief background on the problem you're trying to solve
            3) Description of your proposed solution
             
            Please visit http://www.harvardhic2015.com/curriculum.html for more information. 
            We look forward to hearing about your innovative ideas!
             
            HIC Team 2015
             
             
             

             


            Conferences, Lectures & Seminars

             

              STARTUP IN AMERICA: GUIDANCE ON FOREIGN ENTREPRENEURSHIP IN THE U.S. 

              International students at MIT (more than 40 percent of the graduate student population) face unique challenges in founding companies in the U.S. after graduation. On September 25, a panel of alumni entrepreneurs and experts in this field will share experiences and insight on navigating this complex process. Join the MIT Alumni Association and the Graduate Student Council for this panel discussion on legal options for international entrepreneurs, followed by a networking reception. Register here today!

              • Friday, September 25, 2015
              • Panel, 6-7pm
              • Kirsch Auditorium, Stata Center (32-123)
              • Reception, 7-8pm
              • La Sala de Puerto Rico, Stratton Student Center (W20-2nd floor)
              Alumni & Friends of MIT: $10
              MIT Students: free
               
              Panelists: Bernat Olle SM ’05, MBA ’07, PhD ’07, Perihan Abouzeid MBA ’15, Vince Lau, Catherine Fazio JD ’93, MBA ’14
               
              This event is brought to you by the Graduate Student Council Legislative Action Subcommittee, in collaboration with the MIT Alumni Leadership Conference.

               

              MIT MEDIA LAB BREATHE HACKATHON WEEKEND

              Do you breathe?  Do you think everyone should have the opportunity to take a full breath?
               
              Join us for the inaugural event of the global BREATHE Initiative, starting right here at the Media Lab!
               
              The BREATHE Hackathon Weekend is a multi-national event, with three hackathons happening simultaneously in three continents.  It will be big, it will be bold, and you should be a part of it!
               
              PRIZES!
              1st prize -- $3000
              2nd prize -- $2000
              3rd prize -- $1000
              Plus two more $500 awards for Patients' Choice and Team Favorite!
               
              FREE FOOD!  FREE T-SHIRT!  
               
              Our three main innovation areas are Asthma, Apnea, and COPD, but improving all aspects of respiratory wellbeing are encouraged.  We need engineers, app/software developers, designers, marketers, health care professionals, industry experts, and anyone who likes to breathe.
               
              Email respiration@media.mit.edu with questions.  See you there!

               

              WOMEN IN BIOTECH SYMPOSIUM

              • Friday, September 18, 2015
              • 1–5pm
              • Radcliffe Institute for Advanced Study, Harvard University
              Why are women underrepresented as leaders in the biotech industry?
               
              It’s a perplexing issue which warrants examination and discussion. Bringing together scientists, industry and venture capital leaders, and academics, this symposium will explore the divide between the large number of women who pursue advanced degrees in related scientific fields and their representation in leadership positions in biotech firms. Speakers will also share new research, experimentation, and promising models that may help industry, universities, government, and private capital improve the current system. Join us to gain a deeper understanding into this situation.
               
              Register online and view the full schedule: www.radcliffe.harvard.edu/event/2015-women-in-biotech-symposium
               
              Speakers:
              • Alison Wood Brooks, assistant professor of business administration, Harvard Business School
              • Victoria A. Budson, executive director, Women and Public Policy Program, Harvard Kennedy School
              • Daniel Carpenter, director of the social sciences program, Radcliffe Institute; Allie S. Freed Professor of Government in the Faculty of Arts and Sciences, Harvard University
              • Ann DeWitt, senior director of investments, Sanofi-Genzyme Bioventures
              • Deborah Dunsire, president and chief executive offer, Forum Pharmaceuticals
              • Robin Ely, Diane Doerge Wilson Professor of Business Administration and senior associate dean for Culture and Community, Harvard Business School
              • Monica C. Higgins, Kathleen McCartney Professor in Education Leadership, Harvard Graduate School of Education
              • Anula Jayasuriya, cofounder, Evolvence India Life Science Fund and India Life Science Fund II; founder, EXXclaim Capital
              • Janet Rich-Edwards, codirector of the science program, Radcliffe Institute; associate professor of medicine at Harvard Medical School; and associate professor in the department of epidemiology at the Harvard T.H. Chan School of Public Health
              • Laurel Smith-Doerr, professor of sociology and director of the Institute for Social Science Research, University of Massachusetts Amherst
              The event is free and open to the public.

               

              CROSS-INSTITUTIONAL TUMOR IMMUNITY RETREAT

              • Monday, November 16, 2015, 8:30am - Tuesday, November 17, 2015, 4:30pm
              • Joseph B. Martin Conference Center, HMS, 77 Avenue Louis Pasteur, Boston, MA 02115
              • Register at: tumorimmunity.org
              Attendance at the retreat is limited and registration will be made on a first-come first-serve basis.
               
              The event will bring together immunologists, cancer biologists, oncologists, computational biologists, and technologists from HMS and its hospitals, MIT, and the Broad Institute.
               
              The retreat will provide a forum to present the some of the work related to tumor immunity in our research community, and identify opportunities for collaborative research initiatives. 
               
              Program information can be found here.

              Questions?

               

              WINFOCUS CONFERENCE

              11th WINFOCUS World Congress on Ultrasound in Emergency and Critical Care Conference

              • October 22-2015
              • The Joseph B. Martin Conference Center at Harvard Medical School (77 Avenue Louis Pasteur, Boston, MA)
              World Interactive Network Focused On Critical Ultrasound (WINFOCUS) is a multi-specialty, international organization that is now a decade old and helps to promote point of care utilization and education throughout the world.
               
              It will be a great group of super-users, highly interactive and informational and lots of networking opportunities!

              There will be special sessions on medical student curriculum development and a competency assessment discussion panel which might be of interest too.
               
              More information is available at: http://www.winfocus2015.com/.
               
               

              27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM

              Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
              • Thursday, October 1, 2015
              • 2–5:30pm
              • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
              Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
               
              Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
              New York University Langone Medical Center
               
              Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
               
              Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
               

              LEADINGAGE HACKFEST

              • October 30-November 1, 2015 
              • UMass, Boston

              LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

              A Youtube video about the event is available here.   

              Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

               

              PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

              • October 29-30, 2015 
              • Seaport Hotel & World Trade Center, Boston
              This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
               
              The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
               
              Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
               
              For more information and to register, please visit the Symposium website:

               

              MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

              Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

              But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
               
              At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
               
              More information and events from Medtech Boston is available here.
               
               

              MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

              The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

              Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
               
              Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
               
              Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
               
               

              HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

              The HMS JPNM offers a weekly seminar series from September through May/June.
               
              Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
               
              S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
               
              If you would like to be added to the weekly email distribution list for the lectures, please contact:
              Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
               
              Upcoming Seminars:
               
              Stay tuned for Fall 2015 seminar information.

               
              BRAINMAP SEMINARS

              Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
               
              Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
               
              To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
               
              September 15, 2015 - Special Brainmap Seminar - Tuesday, Noon, CNY Building 75, First Floor Conference Room
               
              Falk Eippert, Pain Imaging Neuroscience Group, Nuffield Department of Clinical Neurosciences & FMRIB Centre, John Radcliffe Hospital, University of Oxford
              Imaging pain processing in the human spinal cord 
               
               

              Student Opportunities
               

               
              ONEWORLD ONEMIT RECEPTION
              • Saturday, September 12, 2015
              • 5-7pm 
              • 20 Chimneys Room in the Stratton Student Center

              Come celebrate and experience MIT’s rich cultural and national diversity!

              The Graduate Student Council is hosting the OneWorld OneMIT reception on Saturday, September 12th, 5-7pm, in the 20 Chimneys Room in the Stratton Student Center (84 Massachusetts Ave). Meet both incoming first-year and continuing graduate students from various international as well as racial and ethnic backgrounds. This reception is also an excellent opportunity to connect with graduate student cultural organizations and to learn how you can get involved! There will be a variety of cultural foods and non-alcoholic beverages for all to enjoy. Among the groups expected to participate include: MITaly, Club Argentino, Latinos in Science and Engineering, Black Graduate Students Association, International Students Association, and the Arab Students Organization.
               
              Questions? Please contact gsc-oc@mit.edu.
               
               
              HACKING SCIENCE DEMOS
               
              Communicating Science @ MIT is hosting a 3-hour hackathon to learn about and design science demos with the MIT Museum.  The top five teams will win $100 to develop their ideas, and their designs will be included in science outreach across Massachusetts.
              • Sunday, September 20, 2015
              • 2-5 pm
              • MIT Museum

              Create hands-on Science, Technology, Engineering, Arts, and Math (STEAM) activities and demonstrations for Science on the Street!

              Thanks to the MIT Graduate Student Council, ComMIT and SciStreet are hosting a SciStreet Hackathon to bring together students in teams to create interesting and interactive hands-on activities and demonstrations for public audiences on STEAM topics and themes.

               

              MUSIC ENSEMBLES OPEN TO GRADUATE STUDENTS AT MIT

              There are a number of opportunities for graduate students to participate in music ensembles at MIT:

              • MIT Concert Choir
              • MIT Chamber Chorus
              • MIT Vocal Jazz Ensemble
              • Emerson Program for Private Study
              • MIT Symphony Orchestra
              • MIT Wind Ensemble
              • MIT Chamber Music Society
              • CMS Jazz Combos
              • MIT Festival Jazz Ensemble
              • MIT Gamelan Galak Tika
              • Rambax MIT

              Information about auditioning for these performing groups can be found here.

              Auditions are being held now!

               

              PATEXIA - APPLIED RESEARCH OPPORTUNITIES FOR ENGINEERING STUDENTS

              What we do…

              Patexia is a Los Angeles-based startup that uses crowdsourcing to solve engineering and innovation challenges for some of the largest technology companies and research-oriented organizations in the world. We were recently awarded a contract through the NASA Tournament Lab and we are looking for talented undergraduate and graduate engineering students to join our network as problem solvers and campus ambassadors. 
               
              Applied research opportunities…
               
              Technical Problem Solver
               
              The strength of Patexia’s crowdsourcing model comes from the global community of over 10,000 technical problem solvers and subject matter experts behind it. By joining our professional network as a student member you will have the chance to interface with top companies and research organizations in your field as you develop innovative solutions to real world challenges. Throughout the process you will be collaborating with classmates, professors, and experts from around the globe as you compete against teams from other US and international universities for bragging rights and cash prizes.
               
              Campus Ambassador
               
              As a bridge between industry-driven problems and university-based solutions, we need to work with the very best in order to exceed the expectations of clients such as NASA and Cedars-Sinai Medical Center. The Patexia campus ambassador program is built around well-connected engineering students who can not only help us solve technical problems, but can share their experience with classmates, friends, and professors to help expand our reach. Campus ambassadors will regularly meet and train with the Patexia team and, in addition to compensation for meeting defined recruitment goals, ambassadors will be invited to relevant networking events and be given the opportunity to directly connect with important industry contacts.
               
              How you can get involved...
               
              If you are interested in collaborating with Patexia as a problem solver, campus ambassador, or both please contact us at ambassador@patexia.com. You can also read more about the perks of the ambassador program here on Patexia.
               
               

              HARVARD HEALTH POLICY REVIEW - CALL FOR STUDENT ARTICLES

              HHPR would like to invite you to contribute an article to our Student Contributions section.

              Our Student Contributions articles engage in various topics and issues in health policy from different perspectives. The theme for the Fall 2015 issue is “Precision Medicine.” With the launch of the Precision Medicine Initiative earlier this year by President Obama, the growing recognition of precision medicine by clinicians, patients, researchers, and policy makers reflects the accelerating emergence of this new approach in the field of medicine. We are currently soliciting articles that address the broad implications, opportunities, as well as challenges related to this new initiative. 
               
              The submission deadline for the Spring 2015 issue is September 15, 2015.
               
              Submission guidelines for our publication can be found here.
               
              Please do not hesitate to contact us at hhpr.harvard@gmail.com or hhprstudentcontributions@gmail.com if you have any questions or concerns.

               

              GRADRAT WINE & CHEESE ORIENTATION WELCOME 

              • Friday, September 11, 2015 
              • 5-7pm 
              • Walker Memorial 
               
                          • Come enjoy wine, fruits and cheese!
                          • Free givewaways
                          • Raffles for a free gradrat and 5 $50 discounts
                          • First 200 rings sold will receive a $25 discount

               

              MIT ENGLISH AS A SECOND LANGUAGE VOLUNTEERS NEEDED

              The MIT English as a Second Language Program for Service Employees is looking for volunteers to tutor night shift employees for 1-2 hrs/wk or to serve as substitutes as needed for the Fall semester that runs from September 28 - December 11, 2015.
               
              No experience is required, just a good command of English and an interest in helping individuals whose first language is not English. The goals of the program are to build student’s confidence, to help them become more productive in their jobs, and to perhaps open up further opportunities for advancement.
               
              Tutoring takes place on Tuesdays and Thursdays from 11pm - midnight beginning September 28.

              This is an opportunity to make a real and positive difference..
               
              Please contact esl-admins@mit.edu for details.

               

              MIT VETERANS OUTREACH

              Veteran Students, do you know . . .
               
                 there are two MIT veteran student clubs.
                 that there is a committee dedicated to veterans outreach comprised of faculty, staff and students.
                 that room 50-010 is a space exclusively for veteran students.
                 
              Is this only United States veterans?   No, we serve all students who are veterans.
              Interested in knowing more, please contact Mary Kathryn, extension 4.7824 or mjuskiew@mit.edu.

               

              APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

              Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
              For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

               

              UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

              Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
              nomination.
               
              More information may be found here. 
               
               
              GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

              Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

              Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance MIT graduate
              community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

              Open positions are as follows:

              • Institute Community and Equity Office (one position open for 2015-16)
              Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
              We are accepting applications now and will fill positions on a rolling basis.
              Receive a monthly stipend while you gain experience.  Apply now!
              Questions? Contact Heather Konar (konar@mit.edu)

               

              COMMUNITY SERVICE WEEKLY BULLETIN

              At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
              Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
               
              As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
              efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
               
              Sign up for the weekly Community Service Bulletin of Events and Programs here.
              News and upcoming events are posted on the homepage.

               

               


              Professional Opportunities

               

              POST DOCTORAL FELLOW – KARP LAB / LANGER LAB

              Translational Mucosal Biology & Drug Delivery: Karp Lab / Langer Lab, Boston, MA, USA

              The Karp Lab at Brigham & Women’s Hospital, Harvard Medical School, and the Langer Lab at the Massachusetts Institute of Technology aim to rapidly advance therapeutic solutions for diseases in oral and gastrointestinal mucosa through multidisciplinary approaches. A major focus between our research groups is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients.
               
              This post doctoral fellow will lead a high impact project developing delivery systems for the therapeutic modulation of inflamed mucosa. The successful candidate for this position will be responsible for high-level project design and coordination, in addition to leading a team in experimental execution. The candidate will have strong organizational and communication skills for assisting and collaborating with multidisciplinary groups of technology innovators and engineers, as well as biologists and clinicians, in a dynamic team environment.
               
              Basic Qualifications: Ph.D. and relevant experience in Biology, Bioengineering, Biomedical Engineering, Biochemistry or related degree. Ideally will have ample experience in biochemical techniques, animal handling, and drug delivery vehicles.
               
              The Karp and Langer Labs are dynamic and fast paced environments that thrive on collaboration and ingenuity. We have a diverse, international talent pool, simultaneously working on multiple projects across several disease areas. We are focused on the development of platform technologies supporting a broad range of potential applications in medicine and bioengineering. Our emphasis on translational research enables us to train the next generation of bioengineers and expand the boundaries of this exciting field. With that in mind, we seek members with highly developed interpersonal skills who could contribute to our dynamic lab community.
               
              Interested candidates should email: jmkarp@partners.org and include a cover letter expressing interest and their updated CV with a list of publications.

               

              L.E.K. CONSULTING - PHD & MD RECRUITING

              Company Description
              L.E.K. Consulting is a global management consulting firm that uses deep industry expertise and rigorous analysis to help business leaders achieve practical results with real impact. We are uncompromising in our approach to helping clients consistently make better decisions, deliver improved business performance and create greater shareholder returns. The firm advises and supports global companies that are leaders in their industries — including the largest private and public sector organizations, private equity firms and emerging entrepreneurial businesses. Founded more than 30 years ago, L.E.K. employs more than 1,000 professionals across the Americas, Asia-Pacific and Europe. For more information, go to www.lek.com

               
              Life Sciences Specialist
              L.E.K. Life Sciences Specialists have their Ph.D.s in a science field and are from the top programs at leading universities. Life Sciences Specialists are hired for their expertise in the life sciences field, which has proved invaluable to our clients.
               
              Specific responsibilities include:
              • Gathering primary and secondary data on markets, competitors, and customers through database and Internet searches, market research and other commercial reports, internal client data, and telephone and in-person interviews.
              • Leveraging scientific background and transferring specific knowledge base to the team in order to develop rigorous solutions to client issues.
              • Developing rigorous strategic and financial analysis that will be utilized to determine L.E.K.’s recommendation to the client. Examples include developing a spreadsheet model of market growth and competitor share, developing a valuation model for a company or product using discounted cash flow analysis, testing customer sensitivity to product attributes using adaptive conjoint analysis, or determining probability distributions of acquisition value.
              • Collaborating with project team members to derive trends, conclusions, and recommendations based upon the analysis. A Life Sciences Specialist must transform what he or she has learned into thoughtful insights regarding the client’s strategic direction.
              • Making L.E.K. an enjoyable and rewarding place to work. This includes coaching colleagues and transferring skills, offering constructive advice, and contributing to the social environment of the office.
              Application Requirements
              L.E.K. does not have a rigid checklist of qualities a potential Life Sciences Specialist must possess. Rather, our recruiting experience has shown that outstanding academic achievement, comfort with quantitative analysis, significant professional experiences, notable extracurricular interests, and demonstrated leadership and initiative are excellent preparation for a position within the Life Sciences Specialist Program at L.E.K. Consulting.
               
              Interested applicants should apply online through our website at www.lek.com/careers by September 16, 2015.
               
              L.E.K Consulting is an Equal Opportunity Employer

               

              PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE: OPEN FACULTY POSITIONS

              The School of Engineering, the School of Medicine and the Faculty of Biological Sciences of the Pontificia Universidad Católica de Chile invite applications for two full-time faculty positions in the areas of Biomedical Devices, and Bioinformatics and Computational Biology. The candidate will join other full-time faculty and several part-time appointments in the recently established Institute for Biological and Medical Engineering, dedicated to research and teaching in the areas of Biomedical Imaging and Modelling, Bioinformatics, Systems Biology, Synthetic Biology, Biotechnology, Biomechanics, and Biomaterials.

               

              VL34 - SCIENTIST/SENIOR SCIENTIST IN MOLECULAR BIOLOGY

              VL34, Inc. has an immediate opening for a Scientist/Senior Scientist in molecular biology.  VL34 is an early-stage startup in Cambridge, MA using cutting-edge molecular techniques to help create a novel category of fertility treatment. VL34 was founded by VentureLabs, a unit of Flagship Ventures which has launched over 25 breakthrough companies including Seres Therapeutics, Symbiota, Pronutria, and Moderna Therapeutics. 

              Position Summary
              VL34, Inc. is seeking an exceptional, highly motivated Scientist/Senior Scientist to play a key role in the company’s efforts to build a high-throughput platform to identify molecular targets with applications in the fertility field.  As part of the early team of scientists at VL34, this individual will have wide-ranging responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative group.
               
              Key Qualifications
              Ph.D. in Biology or a related field, with or without postdoc or industry experience 
              Ability to think critically and creatively as part of a fast-paced research team
              Proven hands-on experience with standard molecular biology techniques.
              Especially preferred to have experience with one or more of:
              oCustom library preparation for high-throughput sequencing, single cell or low-input detection
              oProtein engineering, library-based display technologies (yeast, phage), in vitro directed evolution and selection
              Enthusiasm for pushing the frontiers of conventional techniques and comfort in venturing beyond one’s area of expertise
              Great hands in the laboratory and resourceful when starting new techniques from scratch
              Excellent collaboration, communication and interpersonal skills

              Responsibilities
              The successful candidate will work closely with an interdisciplinary team as well as independently to design and execute experiments that support research activities and project goals
              Quickly implement state-of-the-art techniques in new biological models
              Identify modifications to iteratively improve protocols
              Analyze data and help identify molecular targets and follow-up experiments
              Participate in various aspects of the company from establishing collaborations to writing patents to long-term planning
               
              Compensation
              A competitive overall compensation package including: competitive base salary, bonus potential and stock options.
               
              Contact Information
              To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Brian at VL34Jobs@gmail.com.

               

              PURETECH - SENIOR ANALYST

              About PureTech

              PureTech is a science-driven healthcare company, seeking to solve some of today’s toughest health challenges through disruptive approaches. Based in Boston, PureTech has a network of more than 50 experts across multiple disciplines – from entrepreneurs to world-renowned scientists – giving PureTech access to potentially groundbreaking science and technological innovations. PureTech is problem-focused and solution-agnostic, looking beyond traditional disciplines and approaching healthcare problems from different perspectives. Focusing on areas of significant unmet medical need, PureTech evaluates more than 650 ideas per year, prioritizing, testing and selecting what it believes to be the most scientifically and commercially promising concepts to advance.
               
              JOB DESCRIPTION:
              The Senior Analyst will get hands-on experience in entrepreneurship, participate in sourcing and due diligence of technologies and support PureTech's Innovations and team members. This includes:
              Ideation and business planning for next generation technologies
              Conducting strategic analyses & market opportunity assessments
              Undertaking project management & operations of innovations including development of cutting edge technologies
              Participating in analysis and development of intellectual property
              Preparing compelling communication materials, including presentations, for key external stakeholders
               
              QUALIFICATIONS:
              Creativity, smarts & initiative
              PhD in one of the following disciplines from a top tier institution: engineering, physics, computer science, or a life sciences related field
              Business experience is a plus but not required
              Strong presentation and communication skills; candidate should feel comfortable presenting to groups
               
              LOCATION: Boston, Massachusetts
              The position is full time with a competitive salary and benefits. This is a unique opportunity to join one of the most innovative companies in healthcare while getting hands-on startup experience in our Innovations. Please send your resume and cover letter to careers@puretechhealth.com. Be sure to indicate the Senior Analyst Position in the subject of your email.  (E-mail applications sent directly to PureTech staff will not be considered)

               

              POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

              A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

              Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

               

              RESEARCH AND DEVELOPMENT SCIENTIST POSITION

              Aptitude Medical Systems Inc. – Santa Barbara, CA

              Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
               
              Summary
              There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
               
              Why Choose Aptitude
              We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
              We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
               
              Responsibilities
              The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
              • Develop, test, and optimize aptamers, assays and other products
              • Design and execute experiments; process, analyze, and interpret experimental results and data
              • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
              • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
              • Develop original solutions to problems and create new experimental strategies
              • Help set project goals, milestones and continuously track progress and success
              • Prioritize and manage technical tasks for concurrent projects
              • Help and support other project teams or groups when needed
               
              Knowledge, Skills, and Abilities Required
              The four fundamental characteristics that we need on the team are:
              • Willingness to take on any responsibility to enable the team to achieve success
              • A sense of urgency and ability to achieve time-sensitive milestones
              • Persistence to work through challenges and unlock both systematic and creative solutions 
              • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
               
              In addition, we look for the following skills and abilities in top candidates:
              • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
              • Meticulous attention to detail, executing with high accuracy and reproducibility
              • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
              • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
              • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
              • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
               
              Education/Experience Required
              Different combinations of experience and educations will be considered for qualification of this position:
              • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
              • At least four years of work-related experience in a relevant laboratory environment
              • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

               
              PORTAL INSTRUMENTS POSITION AVAILABLE

              Lead Firmware Engineer
               
              About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
               
              Working at Portal Instruments:
              • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
              • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
              • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
              Role and Responsibilities:
              • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
              • Design, build, debug, and optimize the device’s firmware
              • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
              • Integrate with a team of firmware, software, and control engineers.
              • Design, build, debug, and optimize firmware
              • Evaluate system performance by designing, executing, and documenting experimental plans.
              • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
              • Support electrical compliance testing.
              • Support the manufacture and testing of electronic assemblies by providing test procedures
              • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
              Required Skills and Experience:
              • Development of efficient microcontroller firmware in C, preferably ARM.
              • Familiarity with quality system requirements for medical software system development.
              • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
              • Experience with high-bandwidth motion control.
              • Sensor synthesis / sensor fusion.
              • Familiarity with electronic hardware design.
              • Automated integration testing of firmware.
              Qualifications:
              • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
              • 5+ years of experience in commercial development and/or validation.
              • Experience with medical products development and FDA or related product approvals a plus.
              • Outstanding software engineering and design skills.
              • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
              • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
              • Ability to work independently in a start-up environment.
              Salary commensurate with experience; potential equity participation.
               
              To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
               

              10X GENOMICS - POSITIONS AVAILABLE

              10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

              Applications Scientist: Computational Biology
              10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
               
              Computational Biologist: Algorithm Development
              10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
               
              Computer Scientist: Algorithm Development
              Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
               
              We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

              Data Scientist
              10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
               
              For more information about the company and to see the job listings, visit: 10xgenomics.com/company

              To apply for a position please contact jobs@10xgenomics.com

               

              POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

              Graduate Research Assistant: Contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG, setg.mit.edu), has the potential to provide the first direct evidence for life on Mars and on icy moons, as well as enable diverse environmental and clinical applications. Opportunity to 1) develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches, to 2) design, develop, and validate the instrument in the lab, and in the field at terrestrial analogs of Mars or other extreme environments. Responsibilities also include communicating results to the scientific community through publications and presentations.
               
              This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. You will work closely with the Science PI, Christopher Carr (carrlab.org), in association with the project PI Maria Zuber at MIT, the MGH Institutional PI Gary Ruvkun, and other academic and industrial partners.
               
              Job Requirements
              REQUIRED: Undergraduate degree in highly relevant field; strong analytical and problem solving skills. You must be highly motivated, technically excellent, able to work independently and contribute to an interdisciplinary team, and have excellent communication and interpersonal skills. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills highly valued.
               
              How to Apply
              Please send a CV and cover letter with the name and email of three references to chrisc@mit.edu with “SETG Research Assistant Application” in the subject line.

               

              RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

              Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu.

              Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

               

              FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

              Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

              The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

              Responsibilities:

              1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
              2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
              3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
              Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
               
              Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
               
              Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
               
              Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
               
              Availability: Spring 2015 graduates and other recent graduates.
               
              Citizenship: Must be a United States citizen to be eligible for the position.  
               
              Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
               
              Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
               
               

              ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

              Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

              We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

              To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

               

              POSTDOCTORAL FELLOW POSITION - JAIN LAB

              Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
               
              Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
               
              Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
               
               

              IMMUNEERING - POSITIONS AVAILABLE

              Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
               
              This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
               
              Pathway Biology
              Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
               
              Neurodegeneration and CNS Diseases
              Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
               
              Oncology
              Expertise in disease biology and data analysis for cancer research.
               
              Computational Biology
              Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
               
              Next Generation Sequencing (NGS)
              Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
               
              Machine Learning/Statistics (with Biological Applications)
              Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
               
              Responsibilities
              • Develop innovative algorithms and methods for analyzing data to identify biological insights
              • Interpret data from a biological and clinical perspective
              • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
              • Collaborate with colleagues to solve complex computational research problems
              • Present scientific material (written and oral) to diverse audiences
              Minimum Qualifications
              • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
              • Demonstrated experience developing novel algorithms to address complex scientific problems
              • Proven ability to work independently as well as contribute to larger initiatives
              • Effective English communication skills (both written and oral)
              • Proficient in at least one of R, Python, MATLAB, or a similar language.
              • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
              • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
              Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
              • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
              • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
              • Proficient in R
              • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
              For more information, please visit www.immuneering.com
               
              If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

               

              IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

              For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

              Visit IIE online at www.iie.org.
              Please contact the programs directly for additional information or with any questions you may have.
               
              A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

               
               

              Career Programs

               

              GECD FALL CAREER FAIR PREP EVENTS

              MIT Global Education & Career Development (GECD) Career Services offers a number of special events, panels, workshops and extended drop-in hours to help you prepare for the Fall Career Fair on Friday, September 25, 2015.

              Opportunities to prepare for the Fall Career Fair can be found here.

               

              PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

              The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
              Dates for the remainder of the 201 Series are listed below:
              • September 22, 2015: Career Paths in Big DataRegister here.
              • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
              • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
               
              MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
               
              Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
               
              Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
               
              Web Presentations 
              We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
               
              MD Fellowship 
              We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices.   
              Please visit our MD Fellow page to learn more about the program, eligibility and to apply by July 20 for summer 2016 start dates.
               
              Diversity & Inclusion at McKinsey 
              At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
               
                        

              GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

              For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

              The GECD Event calendar can be found here. 
               
               

              GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

              Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
               
               

              MIT CAREERBRIDGE

              There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

               

              Follow HST on Twitter Follow mit_hst on Twitter

               

               


              MEMP - Thesis Defense - Nathan S. Haseley

              $
              0
              0

              Tuesday, September 29, 2015 – 2:00 PM
              MIT, E25-401

              A Single Cell Perspective on Infection

              The clinical course of infection is ultimately determined by a series of cellular interactions between invading pathogens and host immune cells. It has long been understood that these interactions, even when they occur in tissue culture models, give rise to a wide variety of different outcomes, some beneficial to the host, others to the pathogen. These cellular interactions, however, are typically studied at a bulk level; masking this cell-to-cell variation, losing important information about the full range of possible host-pathogen interactions, and leaving the mechanistic basis for these different outcomes largely unexplored. Here, we present a system that combines single-cell RNA sequencing with fluorescent markers of infection outcome to directly correlate host transcription signatures with infection outcome at the single cell level. Applying this system to the well-characterized model of Salmonella enterica infection of mouse macrophages, we found: 1) Unique transcription signatures associated with bacterial exposure and bacterial infection,2) Sustained high levels of heterogeneity in immune pathways in infected macrophages, and3) A novel subpopulation of macrophages characterized by high expression of the Type I Interferon response after infection. Upon further investigation we found that this heterogeneity in the host Type I Interferon response was the result of heterogeneity in the population of infecting bacteria, namely in the extent of PhoPQ-mediated LPS modifications. This work highlights the importance of heterogeneity as a characteristic of bacterial populations that can influence the host immune response. It also demonstrates benefits of examining infection with single-cell resolution. 


              Thesis Supervisor:
              Deborah T. Hung, MD,PhD
              Title: Associate Professor of Microbiology and Immunology, HMS, MGH

              Thesis Committee Chair:
              Lee Gehrke, PhD
              Title: Hermann von Helmholtz Professor of Health Sciences and Technology, MIT; Professor of Microbiology and Immunobiology, HMS

              Thesis Reader:
              James J. Collins, PhD
              Title: Termeer Professor of Bioengineering, Department of Biological Engineering; Professor of Medical Engineering & Science, IMES, MIT

              Date and Time: 
              Tuesday, September 22, 2015 - 2:00pm to 4:00pm
              Location: 

              MIT, E25-401

              This week in HST - September 18, 2015 - Volume 17, Number 3

              $
              0
              0

              HST Community Notices
               

               

              Course Information &
              Academic Resources

              Conferences, Lectures & Seminars
               

              Student Opportunities
               

              Professional Opportunities
               

              Career Programs
               


              HST Community Notices

               

              HST FACULTY POSTER SESSION

              Students and faculty are warmly invited to participate in HST's annual Faculty Poster Session--designed to inform MD and PhD students about research opportunities and to allow faculty to recruit new students to their labs.  
               
              This year’s session will take place:
              • Thursday, September 24, 2015
              • 5-7pm 
              • Harvard Medical School, TMEC Atrium
                Refreshments will be served.
              Posters may take any form in a 4' by 4' format, ranging from an overview of an entire research portfolio to sample results of a recent research project.  
               
              Faculty and students may register a poster at https://hst.mit.edu/go/poster-session.

              If you have any questions, please write to hst-postersession@mit.edu.

               

              HST MEMP ALUMNI PROFILES

              Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
               

              HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

              Reality is merely an illusion, albeit a very persistent one.

                             --ALBERT EINSTEIN

              Give yours a quick check with hst-refs@mit.edu

              The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
               
              Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
               
               

              Course Information & Academic Resources

               
              AERO/ASTRO GUEST SPEAKER
               
              16.400/16.453 Human Systems Engineering - Department of Aeronautics and Astronautics Seminar
               
              “Current Aerospace Medicine and Human Factors Research at the FAA” and “Aerospace Medicine Implications of Exponential Medical Technologies”
              • Thursday, October 8, 2015
              • 9:30-11am
              • 1-190
              Special Guest Speaker: Dr. Melchor Antunano, Director Civil Aerospace Medical Institute at the FAA
               
              Abstracts:
               
              “Current Aerospace Medicine and Human Factors Research at the FAA" 
              CAMI scientists employ sophisticated equipment and facilities to focus on the bioaeronautical aspects of safety and security, including forensic toxicology, toxicogenomics, biochemistry, accident research, passenger and crew protection, survival research, environmental physiology, and vision research. There are three main activities in the Aerospace Medical Research Program: 1) investigation of the injury and death patterns in civilian flight accidents along with meticulous analysis to determine cause(s) and prevention strategies; 2) development of recommendations for protective equipment and procedures; and 3) evaluation of options, on behalf of FAA regulatory and medical certification staff charged with the proposal of safety and health regulations addressing all aircraft cabin occupants. This research program identifies human tolerances, capabilities and failure modes (physiological, psychological, and performance) both in uneventful flights, and during civilian inflight incidents and accidents.  The research results enable the FAA to utilize new and evaluate existing bioaeronautical guide­lines, standards, and models for aircraft cabin equipment, procedures, and environments.  CAMI scientists also study the skills, abilities, behavior, and performance of personnel involved in aerospace operations. Researchers look for ways to optimize human performance, efficiency and safety, through the introduction of new work station/cockpit displays and controls, and the effective selection and training of personnel operating in highly complex technological environments.  CAMI’s Aerospace Human Factors Research Division leads an integrated program of field and laboratory performance research in organizational and human factors aspects of aviation work environments. Research includes, but is not limited to, human performance under various conditions of impairment, human error analysis and remediation, training analysis and career enhancement, impact of advanced automation systems on personnel requirements and performance, human factors evaluations of performance changes associated with advanced multifunction displays and controls in general aviation and air traffic control, and the psycho-physiological aspects of workload on job proficiency and safety in aviation related human-machine systems.
               
              “Aerospace Medicine Implications of Exponential Medical Technologies"
              Increasing capabilities of digital electronic devices such as the number of transistors on integrated circuits doubling approximately every two years (Moore’s Law), decreased RAM cost, increased RAM size, decreased average microprocessor cost, increased microprocessor clock speed, and increased computing processing power, have had a significant impact on accelerated scientific breakthroughs in medical discoveries and technologies, including neuro-technologies, bio-engineering, virtual medical imaging, regenerative medicine, stem cells therapies, cloning, biomedical devices, micro-electro-mechanical systems (MEMS), genomics and gene therapies, nano-medicine, medical robotics, engineered replacement organs, networked health care, etc.  The implementation of new advanced medical technologies are rapidly changing the scope and complexity of Aerospace Medicine and its impact on safety in aviation and space operations, including: 1) Clinical aerospace medicine aspects such as health monitoring, prevention, screening, diagnosis, treatment and rehabilitation of aerospace personnel and passengers, 2) Aeromedical implications for emergency and elective transportation of patients by air, 3) Medical certification/licensing implications (fitness for flight) for aerospace personnel, 4) Operational roles and responsibilities of aerospace medical personnel, 5) Aerospace human factors considerations, 6) Human-machines-environment interactions, 7) Post aerospace accident/incident investigation factors and analytical tools, etc.
               
               
               
              HARVARD CATALYST’S MEDICAL DEVICE DEVELOPMENT COURSE
               
              We are now accepting applications for Harvard Catalyst’s Medical Device Development course. This two-day course will provide an introduction to medical device innovation, development, and translation. We appreciate all of your efforts to promote this course to your academic and professional community.
               
              Medical Device Development
              • October 29-30, 2015
              • Sheraton Commander Hotel, Cambridge, MA
              • Apply by September 18, 2015!
              This course is tuition-free for Harvard-affiliated institutions.  
               
              For more information and a detailed description of Medical Device Development, please visit http://catalyst.harvard.edu/services/mdd/
               
              Contact us at med_devices@catalyst.harvard.edu with any questions.
               
              Joanna Chang, Education Program Developer, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
              Phone: 617-432-7113, Fax: 617-432-1560
               
              Casey Falla, Education Program Coordinator, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
              Phone: 617-432-7812, Fax: 617-432-1560
               
               
               
              CALLING FOR LIFE SCIENCES ENTREPRENEURS
               
              Do you have an idea you’d like to commercialize? Would you like to use Boston’s top scientific minds to help you build a business plan, get feedback from leading entrepreneurs & venture capitalists, and take the next step towards commercializing your biomedical brainchild?
               
              You are invited to submit a biomedical idea/invention for use in the 2015 Healthcare Innovation and Commercialization course. Submission will be reviewed based on commercialization potential, originality, and clinical relevance.
               
              PI’s, postdocs, and students are all encouraged to submit their inventions, which will be protected by NDA agreements from course participants.
               
              Please email your idea as a 1-page pdf document to harvardhic2015@gmail.com.

              Submitted ideas should include the following: 
              1) A brief description of yourself and your motivation to submit your idea
              2) Brief background on the problem you're trying to solve
              3) Description of your proposed solution
               
              Please visit http://www.harvardhic2015.com/curriculum.html for more information. 
              We look forward to hearing about your innovative ideas!
               
              HIC Team 2015
               
               
               

               


              Conferences, Lectures & Seminars

               

                STARTUP IN AMERICA: GUIDANCE ON FOREIGN ENTREPRENEURSHIP IN THE U.S. 

                International students at MIT (more than 40 percent of the graduate student population) face unique challenges in founding companies in the U.S. after graduation. On September 25, a panel of alumni entrepreneurs and experts in this field will share experiences and insight on navigating this complex process. Join the MIT Alumni Association and the Graduate Student Council for this panel discussion on legal options for international entrepreneurs, followed by a networking reception. Register here today!

                • Friday, September 25, 2015
                • Panel, 6-7pm
                • Kirsch Auditorium, Stata Center (32-123)
                • Reception, 7-8pm
                • La Sala de Puerto Rico, Stratton Student Center (W20-2nd floor)
                Alumni & Friends of MIT: $10
                MIT Students: free
                 
                Panelists: Bernat Olle SM ’05, MBA ’07, PhD ’07, Perihan Abouzeid MBA ’15, Vince Lau, Catherine Fazio JD ’93, MBA ’14
                 
                This event is brought to you by the Graduate Student Council Legislative Action Subcommittee, in collaboration with the MIT Alumni Leadership Conference.

                 

                MIT MEDIA LAB BREATHE HACKATHON WEEKEND

                Do you breathe?  Do you think everyone should have the opportunity to take a full breath?
                 
                Join us for the inaugural event of the global BREATHE Initiative, starting right here at the Media Lab!
                 
                The BREATHE Hackathon Weekend is a multi-national event, with three hackathons happening simultaneously in three continents.  It will be big, it will be bold, and you should be a part of it!
                 
                PRIZES!
                1st prize -- $3000
                2nd prize -- $2000
                3rd prize -- $1000
                Plus two more $500 awards for Patients' Choice and Team Favorite!
                 
                FREE FOOD!  FREE T-SHIRT!  
                 
                Our three main innovation areas are Asthma, Apnea, and COPD, but improving all aspects of respiratory wellbeing are encouraged.  We need engineers, app/software developers, designers, marketers, health care professionals, industry experts, and anyone who likes to breathe.
                 
                Email respiration@media.mit.edu with questions.  See you there!

                 

                CROSS-INSTITUTIONAL TUMOR IMMUNITY RETREAT

                • Monday, November 16, 2015, 8:30am - Tuesday, November 17, 2015, 4:30pm
                • Joseph B. Martin Conference Center, HMS, 77 Avenue Louis Pasteur, Boston, MA 02115
                • Register at: tumorimmunity.org
                Attendance at the retreat is limited and registration will be made on a first-come first-serve basis.
                 
                The event will bring together immunologists, cancer biologists, oncologists, computational biologists, and technologists from HMS and its hospitals, MIT, and the Broad Institute.
                 
                The retreat will provide a forum to present the some of the work related to tumor immunity in our research community, and identify opportunities for collaborative research initiatives. 
                 
                Program information can be found here.

                Questions?

                 

                WINFOCUS CONFERENCE

                11th WINFOCUS World Congress on Ultrasound in Emergency and Critical Care Conference

                • October 22-2015
                • The Joseph B. Martin Conference Center at Harvard Medical School (77 Avenue Louis Pasteur, Boston, MA)
                World Interactive Network Focused On Critical Ultrasound (WINFOCUS) is a multi-specialty, international organization that is now a decade old and helps to promote point of care utilization and education throughout the world.
                 
                It will be a great group of super-users, highly interactive and informational and lots of networking opportunities!

                There will be special sessions on medical student curriculum development and a competency assessment discussion panel which might be of interest too.
                 
                More information is available at: http://www.winfocus2015.com/.
                 
                 

                27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM

                Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
                • Thursday, October 1, 2015
                • 2–5:30pm
                • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
                Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
                 
                Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
                New York University Langone Medical Center
                 
                Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
                 
                Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
                 
                 

                LEADINGAGE HACKFEST

                • October 30-November 1, 2015 
                • UMass, Boston

                LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

                A Youtube video about the event is available here.   

                Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

                 

                PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

                • October 29-30, 2015 
                • Seaport Hotel & World Trade Center, Boston
                This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
                 
                The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
                 
                Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
                 
                For more information and to register, please visit the Symposium website:

                 

                MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

                Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

                But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
                 
                At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
                 
                More information and events from Medtech Boston is available here.
                 
                 

                MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

                The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

                Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
                 
                Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
                 
                Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
                 
                 

                HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

                The HMS JPNM offers a weekly seminar series from September through May/June.
                 
                Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
                 
                S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
                 
                If you would like to be added to the weekly email distribution list for the lectures, please contact:
                Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
                 
                Upcoming Seminars:
                 
                Stay tuned for Fall 2015 seminar information.

                 
                BRAINMAP SEMINARS

                Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
                 
                Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
                 
                To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
                 
                September 23, 2015 
                Francesco S. Pavone, PhD, European Laboratory for Non Linear Spectroscopy - University of Florence, Florence, Italy
                Morpho-functional imaging: connecting a single neuron to whole brain
                 
                 

                Student Opportunities
                 

                 
                GRADUATE RA: NEUROENGINEERING IN TRANSLATIONAL RESEARCH
                 
                A neuroengineering RA position is available in the Poon Lab for translational research that combines engineering control theory and neuroscience approaches in solving clinical problems. Will work with basic neuroscientists and clinicians in several multidisciplinary projects seeking improved treatments of patients who are on mechanical ventilation in the ICU or patients with obstructive sleep apnea (heavy snoring); diagnosis and treatment of patients with a rare neurological disease called Rett syndrome; diagnosis and treatment of patients with chronic obstructive pulmonary disease or heart failure; and others.
                 
                Below is a description of one of the ongoing projects. Details of other projects available upon inquiry.
                 
                An excellent opportunity for talented/motivated students interested in biomedical devices to assist in adapting a newly patented ‘smart’ mechanical ventilator (http://www.google.com/patents/US20090194110) which has been FDA-approved for experimental testing in a clinical study that is underway at MGH. This collaborative project between MIT and MGH is sponsored by the National Institutes of Health and a major biomedical device company (Covidien/Medtronic). Work may lead to a SB / Master’s thesis and possible scientific publications down the road. 
                 
                Requirements:  Familiarity with Matlab programming is essential. Background in biomedical devices, control systems, signal processing, physiology is helpful. We are dealing with real patients who are under critical care in the ICU – strong student commitment is a must!
                 
                Responsibilities:  Adapt an existing computer program written in Labview (a Matlab-based software package) for real-time data acquisition and control of a mechanical ventilator currently interfaced to a patient simulator and port it to new platforms suitable for concurrent testing in an animal study (at MIT) and a clinical study on patients in the ICU (at MGH). Interact with research scientists and clinicians carrying out those studies and provide technical support to facilitate those studies. Refine the program to improve its functionality.
                 
                Contact:  Dr. Chi-Sang Poon at Institute for Medical Engineering & Science, cpoon@mit.edu.
                 
                 
                PARTICIPANTS SOUGHT FOR PROJECT IN TELEMEDICINE/TELEHEALTH
                 
                Term: Fall 2015 with option to continue during Spring 2016
                Department/Lab/Center: IMES
                Faculty Supervisor: Visiting Professor Amar Gupta
                Project Title: Global Health, Telemedicine, and Multi-Pronged Approach
                 
                Project Description:
                Telemedicine/telehealth is poised for double digit growth and widespread adoption within the next decade. The remote delivery of healthcare services, fueled by advances in communication and mobile health technologies, has been shown to provide improved outcomes and quality at a reduced per-capita cost. In the wake of the Affordable Care Act, this shift motivates research into both technical and non-technical aspects of telemedicine from the first stage of the patient/physician connection to the later stages of nationwide telehealth data systems.
                 
                This project provides opportunity for multiple students to be involved to study technical, business, policy, and public health issues.  Previous researchers have published their findings in technical, business, medical, and legal journals.  The focus and scope of the activity can be tailored to the background and interest of the concerned student.
                 
                Specific projects include: (i) integrating and analyzing medical data from heterogeneous systems and formats; (ii) proposing new systems for nationwide telehealth data systems; (iii) identifying technical solutions to current barriers in evolving telemedicine concepts; (iv) assessing telemedicine prototype systems that have been deployed in various parts of the world; and (v) analyzing the effects of divergent and patchwork regulations in various U.S states.
                 
                Contact: Interested applicants should submit a recent resume to Professor Amar Gupta at agupta@mit.edu. Please include the preferred number of hours you would like to devote each week to this activity, and a brief statement of the subset of the 5 potential activities (listed above) that interest you. Students can potentially receive academic credit for this work, or use this work as part or complement to their doctoral or masters research in medical field.
                 
                 
                HACKING SCIENCE DEMOS
                 
                Communicating Science @ MIT is hosting a 3-hour hackathon to learn about and design science demos with the MIT Museum.  The top five teams will win $100 to develop their ideas, and their designs will be included in science outreach across Massachusetts.
                • Sunday, September 20, 2015
                • 2-5 pm
                • MIT Museum

                Create hands-on Science, Technology, Engineering, Arts, and Math (STEAM) activities and demonstrations for Science on the Street!

                Thanks to the MIT Graduate Student Council, ComMIT and SciStreet are hosting a SciStreet Hackathon to bring together students in teams to create interesting and interactive hands-on activities and demonstrations for public audiences on STEAM topics and themes.

                 

                PATEXIA - APPLIED RESEARCH OPPORTUNITIES FOR ENGINEERING STUDENTS

                What we do…

                Patexia is a Los Angeles-based startup that uses crowdsourcing to solve engineering and innovation challenges for some of the largest technology companies and research-oriented organizations in the world. We were recently awarded a contract through the NASA Tournament Lab and we are looking for talented undergraduate and graduate engineering students to join our network as problem solvers and campus ambassadors. 
                 
                Applied research opportunities…
                 
                Technical Problem Solver
                 
                The strength of Patexia’s crowdsourcing model comes from the global community of over 10,000 technical problem solvers and subject matter experts behind it. By joining our professional network as a student member you will have the chance to interface with top companies and research organizations in your field as you develop innovative solutions to real world challenges. Throughout the process you will be collaborating with classmates, professors, and experts from around the globe as you compete against teams from other US and international universities for bragging rights and cash prizes.
                 
                Campus Ambassador
                 
                As a bridge between industry-driven problems and university-based solutions, we need to work with the very best in order to exceed the expectations of clients such as NASA and Cedars-Sinai Medical Center. The Patexia campus ambassador program is built around well-connected engineering students who can not only help us solve technical problems, but can share their experience with classmates, friends, and professors to help expand our reach. Campus ambassadors will regularly meet and train with the Patexia team and, in addition to compensation for meeting defined recruitment goals, ambassadors will be invited to relevant networking events and be given the opportunity to directly connect with important industry contacts.
                 
                How you can get involved...
                 
                If you are interested in collaborating with Patexia as a problem solver, campus ambassador, or both please contact us at ambassador@patexia.com. You can also read more about the perks of the ambassador program here on Patexia.
                 
                 

                MIT ENGLISH AS A SECOND LANGUAGE VOLUNTEERS NEEDED

                The MIT English as a Second Language Program for Service Employees is looking for volunteers to tutor night shift employees for 1-2 hrs/wk or to serve as substitutes as needed for the Fall semester that runs from September 28 - December 11, 2015.
                 
                No experience is required, just a good command of English and an interest in helping individuals whose first language is not English. The goals of the program are to build student’s confidence, to help them become more productive in their jobs, and to perhaps open up further opportunities for advancement.
                 
                Tutoring takes place on Tuesdays and Thursdays from 11pm - midnight beginning September 28.

                This is an opportunity to make a real and positive difference..
                 
                Please contact esl-admins@mit.edu for details.

                 

                APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

                Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
                For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

                 

                UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

                Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
                nomination.
                 
                More information may be found here. 
                 
                 
                GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

                Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

                Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance the MIT graduate
                community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

                Open positions are as follows:

                • Institute Community and Equity Office (one position open for 2015-16)
                Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
                We are accepting applications now and will fill positions on a rolling basis.
                Receive a monthly stipend while you gain experience.  Apply now!
                Questions? Contact Heather Konar (konar@mit.edu)

                 

                COMMUNITY SERVICE WEEKLY BULLETIN

                At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
                Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
                 
                As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
                efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
                 
                Sign up for the weekly Community Service Bulletin of Events and Programs here.
                News and upcoming events are posted on the homepage.

                 

                 


                Professional Opportunities

                 

                MOORE-SLOAN FUNDED POSTDOC POSITION IN DATA AND HEALTH

                A Moore-Sloan funded Post-doctoral opportunity in developing novel computational approaches for disease surveillance is available at the Laboratory of Dr. Rumi Chunara in Computer Science & Engineering, and the College of Global of Public Health at New York University. We are seeking a highly motivated researcher interested in developing and studying new computational methods for using Internet and mobile connected data sources to understand disease in populations worldwide. The postdoctoral fellow will be part of and leverage the vibrant Moore-Sloan Data Science environment at NYU (and Berkeley and UW) which includes numerous faculty and pertinent events.

                Ideal candidates will have a Ph.D. with a strong background in computer science, statistics, bioinformatics, or related field. Preferred requirements for this position include experience designing software applications and/or storing, retrieving, and analyze large datasets. Experience with R, Python, SQL, JavaScript is preferred. Experience in hacking with cloud technologies (e.g., AWS, Hadoop) is a big plus. You must demonstrate an interest or experience in working with biological data such as genomic sequence, syndromic surveillance or physiological data.
                This is an exciting research area and New York City provides great opportunities for networking and support of innovative work. Our group is engaged in many high-profile studies in collaboration with startups and other groups. The selected post-doc will be supported and encouraged to generate high impact publications, gain experience in supervising students and in grant writing if interested. All applicants should send a CV to Rumi Chunara (rumi.chunara@nyu.edu). The position is available immediately.

                 

                POST DOCTORAL FELLOW – KARP LAB / LANGER LAB

                Translational Mucosal Biology & Drug Delivery: Karp Lab / Langer Lab, Boston, MA, USA

                The Karp Lab at Brigham & Women’s Hospital, Harvard Medical School, and the Langer Lab at the Massachusetts Institute of Technology aim to rapidly advance therapeutic solutions for diseases in oral and gastrointestinal mucosa through multidisciplinary approaches. A major focus between our research groups is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients.
                 
                This post doctoral fellow will lead a high impact project developing delivery systems for the therapeutic modulation of inflamed mucosa. The successful candidate for this position will be responsible for high-level project design and coordination, in addition to leading a team in experimental execution. The candidate will have strong organizational and communication skills for assisting and collaborating with multidisciplinary groups of technology innovators and engineers, as well as biologists and clinicians, in a dynamic team environment.
                 
                Basic Qualifications: Ph.D. and relevant experience in Biology, Bioengineering, Biomedical Engineering, Biochemistry or related degree. Ideally will have ample experience in biochemical techniques, animal handling, and drug delivery vehicles.
                 
                The Karp and Langer Labs are dynamic and fast paced environments that thrive on collaboration and ingenuity. We have a diverse, international talent pool, simultaneously working on multiple projects across several disease areas. We are focused on the development of platform technologies supporting a broad range of potential applications in medicine and bioengineering. Our emphasis on translational research enables us to train the next generation of bioengineers and expand the boundaries of this exciting field. With that in mind, we seek members with highly developed interpersonal skills who could contribute to our dynamic lab community.
                 
                Interested candidates should email: jmkarp@partners.org and include a cover letter expressing interest and their updated CV with a list of publications.

                 

                PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE: OPEN FACULTY POSITIONS

                The School of Engineering, the School of Medicine and the Faculty of Biological Sciences of the Pontificia Universidad Católica de Chile invite applications for two full-time faculty positions in the areas of Biomedical Devices, and Bioinformatics and Computational Biology. The candidate will join other full-time faculty and several part-time appointments in the recently established Institute for Biological and Medical Engineering, dedicated to research and teaching in the areas of Biomedical Imaging and Modelling, Bioinformatics, Systems Biology, Synthetic Biology, Biotechnology, Biomechanics, and Biomaterials.

                 

                VL34 - SCIENTIST/SENIOR SCIENTIST IN MOLECULAR BIOLOGY

                VL34, Inc. has an immediate opening for a Scientist/Senior Scientist in molecular biology.  VL34 is an early-stage startup in Cambridge, MA using cutting-edge molecular techniques to help create a novel category of fertility treatment. VL34 was founded by VentureLabs, a unit of Flagship Ventures which has launched over 25 breakthrough companies including Seres Therapeutics, Symbiota, Pronutria, and Moderna Therapeutics. 

                Position Summary
                VL34, Inc. is seeking an exceptional, highly motivated Scientist/Senior Scientist to play a key role in the company’s efforts to build a high-throughput platform to identify molecular targets with applications in the fertility field.  As part of the early team of scientists at VL34, this individual will have wide-ranging responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative group.
                 
                Key Qualifications
                Ph.D. in Biology or a related field, with or without postdoc or industry experience 
                Ability to think critically and creatively as part of a fast-paced research team
                Proven hands-on experience with standard molecular biology techniques.
                Especially preferred to have experience with one or more of:
                oCustom library preparation for high-throughput sequencing, single cell or low-input detection
                oProtein engineering, library-based display technologies (yeast, phage), in vitro directed evolution and selection
                Enthusiasm for pushing the frontiers of conventional techniques and comfort in venturing beyond one’s area of expertise
                Great hands in the laboratory and resourceful when starting new techniques from scratch
                Excellent collaboration, communication and interpersonal skills

                Responsibilities
                The successful candidate will work closely with an interdisciplinary team as well as independently to design and execute experiments that support research activities and project goals
                Quickly implement state-of-the-art techniques in new biological models
                Identify modifications to iteratively improve protocols
                Analyze data and help identify molecular targets and follow-up experiments
                Participate in various aspects of the company from establishing collaborations to writing patents to long-term planning
                 
                Compensation
                A competitive overall compensation package including: competitive base salary, bonus potential and stock options.
                 
                Contact Information
                To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Brian at VL34Jobs@gmail.com.

                 

                PURETECH - SENIOR ANALYST

                About PureTech

                PureTech is a science-driven healthcare company, seeking to solve some of today’s toughest health challenges through disruptive approaches. Based in Boston, PureTech has a network of more than 50 experts across multiple disciplines – from entrepreneurs to world-renowned scientists – giving PureTech access to potentially groundbreaking science and technological innovations. PureTech is problem-focused and solution-agnostic, looking beyond traditional disciplines and approaching healthcare problems from different perspectives. Focusing on areas of significant unmet medical need, PureTech evaluates more than 650 ideas per year, prioritizing, testing and selecting what it believes to be the most scientifically and commercially promising concepts to advance.
                 
                Job Description:
                The Senior Analyst will get hands-on experience in entrepreneurship, participate in sourcing and due diligence of technologies and support PureTech's Innovations and team members. This includes:
                Ideation and business planning for next generation technologies
                Conducting strategic analyses & market opportunity assessments
                Undertaking project management & operations of innovations including development of cutting edge technologies
                Participating in analysis and development of intellectual property
                Preparing compelling communication materials, including presentations, for key external stakeholders
                 
                Qualifications:
                Creativity, smarts & initiative
                PhD in one of the following disciplines from a top tier institution: engineering, physics, computer science, or a life sciences related field
                Business experience is a plus but not required
                Strong presentation and communication skills; candidate should feel comfortable presenting to groups
                 
                Location: Boston, Massachusetts
                The position is full time with a competitive salary and benefits. This is a unique opportunity to join one of the most innovative companies in healthcare while getting hands-on startup experience in our Innovations. Please send your resume and cover letter to careers@puretechhealth.com. Be sure to indicate the Senior Analyst Position in the subject of your email.  (E-mail applications sent directly to PureTech staff will not be considered)

                 

                POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

                A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

                Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

                 

                RESEARCH AND DEVELOPMENT SCIENTIST POSITION

                Aptitude Medical Systems Inc. – Santa Barbara, CA

                Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
                 
                Summary
                There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
                 
                Why Choose Aptitude
                We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
                We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
                 
                Responsibilities
                The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
                • Develop, test, and optimize aptamers, assays and other products
                • Design and execute experiments; process, analyze, and interpret experimental results and data
                • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
                • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
                • Develop original solutions to problems and create new experimental strategies
                • Help set project goals, milestones and continuously track progress and success
                • Prioritize and manage technical tasks for concurrent projects
                • Help and support other project teams or groups when needed
                 
                Knowledge, Skills, and Abilities Required
                The four fundamental characteristics that we need on the team are:
                • Willingness to take on any responsibility to enable the team to achieve success
                • A sense of urgency and ability to achieve time-sensitive milestones
                • Persistence to work through challenges and unlock both systematic and creative solutions 
                • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
                 
                In addition, we look for the following skills and abilities in top candidates:
                • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
                • Meticulous attention to detail, executing with high accuracy and reproducibility
                • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
                • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
                • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
                • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
                 
                Education/Experience Required
                Different combinations of experience and educations will be considered for qualification of this position:
                • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
                • At least four years of work-related experience in a relevant laboratory environment
                • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

                 
                PORTAL INSTRUMENTS POSITION AVAILABLE

                Lead Firmware Engineer
                 
                About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
                 
                Working at Portal Instruments:
                • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
                • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
                • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
                Role and Responsibilities:
                • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
                • Design, build, debug, and optimize the device’s firmware
                • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
                • Integrate with a team of firmware, software, and control engineers.
                • Design, build, debug, and optimize firmware
                • Evaluate system performance by designing, executing, and documenting experimental plans.
                • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
                • Support electrical compliance testing.
                • Support the manufacture and testing of electronic assemblies by providing test procedures
                • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
                Required Skills and Experience:
                • Development of efficient microcontroller firmware in C, preferably ARM.
                • Familiarity with quality system requirements for medical software system development.
                • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
                • Experience with high-bandwidth motion control.
                • Sensor synthesis / sensor fusion.
                • Familiarity with electronic hardware design.
                • Automated integration testing of firmware.
                Qualifications:
                • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
                • 5+ years of experience in commercial development and/or validation.
                • Experience with medical products development and FDA or related product approvals a plus.
                • Outstanding software engineering and design skills.
                • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
                • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
                • Ability to work independently in a start-up environment.
                Salary commensurate with experience; potential equity participation.
                 
                To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
                 

                10X GENOMICS - POSITIONS AVAILABLE

                10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

                Applications Scientist: Computational Biology
                10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
                 
                Computational Biologist: Algorithm Development
                10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
                 
                Computer Scientist: Algorithm Development
                Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
                 
                We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

                Data Scientist
                10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
                 
                For more information about the company and to see the job listings, visit: 10xgenomics.com/company

                To apply for a position please contact jobs@10xgenomics.com

                 

                POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

                Graduate Research Assistant: Contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG, setg.mit.edu), has the potential to provide the first direct evidence for life on Mars and on icy moons, as well as enable diverse environmental and clinical applications. Opportunity to 1) develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches, to 2) design, develop, and validate the instrument in the lab, and in the field at terrestrial analogs of Mars or other extreme environments. Responsibilities also include communicating results to the scientific community through publications and presentations.
                 
                This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. You will work closely with the Science PI, Christopher Carr (carrlab.org), in association with the project PI Maria Zuber at MIT, the MGH Institutional PI Gary Ruvkun, and other academic and industrial partners.
                 
                Job Requirements
                REQUIRED: Undergraduate degree in highly relevant field; strong analytical and problem solving skills. You must be highly motivated, technically excellent, able to work independently and contribute to an interdisciplinary team, and have excellent communication and interpersonal skills. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills highly valued.
                 
                How to Apply
                Please send a CV and cover letter with the name and email of three references to chrisc@mit.edu with “SETG Research Assistant Application” in the subject line.

                 

                RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

                Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu.

                Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

                 

                FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

                Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

                The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

                Responsibilities:

                1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
                2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
                3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
                Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
                 
                Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
                 
                Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
                 
                Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
                 
                Availability: Spring 2015 graduates and other recent graduates.
                 
                Citizenship: Must be a United States citizen to be eligible for the position.  
                 
                Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
                 
                Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
                 
                 

                ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

                Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

                We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

                To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

                 

                POSTDOCTORAL FELLOW POSITION - JAIN LAB

                Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
                 
                Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
                 
                Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
                 
                 

                IMMUNEERING - POSITIONS AVAILABLE

                Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
                 
                This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
                 
                Pathway Biology
                Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
                 
                Neurodegeneration and CNS Diseases
                Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
                 
                Oncology
                Expertise in disease biology and data analysis for cancer research.
                 
                Computational Biology
                Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
                 
                Next Generation Sequencing (NGS)
                Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
                 
                Machine Learning/Statistics (with Biological Applications)
                Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
                 
                Responsibilities
                • Develop innovative algorithms and methods for analyzing data to identify biological insights
                • Interpret data from a biological and clinical perspective
                • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
                • Collaborate with colleagues to solve complex computational research problems
                • Present scientific material (written and oral) to diverse audiences
                Minimum Qualifications
                • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
                • Demonstrated experience developing novel algorithms to address complex scientific problems
                • Proven ability to work independently as well as contribute to larger initiatives
                • Effective English communication skills (both written and oral)
                • Proficient in at least one of R, Python, MATLAB, or a similar language.
                • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
                • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
                Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
                • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
                • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
                • Proficient in R
                • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
                For more information, please visit www.immuneering.com
                 
                If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

                 

                IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

                For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

                Visit IIE online at www.iie.org.
                Please contact the programs directly for additional information or with any questions you may have.
                 
                A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

                 
                 

                Career Programs

                 

                GECD FALL CAREER FAIR PREP EVENTS

                MIT Global Education & Career Development (GECD) Career Services offers a number of special events, panels, workshops and extended drop-in hours to help you prepare for the Fall Career Fair on Friday, September 25, 2015.

                Opportunities to prepare for the Fall Career Fair can be found here.

                 

                PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

                The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
                Dates for the remainder of the 201 Series are listed below:
                • September 22, 2015: Career Paths in Big DataRegister here.
                • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
                • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
                 
                MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
                 
                Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
                 
                Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
                 
                Web Presentations 
                We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
                 
                MD Fellowship 
                We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices. Please visit our MD Fellow page to learn more about the program. Winter Interview Cycle: Early December application deadline with interviews taking place in January-February 2016
                 
                Diversity & Inclusion at McKinsey 
                At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
                 
                          

                GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

                For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

                The GECD Event calendar can be found here. 
                 
                 

                GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

                Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
                 
                 

                MIT CAREERBRIDGE

                There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

                 

                Follow HST on Twitter Follow mit_hst on Twitter

                 

                 

                This week in HST - September 25, 2015 - Volume 17, Number 4

                $
                0
                0

                HST Community Notices
                 

                 

                Course Information &
                Academic Resources

                Conferences, Lectures & Seminars
                 

                Student Opportunities
                 

                Professional Opportunities
                 

                Career Programs
                 


                HST Community Notices

                 

                IMES DISTINGUISHED SPEAKER SERIES

                The IMES Distinguished Speaker Series invites you to attend a lecture by Dr. Sridevi Sarma.
                 
                "On the Therapeutic Mechanisms of Deep Brain Stimulation for Parkinson’s disease: Why High Frequency?" 
                • Thursday, October 15, 2015
                • 4:30pm
                • E25-111
                Sridevi V. Sarma (M’04) received the B.S. degree in electrical engineering from Cornell University, Ithaca NY, in 1994; and an M.S.  and Ph.D. degrees in Electrical Engineering and Computer Science from Massachusetts Institute of Technology in, Cambridge MA, in 1997 and 2006, respectively. She was a Postdoctoral Fellow in the Brain and Cognitive Sciences Department at the Massachusetts Institute of Technology, Cambridge, from 2006-2009.  She is now an assistant professor in the Institute for Computational Medicine, Department of Biomedical Engineering, at Johns Hopkins University, Baltimore MD. Her research interests include modeling, estimation and control of neural systems using electrical stimulation. She is a recipient of the GE faculty for the future scholarship, a National Science Foundation graduate research fellow, a L’Oreal For Women in Science fellow, the Burroughs Wellcome Fund Careers at the Scientific Interface Award, the Krishna Kumar New Investigator Award from the North American Neuromodulation Society, and a recipient of the Presidential Early Career Award for Scientists and Engineers (PECASE). 
                 
                Abstract:
                Deep brain stimulation (DBS) is clinically recognized to treat movement disorders in Parkinson’s disease (PD), but its therapeutic mechanisms remain elusive. One thing is clear though: high frequency periodic DBS (130-180Hz) is therapeutic, while low frequency DBS is not therapeutic and may even worsen symptoms. So, what is so special about high frequency? In this talk, we address this question by discussing our viewpoint supported by recent results from our key studies of the thalamo-cortical-basal ganglia motor network.
                 
                First, thalamic cells play a pivotal role in performing movements by selectively relaying motor-related information back to cortex under the control of modulatory signals from the basal ganglia (BG). Through computational models of thalamic cells, systems theory and analysis, and single unit recordings from primates, we show that (i) there is a set of BG signals ("Proper Relay Set", PRS), under which the thalamic cells can reliably relay the motor commands, and that (ii) the BG signals belong to the PRS in healthy conditions but are outside the PRS under PD conditions.
                 
                Then, we use a detailed computational model of the motor network under PD conditions to study the effects of DBS on the BG signals projecting to the thalamic cells. We show that high frequency periodic DBS steers the BG signals back to the PRS while lower frequency regular DBS and irregular DBS do not. Furthermore, we show that DBS pulses evoke inputs that propagate through the motor circuit both orthodromically (i.e., forward) and antidromically (i.e., backward) and fade away within a few milliseconds, thus having little effects on the BG signals. However, when the latency between consecutive DBS pulses is small (i.e., DBS is high frequency) and constant over time (i.e., DBS is periodic), then orthodromic and antidromic effects overlap in the loop and result in a strong, long-lasting perturbation that ultimately drives the BG signals back to the PRS.
                 
                Taken together, these results provide a holistic view of motor control in healthy and PD conditions, account for the neural mechanisms of therapeutic DBS, and suggest that the merit of DBS critically depends on loop delays in the closed-loop thalamo-cortical-basal ganglia system.
                 
                 

                HST MEMP ALUMNI PROFILES

                Get to know about the path, accomplishments and current activities of selected Medical Engineering and Medical Physics (HST MEMP) alumni at the HST website here.
                 

                HST REFS (RESOURCES FOR EASING FRICTION AND STRESS) INVITE CONTACT

                Reality is merely an illusion, albeit a very persistent one.

                               --ALBERT EINSTEIN

                Give yours a quick check with hst-refs@mit.edu

                The HST REFS want to remind you that they are here for you if you are feeling stressed, frustrated, or simply want to talk to someone. The team is made up of five past and present HST students who are formally trained in mediation services, and can provide confidentiality and function independently of MIT. They are here to be your first point of contact for a range of issues including conflicts within lab or matters of a more personal nature. For more information about them, visit: http://hst.mit.edu/people/students/hst-refs.
                 
                Any of the REFS are available for scheduled meetings at a mutually convenient time and location, so please feel free to email them at hst-refs@mit.edu.
                 
                 

                Course Information & Academic Resources

                 
                IMPLEMENTING INNOVATION AT THE HARVARD I-LAB & I-LAB OFFICE HOURS @ LONGWOOD
                 
                "Implementing Innovation at the Harvard i-lab" session
                • Thursday, October 1, 2015
                • 6-7pm
                • 240 Longwood, Building C, Cannon Room
                • Open to all Harvard students and affiliates
                Please join i-lab Assistant Director, Alice Ly, Ph.D., and a few i-lab Venture Incubation Program teams for a presentation and Q&A on the different activities and resources available to you at the i-lab to start exploring how to get involved, execute on your ideas and take them as far as they can go.
                 
                Speakers: Alice Ly, Ph.D. - Assistant Director, Harvard innovation lab, Alok Tayi, Ph.D. - CEO/Co-founder, TetraScience (i-lab and Y Combinator team), Andrew Le, HMS student - CEO/Co-founder, Buoy (i-lab team)
                 
                i-lab Health & Sciences Office Hours w/ Alice Ly
                Want advice on next steps on how to begin developing/building your idea? Sign up for office hours with Alice Ly, i-lab Assistant Director.
                 
                 
                AERO/ASTRO GUEST SPEAKER
                 
                16.400/16.453 Human Systems Engineering - Department of Aeronautics and Astronautics Seminar
                 
                “Current Aerospace Medicine and Human Factors Research at the FAA” and “Aerospace Medicine Implications of Exponential Medical Technologies”
                • Thursday, October 8, 2015
                • 9:30-11am
                • 1-190
                Special Guest Speaker: Dr. Melchor Antunano, Director Civil Aerospace Medical Institute at the FAA
                 
                Abstracts:
                 
                “Current Aerospace Medicine and Human Factors Research at the FAA" 
                CAMI scientists employ sophisticated equipment and facilities to focus on the bioaeronautical aspects of safety and security, including forensic toxicology, toxicogenomics, biochemistry, accident research, passenger and crew protection, survival research, environmental physiology, and vision research. There are three main activities in the Aerospace Medical Research Program: 1) investigation of the injury and death patterns in civilian flight accidents along with meticulous analysis to determine cause(s) and prevention strategies; 2) development of recommendations for protective equipment and procedures; and 3) evaluation of options, on behalf of FAA regulatory and medical certification staff charged with the proposal of safety and health regulations addressing all aircraft cabin occupants. This research program identifies human tolerances, capabilities and failure modes (physiological, psychological, and performance) both in uneventful flights, and during civilian inflight incidents and accidents.  The research results enable the FAA to utilize new and evaluate existing bioaeronautical guide­lines, standards, and models for aircraft cabin equipment, procedures, and environments.  CAMI scientists also study the skills, abilities, behavior, and performance of personnel involved in aerospace operations. Researchers look for ways to optimize human performance, efficiency and safety, through the introduction of new work station/cockpit displays and controls, and the effective selection and training of personnel operating in highly complex technological environments.  CAMI’s Aerospace Human Factors Research Division leads an integrated program of field and laboratory performance research in organizational and human factors aspects of aviation work environments. Research includes, but is not limited to, human performance under various conditions of impairment, human error analysis and remediation, training analysis and career enhancement, impact of advanced automation systems on personnel requirements and performance, human factors evaluations of performance changes associated with advanced multifunction displays and controls in general aviation and air traffic control, and the psycho-physiological aspects of workload on job proficiency and safety in aviation related human-machine systems.
                 
                “Aerospace Medicine Implications of Exponential Medical Technologies"
                Increasing capabilities of digital electronic devices such as the number of transistors on integrated circuits doubling approximately every two years (Moore’s Law), decreased RAM cost, increased RAM size, decreased average microprocessor cost, increased microprocessor clock speed, and increased computing processing power, have had a significant impact on accelerated scientific breakthroughs in medical discoveries and technologies, including neuro-technologies, bio-engineering, virtual medical imaging, regenerative medicine, stem cells therapies, cloning, biomedical devices, micro-electro-mechanical systems (MEMS), genomics and gene therapies, nano-medicine, medical robotics, engineered replacement organs, networked health care, etc.  The implementation of new advanced medical technologies are rapidly changing the scope and complexity of Aerospace Medicine and its impact on safety in aviation and space operations, including: 1) Clinical aerospace medicine aspects such as health monitoring, prevention, screening, diagnosis, treatment and rehabilitation of aerospace personnel and passengers, 2) Aeromedical implications for emergency and elective transportation of patients by air, 3) Medical certification/licensing implications (fitness for flight) for aerospace personnel, 4) Operational roles and responsibilities of aerospace medical personnel, 5) Aerospace human factors considerations, 6) Human-machines-environment interactions, 7) Post aerospace accident/incident investigation factors and analytical tools, etc.
                 
                 
                 
                HARVARD CATALYST’S MEDICAL DEVICE DEVELOPMENT COURSE
                 
                We are now accepting applications for Harvard Catalyst’s Medical Device Development course. This two-day course will provide an introduction to medical device innovation, development, and translation. We appreciate all of your efforts to promote this course to your academic and professional community.
                 
                Medical Device Development
                • October 29-30, 2015
                • Sheraton Commander Hotel, Cambridge, MA
                • Apply by September 18, 2015!
                This course is tuition-free for Harvard-affiliated institutions.  
                 
                For more information and a detailed description of Medical Device Development, please visit http://catalyst.harvard.edu/services/mdd/
                 
                Contact us at med_devices@catalyst.harvard.edu with any questions.
                 
                Joanna Chang, Education Program Developer, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
                Phone: 617-432-7113, Fax: 617-432-1560
                 
                Casey Falla, Education Program Coordinator, Harvard Catalyst - 107 Avenue Louis Pasteur, Boston, MA 02115
                Phone: 617-432-7812, Fax: 617-432-1560
                 
                 
                 
                 
                 

                 


                Conferences, Lectures & Seminars

                 

                  STARTUP IN AMERICA: GUIDANCE ON FOREIGN ENTREPRENEURSHIP IN THE U.S. 

                  International students at MIT (more than 40 percent of the graduate student population) face unique challenges in founding companies in the U.S. after graduation. On September 25, a panel of alumni entrepreneurs and experts in this field will share experiences and insight on navigating this complex process. Join the MIT Alumni Association and the Graduate Student Council for this panel discussion on legal options for international entrepreneurs, followed by a networking reception. Register here today!

                  • Friday, September 25, 2015
                  • Panel, 6-7pm
                  • Kirsch Auditorium, Stata Center (32-123)
                  • Reception, 7-8pm
                  • La Sala de Puerto Rico, Stratton Student Center (W20-2nd floor)
                  Alumni & Friends of MIT: $10
                  MIT Students: free
                   
                  Panelists: Bernat Olle SM ’05, MBA ’07, PhD ’07, Perihan Abouzeid MBA ’15, Vince Lau, Catherine Fazio JD ’93, MBA ’14
                   
                  This event is brought to you by the Graduate Student Council Legislative Action Subcommittee, in collaboration with the MIT Alumni Leadership Conference.

                   

                  CROSS-INSTITUTIONAL TUMOR IMMUNITY RETREAT

                  • Monday, November 16, 2015, 8:30am - Tuesday, November 17, 2015, 4:30pm
                  • Joseph B. Martin Conference Center, HMS, 77 Avenue Louis Pasteur, Boston, MA 02115
                  • Register at: tumorimmunity.org
                  Attendance at the retreat is limited and registration will be made on a first-come first-serve basis.
                   
                  The event will bring together immunologists, cancer biologists, oncologists, computational biologists, and technologists from HMS and its hospitals, MIT, and the Broad Institute.
                   
                  The retreat will provide a forum to present the some of the work related to tumor immunity in our research community, and identify opportunities for collaborative research initiatives. 
                   
                  Program information can be found here.

                  Questions?

                   

                  WINFOCUS CONFERENCE

                  11th WINFOCUS World Congress on Ultrasound in Emergency and Critical Care Conference

                  • October 22-2015
                  • The Joseph B. Martin Conference Center at Harvard Medical School (77 Avenue Louis Pasteur, Boston, MA)
                  World Interactive Network Focused On Critical Ultrasound (WINFOCUS) is a multi-specialty, international organization that is now a decade old and helps to promote point of care utilization and education throughout the world.
                   
                  It will be a great group of super-users, highly interactive and informational and lots of networking opportunities!

                  There will be special sessions on medical student curriculum development and a competency assessment discussion panel which might be of interest too.
                   
                  More information is available at: http://www.winfocus2015.com/.
                   
                   

                  27TH ANNUAL WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM

                  Vaccines and Therapeutics in the Developing World, Malaria and Beyond 
                  • Thursday, October 1, 2015
                  • 2–5:30pm
                  • Joseph B. Martin Conference Center, New Research Building, HMS, 77 Avenue Louis Pasteur, Boston
                  Congratulations to the 2015 Warren Alpert Foundation Prize recipients:
                   
                  Ruth S. Nussenzweig, Research Professor of Pathology, Professor Emerita of Microbiology and Pathology, 
                  New York University Langone Medical Center
                   
                  Victor Nussenzweig, Research Professor of Pathology, Professor Emeritus of Pathology, New York University Langone Medical Center
                   
                  Tu Youyou, Professor and Director of the Qinghaosu Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
                   
                   

                  LEADINGAGE HACKFEST

                  • October 30-November 1, 2015 
                  • UMass, Boston

                  LeadingAge has opened the application period for the 2015 LeadingAge HackFest, their annual event that challenges participants to “Engage with Age” by creating a technology-driven tool aimed at improving the lives of older adults and their families. Anyone with an interest in technology (you don't need to be a computer programmer) is encouraged to apply.

                  A Youtube video about the event is available here.   

                  Details about the event and an application to participate can be found at:  http://leadingagehackfest.org/

                   

                  PARTNERS HEALTHCARE CONNECTED HEALTH - 12TH ANNUAL CONNECTED HEALTH SYMPOSIUM

                  • October 29-30, 2015 
                  • Seaport Hotel & World Trade Center, Boston
                  This year's theme is The Internet of Healthy Things: Integrating Connected Health into Real World Care Delivery. The Symposium is a change-agent conference that promotes innovative thinking and the application of personal consumer health technologies to support new models of health care delivery.
                   
                  The Symposium consistently convenes a multi-disciplinary, diverse audience of 1,000 health leaders world-wide:  hospital executives, community-based MDs, health plan leaders, Fortune 500 employers, policy makers, researchers, technology developers, leading investors, patients, and advocates.
                   
                  Programming consists of TED style 20-minute keynotes, interactive panels, debates and interviews, demos of new and game-changing technologies, and an Exposition hall showcasing the latest global developments and innovations.
                   
                  For more information and to register, please visit the Symposium website:

                   

                  MEDTECH BOSTON INFORMATION SOURCE & CALENDAR OF EVENTS 

                  Boston has long been known as a medical mecca of scientific discovery. Boston’s healthcare professionals and administrators are adopting practices from other high-risk and service industries. The ‘big data’ movement is thriving, fundamentally changing our healthcare delivery systems. Digital health investments are higher than ever before. Medical hackathons and un-conferences are now an every-weekend occurrence. And both redesign and innovation promise to change medicine as we know it. It’s all happening right here, right now.

                  But the problem is that many of us don’t know it. Despite Boston’s innovative energy and a solid medical infrastructure, many medical providers and health care entrepreneurs remain in the dark about the opportunities, events and work happening in and around the city of Boston – and across the country. That’s where we come in.
                   
                  At Medtech Boston, we highlight exciting medical innovation work in and around the city of Boston. We aim to start a discussion about the most exciting and controversial new healthcare offerings, igniting a new reputation for Boston as a city with first-class medical research and patient care, but also as a city full of passionate people who use new technology to think big thoughts about medicine’s most pressing problems.
                   
                  More information and events from Medtech Boston is available here.
                   
                   

                  MIT GLOBAL HEALTH AND MEDICAL HUMANITIES INITIATIVE (GHMHI) UPCOMING EVENTS

                  The goal of the Global Health and Medical Humanities Initiative (GHMHI) is to provide MIT students the training to analyze critically the determinants of health and roles of medicine in society from historical and cross-cultural perspectives.

                  Global Health programs in medical schools, schools of public health, and universities and colleges across the U.S. emphasize how biomedical training, research, and practice, as well as interdisciplinary collaborations beyond the health sciences, are necessary to improve the determinants of health—whether social, political, economic, or biological.
                   
                  Medical Humanities is a subfield of medicine that draws on the humanities, arts, and social sciences to analyze medical education and clinical practice.
                   
                  Find more information and a calendar of upcoming events at http://ghmhi.mit.edu/.
                   
                   

                  HMS JOINT PROGRAM IN NUCLEAR MEDICINE (JPNM): NUCLEAR MEDICINE AND MOLECULAR IMAGING SEMINAR SERIES

                  The HMS JPNM offers a weekly seminar series from September through May/June.
                   
                  Seminars are held on Thursdays at 8:00 am in the Cannon Lecture Hall, HMS Quad, Building C
                   
                  S. Ted Treves, MD, Program Director, ted.treves@childrens.harvard.edu
                   
                  If you would like to be added to the weekly email distribution list for the lectures, please contact:
                  Ryan Hewitt, JPNM Program Administrator, rthewitt@partners.org (617-278-0702)
                   
                  Upcoming Seminars:
                   
                  Stay tuned for Fall 2015 seminar information.

                   
                  BRAINMAP SEMINARS

                  Future topics will be similar to the previous Brainmap season, with some talks on Optogenetics, MR-PET, BOLD physiology, ultra-high field MRI, multimodal integration, contrast agents, and many more exciting topics!
                   
                  Unless otherwise noted, seminars are held on Wednesdays at noon in seminar room CNY2204, MGH/Charlestown, Building 149.
                   
                  To sign up for the mailing list, please go to: https://mail.nmr.mgh.harvard.edu/mailman/listinfo/brainmap
                   
                  October 7, 2015 
                  Marta Peciña Iturbe, MD, PhD, Research Assistant Professor, Department of Psychiatry and Depression Center, University of Michigan
                  Molecular and Functional Mechanisms of Placebo Effects: Towards the Validation of Biomarkers in Clinical Trials
                   
                  October 14, 2015
                  R. Matthew Hutchison, PhD, Postdoctoral fellow, Department of Psychology, Harvard University
                  Do you see what I see? Brain responses to free viewing of dynamic social and non-social object interactions
                   
                   
                   

                  Student Opportunities
                   

                  LET'S CHAT PROGRAM
                   
                  A new program has started that is designed to help students who may be in need of support and direction, but who are reluctant to visit MIT Medical, or engage with S^3 or ODGE.  
                   
                  Called “Let’s Chat,” this outreach, which was originally announced by Cindy Barnhart in her recent message about various student support initiatives, offers a drop-in counseling office two hours daily from Tuesday through Thursday each week, in 8-316.  Students who want a low-energy-barrier way to talk to someone can sign up for one of several 20-minute sessions available from 1-3 pm Tuesdays through Fridays.  The goal is to make it as easy as possible for students to reach out for help they might need, so no advance appointment is necessary; students sign up for a 20-minute time slot by simply marking an “X” on one of the designated times on the daily schedule, which will be posted outside the door to 8-316.  
                   
                  This service will be staffed by clinicians from Mental Health, and is open to ALL students — graduate, undergraduate, any department.  Urgent situations should continue to be routed to MH walk-in or urgent care; “Let’s Chat” will focus on listening to students taking the first step to request support, and on providing referrals when necessary.
                   
                   
                  MIT $100K PITCH COMPETITION
                   
                  Applications are open for the MIT $100K Pitch Competition
                   
                  Apply now for the first phase of the 2015-16 MIT $100K Entrepreneurship Competition.
                   
                  Pitch is an elevator pitch competition. NEW this year: submit your best idea for a start-up in a 90-second video posted to YouTube. Industry experts will judge the entries.
                   
                  The teams who best articulate how they will create and capture value will move on the Final Round. Finalists will pitch in front of a live audience and jury on Wednesday, October 28 and compete for the chance to win $4,000. 
                   
                  More information is available at www.mit100k.org. The deadline for applications is October 2, so don’t delay.
                   
                   
                  LUCE SCHOLARS PROGRAM
                   
                  Don't miss the fellowship deadline on Thursday, October 22nd for the Center for International Studies (CIS) administered Luce Scholars Program.
                   
                  The Luce Scholars Program is open to seniors, graduate students, alumni from recent classes and junior faculty.  It places young scholars from a wide variety of intellectual fields in 10-month internships in selected countries in Asia. Those who already have significant experience in Asia or Asian studies are not eligible for the Luce Scholars Program. Candidates may have taken Asian language or Asia-focused courses on a U.S. campus (without majoring in Asian Studies). They may have spent up to a total of twelve weeks, or have participated in a university-organized summer program, in one or more countries where Luce Scholars are placed. If in doubt as to whether your prior experience disqualifies you, please contact me. Nominees must be American citizens not yet 30 years old on July 1, 2016 and who have earned at least a bachelor's degree or expect to receive one by July 1, 2016.
                   
                  Prospective MIT candidates must apply through CIS. MIT/CIS is permitted to forward THREE applications this year to the Luce Foundation. Applications must be received by CIS by Thursday, October 22nd.
                   
                  More information is available online at http://web.mit.edu/cis/fo2_5.html.  Many of your questions can be answered on the FAQ page http://www.hluce.org/lsquestions.aspx
                   
                  The Application Form is also available for download online as a Word document: http://www.hluce.org/lsapp.aspx
                   
                   
                  EDMOND J. SAFRA GRADUATE FELLOWSHIPS IN ETHICS 2016-2017
                   
                  Applications are invited from graduate students who are writing dissertations or are engaged in major research on topics in practical ethics, especially ethical issues in architecture, business, education, government, law, medicine, public health, public policy, and religion. The Center seeks applicants who have excelled in their fields of specialization, have demonstrated an interest in questions of value that cut across disciplinary boundaries, and who are likely to make significant contributions to teaching and scholarship in practical and professional ethics. Students should either be enrolled in a Harvard doctoral program; enrolled in or a recent graduate of a Harvard professional degree program that does not require a doctoral dissertation for an academic career (such as law or medicine); or a current Harvard affiliate who is engaged in postgraduate training or in graduate training at another school and has no commitments in 2016-2017.  Advanced students taking leaves of absence from one of these approved programs are also eligible. All course requirements and general examinations must be completed before the start of the fellowship year. Students taking a full or partial course load in either semester of the fellowship year are ineligible. 
                   
                  Deadline: November 16, 2015
                   
                  For more information, please view our website: http://ethics.harvard.edu/pages/graduate-fellowships.
                   
                  Questions about the Graduate Fellowship program can be directed to Emily Bromley (emily@ethics.harvard.edu)
                   
                   
                   
                  GRADUATE RA: NEUROENGINEERING IN TRANSLATIONAL RESEARCH
                   
                  A neuroengineering RA position is available in the Poon Lab for translational research that combines engineering control theory and neuroscience approaches in solving clinical problems. Will work with basic neuroscientists and clinicians in several multidisciplinary projects seeking improved treatments of patients who are on mechanical ventilation in the ICU or patients with obstructive sleep apnea (heavy snoring); diagnosis and treatment of patients with a rare neurological disease called Rett syndrome; diagnosis and treatment of patients with chronic obstructive pulmonary disease or heart failure; and others.
                   
                  Below is a description of one of the ongoing projects. Details of other projects available upon inquiry.
                   
                  An excellent opportunity for talented/motivated students interested in biomedical devices to assist in adapting a newly patented ‘smart’ mechanical ventilator (http://www.google.com/patents/US20090194110) which has been FDA-approved for experimental testing in a clinical study that is underway at MGH. This collaborative project between MIT and MGH is sponsored by the National Institutes of Health and a major biomedical device company (Covidien/Medtronic). Work may lead to a SB / Master’s thesis and possible scientific publications down the road. 
                   
                  Requirements:  Familiarity with Matlab programming is essential. Background in biomedical devices, control systems, signal processing, physiology is helpful. We are dealing with real patients who are under critical care in the ICU – strong student commitment is a must!
                   
                  Responsibilities:  Adapt an existing computer program written in Labview (a Matlab-based software package) for real-time data acquisition and control of a mechanical ventilator currently interfaced to a patient simulator and port it to new platforms suitable for concurrent testing in an animal study (at MIT) and a clinical study on patients in the ICU (at MGH). Interact with research scientists and clinicians carrying out those studies and provide technical support to facilitate those studies. Refine the program to improve its functionality.
                   
                  Contact:  Dr. Chi-Sang Poon at Institute for Medical Engineering & Science, cpoon@mit.edu.
                   
                   
                  PARTICIPANTS SOUGHT FOR PROJECT IN TELEMEDICINE/TELEHEALTH
                   
                  Term: Fall 2015 with option to continue during Spring 2016
                  Department/Lab/Center: IMES
                  Faculty Supervisor: Visiting Professor Amar Gupta
                  Project Title: Global Health, Telemedicine, and Multi-Pronged Approach
                   
                  Project Description:
                  Telemedicine/telehealth is poised for double digit growth and widespread adoption within the next decade. The remote delivery of healthcare services, fueled by advances in communication and mobile health technologies, has been shown to provide improved outcomes and quality at a reduced per-capita cost. In the wake of the Affordable Care Act, this shift motivates research into both technical and non-technical aspects of telemedicine from the first stage of the patient/physician connection to the later stages of nationwide telehealth data systems.
                   
                  This project provides opportunity for multiple students to be involved to study technical, business, policy, and public health issues.  Previous researchers have published their findings in technical, business, medical, and legal journals.  The focus and scope of the activity can be tailored to the background and interest of the concerned student.
                   
                  Specific projects include: (i) integrating and analyzing medical data from heterogeneous systems and formats; (ii) proposing new systems for nationwide telehealth data systems; (iii) identifying technical solutions to current barriers in evolving telemedicine concepts; (iv) assessing telemedicine prototype systems that have been deployed in various parts of the world; and (v) analyzing the effects of divergent and patchwork regulations in various U.S states.
                   
                  Contact: Interested applicants should submit a recent resume to Professor Amar Gupta at agupta@mit.edu. Please include the preferred number of hours you would like to devote each week to this activity, and a brief statement of the subset of the 5 potential activities (listed above) that interest you. Students can potentially receive academic credit for this work, or use this work as part or complement to their doctoral or masters research in medical field.
                   
                   
                  PATEXIA - APPLIED RESEARCH OPPORTUNITIES FOR ENGINEERING STUDENTS

                  What we do…

                  Patexia is a Los Angeles-based startup that uses crowdsourcing to solve engineering and innovation challenges for some of the largest technology companies and research-oriented organizations in the world. We were recently awarded a contract through the NASA Tournament Lab and we are looking for talented undergraduate and graduate engineering students to join our network as problem solvers and campus ambassadors. 
                   
                  Applied research opportunities…
                   
                  Technical Problem Solver
                   
                  The strength of Patexia’s crowdsourcing model comes from the global community of over 10,000 technical problem solvers and subject matter experts behind it. By joining our professional network as a student member you will have the chance to interface with top companies and research organizations in your field as you develop innovative solutions to real world challenges. Throughout the process you will be collaborating with classmates, professors, and experts from around the globe as you compete against teams from other US and international universities for bragging rights and cash prizes.
                   
                  Campus Ambassador
                   
                  As a bridge between industry-driven problems and university-based solutions, we need to work with the very best in order to exceed the expectations of clients such as NASA and Cedars-Sinai Medical Center. The Patexia campus ambassador program is built around well-connected engineering students who can not only help us solve technical problems, but can share their experience with classmates, friends, and professors to help expand our reach. Campus ambassadors will regularly meet and train with the Patexia team and, in addition to compensation for meeting defined recruitment goals, ambassadors will be invited to relevant networking events and be given the opportunity to directly connect with important industry contacts.
                   
                  How you can get involved...
                   
                  If you are interested in collaborating with Patexia as a problem solver, campus ambassador, or both please contact us at ambassador@patexia.com. You can also read more about the perks of the ambassador program here on Patexia.
                   
                   

                  MIT ENGLISH AS A SECOND LANGUAGE VOLUNTEERS NEEDED

                  The MIT English as a Second Language Program for Service Employees is looking for volunteers to tutor night shift employees for 1-2 hrs/wk or to serve as substitutes as needed for the Fall semester that runs from September 28 - December 11, 2015.
                   
                  No experience is required, just a good command of English and an interest in helping individuals whose first language is not English. The goals of the program are to build student’s confidence, to help them become more productive in their jobs, and to perhaps open up further opportunities for advancement.
                   
                  Tutoring takes place on Tuesdays and Thursdays from 11pm - midnight beginning September 28.

                  This is an opportunity to make a real and positive difference..
                   
                  Please contact esl-admins@mit.edu for details.

                   

                  APPLICATIONS OPEN - 2016 CLASS OF PAUL & DAISY SOROS FELLOWSHIPS FOR NEW AMERICANS

                  Applications are now open for the 2016 Class of Paul & Daisy Soros Fellowships for New Americans. The Paul & Daisy Soros Fellowships are open to immigrants and the children of immigrants who are entering or have begun graduate school. Fellows receive up to $90,000 in support of their education: $40,000 in tuition support and $50,000 in stipend support over two years. More importantly, they join a lifelong community of New Americans who are making significant contributions to society.
                  For full eligibility requirements, to register for a web info session or to apply, go to: www.pdsoros.org

                   

                  UPCOMING FELLOWSHIP OPPORTUNITIES - ODGE 

                  Generous donors have provided MIT with permanent funds in support of fellowships, many of which have unique restrictions. The Office of the Dean for Graduate Education administers a number of these endowed fellowships through an annual competition in March. All nominations (both for new awards and for renewal requests) must be submitted by the departmental graduate office on behalf of the student. Students who qualify for one of the fellowships should contact their graduate administrator in order to be considered for
                  nomination.
                   
                  More information may be found here. 
                   
                   
                  GRADUATE COMMUNITY FELLOWS PROGRAM POSITIONS AVAILABLE

                  Some openings are still available for the Graduate Community Fellows program in the Office of the Dean for Graduate Education!

                  Graduate Community Fellows are a cadre of graduate students who work on projects and assignments that enhance the MIT graduate
                  community in unique ways.  Each Fellow reports to a staff member in the Office of the Dean for Graduate Education or in a partner organization, and focuses on a specific project.  Fellows receive partial stipend support for the length of their appointment period. 

                  Open positions are as follows:

                  • Institute Community and Equity Office (one position open for 2015-16)
                  Please see our web site for position descriptions and an application form (http://odge.mit.edu/community/gcf/).
                  We are accepting applications now and will fill positions on a rolling basis.
                  Receive a monthly stipend while you gain experience.  Apply now!
                  Questions? Contact Heather Konar (konar@mit.edu)

                   

                  COMMUNITY SERVICE WEEKLY BULLETIN

                  At the heart of the MIT mission statement is a call to serve the nation and the world—and this charge is embodied by the MIT Public
                  Service Center. Every year, we send thousands of students into communities locally, across the nation, and around the globe to apply their skills and knowledge for the betterment of humankind. In the Institute's best traditions of hands-on experience, entrepreneurial spirit, and creative problem solving, these students donate their time, create new technologies, form communities and companies—and ultimately change lives everywhere they go.
                   
                  As part of MIT's Division of Student Life, we provide a central point of communication and support for the outreach and humanitarian
                  efforts of the MIT community. We engage students, alumni, staff, faculty, and others in life-changing initiatives and social entrepreneurship ventures that provide needed resources to individuals and communities.
                   
                  Sign up for the weekly Community Service Bulletin of Events and Programs here.
                  News and upcoming events are posted on the homepage.

                   

                   


                  Professional Opportunities

                   

                  POSTDOC POSITIONS IN BIOINFORMATICS & MOLECULAR BIOLOGY (FREIBURG, GERMANY)

                  Two new fully-funded postdoctoral fellows - one with strong bioinformatics expertise as well as one with a background in molecular biology/RNA biology/cancer research are available at the German Cancer Consortium (DKTK) Freiburg.

                  More information on both of these positions can be found here:

                   

                   
                   

                  TECHNICAL ASSISTANT (KARP LAB)

                  Translational Mucosal Biology & Drug Delivery: Karp Lab / Langer Lab, Boston, MA, USA

                  The Karp Lab at Brigham & Women’s Hospital, Harvard Medical School, and the Langer Lab at the Massachusetts Institute of Technology aim to rapidly advance therapeutic solutions for diseases in oral and gastrointestinal mucosa through multidisciplinary approaches. A major focus between our research groups is to develop technologies that can be rapidly translated to the clinic to improve the quality of life of suffering patients.
                   
                  This technical assistant will help developing stem cell/small molecule based therapeutic systems for mucosa-related diseases. The candidate for this position will be responsible for stem cell culture, small molecule screening, cell-based assays, animal studies and data analysis. The candidate will have strong organizational and communication skills for assisting technology innovators, engineers, biologists, and clinicians in a dynamic team environment.
                   
                  Basic Qualifications: 
                  • Bachelor or Masters degree and relevant experience in Biology, Bioengineering, Biomedical Engineering, Biochemistry or related fields. 
                  • Ideally will have ample experience in cell culture; cell-based assays; small molecule screening; molecule biology and animal studies.
                  • Candidates should be allowed to work in the USA.
                  The Karp and Langer Labs are dynamic and fast paced environments that thrive on collaboration and ingenuity. We have a diverse, international talent pool, simultaneously working on multiple projects across several disease areas. We are focused on the development of platform technologies supporting a broad range of potential applications in medicine and bioengineering. Our emphasis on translational research enables us to train the next generation of bioengineers and expand the boundaries of this exciting field. We seek members with highly developed interpersonal skills who could contribute to our dynamic lab community.
                   
                  Interested candidates should email: jmkarp@partners.org and include a cover letter expressing interest and their updated CV with a list of publications.
                   

                   

                  MOORE-SLOAN FUNDED POSTDOC POSITION IN DATA AND HEALTH

                  A Moore-Sloan funded Post-doctoral opportunity in developing novel computational approaches for disease surveillance is available at the Laboratory of Dr. Rumi Chunara in Computer Science & Engineering, and the College of Global of Public Health at New York University. We are seeking a highly motivated researcher interested in developing and studying new computational methods for using Internet and mobile connected data sources to understand disease in populations worldwide. The postdoctoral fellow will be part of and leverage the vibrant Moore-Sloan Data Science environment at NYU (and Berkeley and UW) which includes numerous faculty and pertinent events.

                  Ideal candidates will have a Ph.D. with a strong background in computer science, statistics, bioinformatics, or related field. Preferred requirements for this position include experience designing software applications and/or storing, retrieving, and analyze large datasets. Experience with R, Python, SQL, JavaScript is preferred. Experience in hacking with cloud technologies (e.g., AWS, Hadoop) is a big plus. You must demonstrate an interest or experience in working with biological data such as genomic sequence, syndromic surveillance or physiological data.
                  This is an exciting research area and New York City provides great opportunities for networking and support of innovative work. Our group is engaged in many high-profile studies in collaboration with startups and other groups. The selected post-doc will be supported and encouraged to generate high impact publications, gain experience in supervising students and in grant writing if interested. All applicants should send a CV to Rumi Chunara (rumi.chunara@nyu.edu). The position is available immediately.

                   

                  PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE: OPEN FACULTY POSITIONS

                  The School of Engineering, the School of Medicine and the Faculty of Biological Sciences of the Pontificia Universidad Católica de Chile invite applications for two full-time faculty positions in the areas of Biomedical Devices, and Bioinformatics and Computational Biology. The candidate will join other full-time faculty and several part-time appointments in the recently established Institute for Biological and Medical Engineering, dedicated to research and teaching in the areas of Biomedical Imaging and Modelling, Bioinformatics, Systems Biology, Synthetic Biology, Biotechnology, Biomechanics, and Biomaterials.

                   

                  VL34 - SCIENTIST/SENIOR SCIENTIST IN MOLECULAR BIOLOGY

                  VL34, Inc. has an immediate opening for a Scientist/Senior Scientist in molecular biology.  VL34 is an early-stage startup in Cambridge, MA using cutting-edge molecular techniques to help create a novel category of fertility treatment. VL34 was founded by VentureLabs, a unit of Flagship Ventures which has launched over 25 breakthrough companies including Seres Therapeutics, Symbiota, Pronutria, and Moderna Therapeutics. 

                  Position Summary
                  VL34, Inc. is seeking an exceptional, highly motivated Scientist/Senior Scientist to play a key role in the company’s efforts to build a high-throughput platform to identify molecular targets with applications in the fertility field.  As part of the early team of scientists at VL34, this individual will have wide-ranging responsibilities, joining a dynamic, enthusiastic, highly interdisciplinary, and collaborative group.
                   
                  Key Qualifications
                  Ph.D. in Biology or a related field, with or without postdoc or industry experience 
                  Ability to think critically and creatively as part of a fast-paced research team
                  Proven hands-on experience with standard molecular biology techniques.
                  Especially preferred to have experience with one or more of:
                  oCustom library preparation for high-throughput sequencing, single cell or low-input detection
                  oProtein engineering, library-based display technologies (yeast, phage), in vitro directed evolution and selection
                  Enthusiasm for pushing the frontiers of conventional techniques and comfort in venturing beyond one’s area of expertise
                  Great hands in the laboratory and resourceful when starting new techniques from scratch
                  Excellent collaboration, communication and interpersonal skills

                  Responsibilities
                  The successful candidate will work closely with an interdisciplinary team as well as independently to design and execute experiments that support research activities and project goals
                  Quickly implement state-of-the-art techniques in new biological models
                  Identify modifications to iteratively improve protocols
                  Analyze data and help identify molecular targets and follow-up experiments
                  Participate in various aspects of the company from establishing collaborations to writing patents to long-term planning
                   
                  Compensation
                  A competitive overall compensation package including: competitive base salary, bonus potential and stock options.
                   
                  Contact Information
                  To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Brian at VL34Jobs@gmail.com.

                   

                  PURETECH - SENIOR ANALYST

                  About PureTech

                  PureTech is a science-driven healthcare company, seeking to solve some of today’s toughest health challenges through disruptive approaches. Based in Boston, PureTech has a network of more than 50 experts across multiple disciplines – from entrepreneurs to world-renowned scientists – giving PureTech access to potentially groundbreaking science and technological innovations. PureTech is problem-focused and solution-agnostic, looking beyond traditional disciplines and approaching healthcare problems from different perspectives. Focusing on areas of significant unmet medical need, PureTech evaluates more than 650 ideas per year, prioritizing, testing and selecting what it believes to be the most scientifically and commercially promising concepts to advance.
                   
                  Job Description:
                  The Senior Analyst will get hands-on experience in entrepreneurship, participate in sourcing and due diligence of technologies and support PureTech's Innovations and team members. This includes:
                  Ideation and business planning for next generation technologies
                  Conducting strategic analyses & market opportunity assessments
                  Undertaking project management & operations of innovations including development of cutting edge technologies
                  Participating in analysis and development of intellectual property
                  Preparing compelling communication materials, including presentations, for key external stakeholders
                   
                  Qualifications:
                  Creativity, smarts & initiative
                  PhD in one of the following disciplines from a top tier institution: engineering, physics, computer science, or a life sciences related field
                  Business experience is a plus but not required
                  Strong presentation and communication skills; candidate should feel comfortable presenting to groups
                   
                  Location: Boston, Massachusetts
                  The position is full time with a competitive salary and benefits. This is a unique opportunity to join one of the most innovative companies in healthcare while getting hands-on startup experience in our Innovations. Please send your resume and cover letter to careers@puretechhealth.com. Be sure to indicate the Senior Analyst Position in the subject of your email.  (E-mail applications sent directly to PureTech staff will not be considered)

                   

                  POSTDOCTORAL FELLOW POSITION – MCLEAN HOSPITAL/HARVARD MEDICAL SCHOOL

                  A NIDA sponsored T32 Postdoctoral Position is available in a multidisciplinary, productive and stimulating environment with excellent research, clinical and training resources. Applicants, especially those with a background in brain imaging analysis/statistical methods, are encouraged to apply. The focus of the training is on brain imaging (EEG, MRI, MRS, near infrared spectroscopy) for research on psychiatric and substance abuse disorders and the program will be tailored to meet individual needs in order to help him/her to develop into an independent researcher with a focus on neuroimaging of addiction or addiction psychiatry. Fellowships are available for 2-3 years, with an appointment at Harvard Medical School. M.D., Ph.D. or an equivalent degree in physics or medical physics, computer science, neuroscience, psychology, pharmacology or related field is required. Minorities and women are strongly encouraged to apply. Start date is flexible, with one position available now; salary is commensurate with experience.  Candidates must be US citizens or hold a green card.

                  Inquiries from individuals with analysis/statistics experience may be made to Lisa Nickerson, Ph.D., Director, Statistical Neuroimaging in Addiction and Psychiatry Lab (lisa_nickerson@hms.harvard.edu). Other qualified applicants may contact the Director of the T32 Program, Dr. Scott E. Lukas (slukas@mclean.harvard.edu).

                   

                  RESEARCH AND DEVELOPMENT SCIENTIST POSITION

                  Aptitude Medical Systems Inc. – Santa Barbara, CA

                  Contact: Jackson Guo, CEO of Aptitude Medical Systems (jackson@aptitudemedical.com )
                   
                  Summary
                  There is currently a massive unmet need to target specific biomolecules. This problem holds back humankind’s ability to diagnose and treat diseases. At Aptitude, we create a new generation of affinity molecules that can function where antibodies cannot, enabling new diagnostic and therapeutic products. We are at the forefront of the technical revolution, uniquely enabled by our breakthrough technology - the culmination of a decade of multi-disciplinary research in the H. T. Soh lab at UC Santa Barbara. We have received significant funding from venture investors and federal grants, and formed key collaborations with multiple top companies in their respective fields to rapidly deploy our technology in clinical applications. As we enter the growth phase of the company, we are looking for first-rate Research Scientists to join a fast-expanding team.
                   
                  Why Choose Aptitude
                  We view A-level team members as our most precious resources, and will treat them as such. We will gladly support work visa applications, help with relocation, and make many other accommodations according to the new employee’s circumstances.
                  We have a culture of quickly recognizing the contribution and enabling team members to “punch above their weight class”. If your competency and desire to succeed goes beyond your resume, we can provide the platform that let you fulfill your potential, create extraordinary value, and get rewarded accordingly.
                   
                  Responsibilities
                  The following is not an exhaustive list of responsibilities. In this highly dynamic working environment, other duties and responsibilities will be added.
                  • Develop, test, and optimize aptamers, assays and other products
                  • Design and execute experiments; process, analyze, and interpret experimental results and data
                  • Maintain accurate, consistent, high quality project documentation; present results to senior/other research staff
                  • Create or assist with creating technical reports, white papers, publications, and technical proposals; facilitate external communication in conference presentations, customer dialogs, etc.
                  • Develop original solutions to problems and create new experimental strategies
                  • Help set project goals, milestones and continuously track progress and success
                  • Prioritize and manage technical tasks for concurrent projects
                  • Help and support other project teams or groups when needed
                   
                  Knowledge, Skills, and Abilities Required
                  The four fundamental characteristics that we need on the team are:
                  • Willingness to take on any responsibility to enable the team to achieve success
                  • A sense of urgency and ability to achieve time-sensitive milestones
                  • Persistence to work through challenges and unlock both systematic and creative solutions 
                  • Transparent. That is, honest and open in all matters to maintain a culture of trust, without politics, and the capacity to uncover problems and address them rapidly.
                   
                  In addition, we look for the following skills and abilities in top candidates:
                  • Motivated self-starter who has desire to be challenged and is looking to continually advance within the organization
                  • Meticulous attention to detail, executing with high accuracy and reproducibility
                  • Independent and logical thinking with demonstrated analytical skills in problem analysis and resolution
                  • Strong theoretical base in relevant subjects (e.g. biothermodynamics, binding and kinetics, statistics)
                  • Expertise in standard lab methods (e.g. PCR, western blotting, flow cytometry, ELISA), and solid understanding of fundamentals behind each
                  • Proven ability to mange own time effectively to achieve milestones with aggressive deadlines
                   
                  Education/Experience Required
                  Different combinations of experience and educations will be considered for qualification of this position:
                  • Degree in bioengineering, chemical engineering, materials engineering, chemistry, biochemistry, or molecular biology with relevant expertise
                  • At least four years of work-related experience in a relevant laboratory environment
                  • A PhD or MSc/MA in relevant specialization is favorable, but not necessary. If you have the drive and ability to create real and growing value on the Aptitude team we will give you every opportunity to grow and advance into senior roles.

                   
                  PORTAL INSTRUMENTS POSITION AVAILABLE

                  Lead Firmware Engineer
                   
                  About Portal Instruments: Portal Instruments is an early stage, Series A funded, medical device company focused on advanced drug delivery and backed by powerful strategic partners. The company is commercializing a highly innovative needle-free drug delivery platform technology developed at MIT transforming the administration of injectable medicines. Patients suffering from chronic diseases need to inject themselves several times per month via needles and syringes. This poses challenges in terms of comfort, safety and compliance. Portal’s device, which is augmented by connected health features, dramatically improves the patient experience and ultimately transforms disease management leading to better outcomes. 
                   
                  Working at Portal Instruments:
                  • Portal Instruments is looking for unique individuals who want to make a difference in the lives of patients and how medicines are delivered today
                  • Portal Instruments offers employees the opportunity to work in an exciting  fast-paced environment that values best in class ingenuity, intellectual curiosity, teamwork, and a commitment to results while providing outstanding leadership and development opportunities
                  • Portal Instruments is an equal opportunity employer offering a competitive salary, a comprehensive benefits package, including stock options, a 401(k) retirement plan, a health and dental plan and a chance to make a difference in the lives of thousands of patients.
                  Role and Responsibilities:
                  • Design firmware system architecture for Portal’s novel drug delivery platform from concept through commercialization with due consideration to reliability and regulatory concerns
                  • Design, build, debug, and optimize the device’s firmware
                  • Manage the software development lifecycle consistent with FDA requirements, including the creation of specifications, validation and other documentation as needed.
                  • Integrate with a team of firmware, software, and control engineers.
                  • Design, build, debug, and optimize firmware
                  • Evaluate system performance by designing, executing, and documenting experimental plans.
                  • Support the risk management process using FMEA/FTA and other risk mitigation techniques.
                  • Support electrical compliance testing.
                  • Support the manufacture and testing of electronic assemblies by providing test procedures
                  • Support cost and manufacturability improvements through collaboration with Hardware, Manufacturing and Procurement teams.
                  Required Skills and Experience:
                  • Development of efficient microcontroller firmware in C, preferably ARM.
                  • Familiarity with quality system requirements for medical software system development.
                  • Experience with control systems required. Knowledge of system identification techniques and non-linear controls a plus.
                  • Experience with high-bandwidth motion control.
                  • Sensor synthesis / sensor fusion.
                  • Familiarity with electronic hardware design.
                  • Automated integration testing of firmware.
                  Qualifications:
                  • Degree in Electrical Engineering, Computer Engineering, or equivalent engineering discipline.
                  • 5+ years of experience in commercial development and/or validation.
                  • Experience with medical products development and FDA or related product approvals a plus.
                  • Outstanding software engineering and design skills.
                  • Working knowledge of UL, FCC, and CE/ISO standards and test methods.
                  • Applicant should be comfortable in C, LabVIEW, Verilog or VHDL, an assembly language (THUMB2 preferred), and a scripting language (Python preferred).
                  • Ability to work independently in a start-up environment.
                  Salary commensurate with experience; potential equity participation.
                   
                  To Apply: Please submit a resume and cover letter to careers@portalinstruments.com, please reference job code RD06. You will be contacted if your background meets our needs.
                   

                  10X GENOMICS - POSITIONS AVAILABLE

                  10X Genomics is a San Francisco Bay Area start-up developing new technologies for breakthrough next generation sequencing applications. The core technology combines advances in chemistry, biochemistry, microfluidics and computational biology.

                  Applications Scientist: Computational Biology
                  10X is looking for an outstanding individual to join its Computational Biology group. This person will primarily: (1) work with the product development team to assess early developed modules and integrated prototypes and (2) work with 10X’s first set of collaborators and customers, serving as a vital bridge between these customers and the development team. The main responsibilities will include: (1) working w/ early collaborators to explore new applications of the system, (2) prototyping new computational methodologies to support these novel uses, (3) developing custom analyses to support customer applications and (4) analyzing the performance of the core components of the 10X technology for feedback into the development team. This position is a unique opportunity to work on an exciting and novel form of NGS data that enables a wide array of previously unachievable applications.
                   
                  Computational Biologist: Algorithm Development
                  10X is looking for an outstanding individual to join its Computational Biology group. This position is a unique opportunity to work on a new form of Next Generation Sequencing (NGS) data that enables many previously unachievable applications. This person will: (1) lead the development of algorithms that use 10X Linked-Read data to solve difficult genomics problems, (2) define custom analyses to guide product development. The ideal candidate will have experience implementing novel methods using techniques such as sequence alignment, text indexing and searching, graph algorithms, combinatorial optimization and probability theory. Experience combining novel and existing tools into effective pipelines is a plus.
                   
                  Computer Scientist: Algorithm Development
                  Our San Francisco Bay Area startup is completely changing how DNA sequencing is done. Our breakthrough technology combines advances in chemistry, biochemistry, microfluidics, engineering, computational biology and software. Our small team consists of leaders in these fields who will make further fundamental advances, positioning our product as a foundation for all of medicine and biology. We have just shipped version 1.0. Our environment: as good as it gets.
                   
                  We now seek an outstanding individual to invent algorithms for reconstructing an organism’s genome from the billions of DNA fragments created by our technology. The position does not require background in this problem per se. Rather we seek an innovator with a track record in solving other nearly impossible problems, who can bring general tools to bear, who thrives in an edgy, fun, team and interdisciplinary environment. The position requires mathematical and algorithmic sophistication, the ability to rapidly turn ideas into code, test this code on evolving data, adapt accordingly, and learn continually by interacting with colleagues in multiple fields. We are a nice team of people who are simply the best at what we do.

                  Data Scientist
                  10X is looking for an outstanding individual to join its Computational Biology group. This person will lead the development of analytical frameworks and computational methods for investigating the error modes of all components of the core technology and the impact of these on application performance. These analyses will drive the prioritization of technology development within thecompany. This position is a unique opportunity to work on an exciting and novel form of Next Generation Sequencing (NGS) data that enables a wide array of previously unachievable applications.
                   
                  For more information about the company and to see the job listings, visit: 10xgenomics.com/company

                  To apply for a position please contact jobs@10xgenomics.com

                   

                  POSITIONS IN ZUBER/CARR/RUVKUN LABS IN GENOMICS/ASTROBIOLOGY/BIOASTRONAUTICS

                  Graduate Research Assistant: Contribute to an integrated genomics platform for life detection beyond Earth. This NASA-funded effort, the Search for Extra-Terrestrial Genomes (SETG, setg.mit.edu), has the potential to provide the first direct evidence for life on Mars and on icy moons, as well as enable diverse environmental and clinical applications. Opportunity to 1) develop, evaluate, and integrate technologies for bioseparation and sequencing, including nanopore-based single molecule approaches, to 2) design, develop, and validate the instrument in the lab, and in the field at terrestrial analogs of Mars or other extreme environments. Responsibilities also include communicating results to the scientific community through publications and presentations.
                   
                  This position is physically based in the Department of Molecular Biology at the Massachusetts General Hospital. You will work closely with the Science PI, Christopher Carr (carrlab.org), in association with the project PI Maria Zuber at MIT, the MGH Institutional PI Gary Ruvkun, and other academic and industrial partners.
                   
                  Job Requirements
                  REQUIRED: Undergraduate degree in highly relevant field; strong analytical and problem solving skills. You must be highly motivated, technically excellent, able to work independently and contribute to an interdisciplinary team, and have excellent communication and interpersonal skills. Experience with molecular biology, high throughput sequencing, embedded systems, microcontrollers, mechanical design, thermal modeling, space instrumentation, and other relevant skills highly valued.
                   
                  How to Apply
                  Please send a CV and cover letter with the name and email of three references to chrisc@mit.edu with “SETG Research Assistant Application” in the subject line.

                   

                  RESEARCH ASSISTANT - ORTHOPEDICS ARTHROPLASY - MGH

                  Dr. Young-Min Kwon in the department of Orthopedics Arthroplasy at Massachusetts General Hospital is currently looking to fulfill an opening for a research assistant with an engineering background to work on a project studying in-vivo kinematics of joint replacements. More details about the project are listed below. It is a 40 hours per week self-funded position with a one year commitment. There will also be ample opportunities for clinical exposure during this period. Please email your CV to cwu22@mgh.harvard.edu.

                  Project Description: The demand for number of total hip replacement (THR) surgery for advanced arthritis is expected to double over the next decade. The past and current innovation of THR has largely focused on development of improved implant bearing materials and implant fixation methods. However, the challenges in the performance of contemporary THR are related to adverse in vivo dynamic phenomenon (such as edge loading, impingement and dislocation), which occurs as a function of both static implant orientation (cup positioning); and 2) dynamic biomechanics of the individual patient. This new innovative research aims to: 1) evaluate the utility of robotic–assisted surgical technology in improving acetabular implant orientation; and 2) quantify its role in optimizing in vivo biomechanics of hip joint is required to gain insights to overcome the current challenges. Student Role: Orthopaedic Research Assistant It is expected that the student will be involved in a study that will be performed to validate the utility of 1) the dual fluoroscopic system in evaluating in vivo kinematic parameters of hip joint; and 2) dynamic motion analysis combined with CT data in evaluating in vivo duration and magnitude hip joint force (kinetic parameters) during functional activities.”

                   

                  FDA JOB OPPORTUNITIES FOR MIT ENGINEERS

                  Lead Reviewer – Biomedical / Electrical / Mechanical Engineers

                  The FDA is seeking college graduates (biomedical, electrical and mechanical engineers) for entry-level reviewer positions at the Center for Devices and Radiological Health (CDRH) in the Division of Cardiovascular Devices.  There are several vacancies and candidates will be screened for interviews on a rolling basis until the positions have been filled.  Interested candidates including upcoming graduates are encouraged to apply as soon as possible.

                  Responsibilities:

                  1. Lead premarket scientific reviews in the Division of Cardiovascular Devices with teams of clinicians, engineers and interdisciplinary scientists and work closely with medical device manufacturers, clinical investigators, regulatory affairs managers and industry consultants; and
                  2. Conduct engineering reviews for marketing applications for ventricular assist devices, heart valves, stents, angioplasty catheters, endovascular grafts, occluders, pacemakers, ablation catheters, automated external defibrillators, cardiac monitors, mapping systems, and emerging cardiovascular therapies and technologies; and
                  3. Engage in all aspects of the total product life cycle: medical device design, bench tests, preclinical animal studies, clinical trial design, premarket review, manufacturing and post-market surveillance.
                  Preferred coursework, experience, or research: electronics, instrumentation; physiology, cardiac electrophysiology, biostatistics, medical imaging; reliability engineering; material science, biomechanics, cardiovascular research, senior engineering design projects.
                   
                  Desired skills: Strong engineering and critical thinking skills, excellent written and oral communication skills, comfortable working in dynamic team environments, and time management and organizational skills are essential for the position.  Knowledge of FDA regulations is highly desired, but not a requirement.
                   
                  Benefits: Stimulating, high-impact work environment, at the cutting edge of cardiovascular medical device technologies; flexible work hours and partial telecommuting arrangements available.  FDA reviewers receive full benefits as salaried federal employees.
                   
                  Level of Education: The job opening is available to graduates in bioengineering, biomedical engineering, electrical engineering, or mechanical engineering for entry-level reviewer positions.  Qualified candidates from other engineering disciplines will also be considered based on experience and coursework.
                   
                  Availability: Spring 2015 graduates and other recent graduates.
                   
                  Citizenship: Must be a United States citizen to be eligible for the position.  
                   
                  Location: The position is located at the FDA headquarters (pictured) in Silver Spring, Maryland in the Washington D.C. Metro Area.
                   
                  Application:  Please submit a CV/Resume and cover letter to DCDHiring@fda.hhs.gov Please note that due to the large number of applicants, only qualified candidates will be contacted for interview.
                   
                   

                  ACAMEDICUM.COM - WORLDWIDE LISTING OF NEW ACADEMIC AND CLINICAL VACANCIES

                  Academicum is an academic search firm specialising exclusively in contacting and assisting in the recruitment of professors, doctors, researchers and academic managers in the sector of medical schools and university hospitals worldwide.

                  We are pleased to present you the latest edition of the academic and clinical newsletter including our selection of the academic and clinical vacancies at Acamedicum.com - exclusively dedicated to careers in medical schools and university hospitals worldwide.

                  To learn more about these and other vacancies, we invite you to visit our website www.acamedicum.com and/or to "Register as a user or an active candidate" and/or to "Contact us".

                   

                  POSTDOCTORAL FELLOW POSITION - JAIN LAB

                  Postdoctoral Fellow in Signaling in Pediatric Brain Cancers, especially Medulloblastoma
                   
                  Description: Prof. Rakesh K. Jain is currently seeking a postdoctoral applicant with expertise in signaling transduction, molecular biology and cell biology. The position requires a highly motivated and independent researcher to carry out a project aimed at understanding the molecular mechanisms of Shh-PIGF-NRP1 signaling axis in medulloblastoma. Please see our recent paper: Snuderl et al., Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152: 1065–1076 (2013).
                   
                  Requirements: Applicants should send a CV, career statement and three letters of reference to: Rakesh K Jain, PhD, Director, Edwin L Steele Laboratories for Tumor Biology, Massachusetts General Hospital & Harvard Medical School, 100 Blossom Street, Cox Building 7th, Boston, MA 02114
                   
                   

                  IMMUNEERING - POSITIONS AVAILABLE

                  Seeking scientists who are passionate about developing & communicating new ways to extract biological insights from data, leading to better medicines for patients
                   
                  This role involves working closely with leading pharmaceutical companies, helping to facilitate the development of new medicines for serious diseases including neurodegeneration and cancer. The ideal candidate would have experience in one or more of the following areas:
                   
                  Pathway Biology
                  Performing detailed mechanistic analysis of biological signaling pathways, using quantitative approaches.
                   
                  Neurodegeneration and CNS Diseases
                  Expertise in CNS diseases such as Alzheimers, Parkinsons, Huntingtons Disease, Multiple Sclerosis, ALS, or others.
                   
                  Oncology
                  Expertise in disease biology and data analysis for cancer research.
                   
                  Computational Biology
                  Experience analyzing data (including gene expression, SNPs, exome and whole genome sequencing, RNA-Seq, and proteomic data), using computational methods to help facilitate the development of new medicines for patients with a variety of serious diseases.
                   
                  Next Generation Sequencing (NGS)
                  Expertise across the entire NGS pipeline including data QC, alignment and variant calling; pipeline implementation; and biological interpretation of the results. Experience applying approaches for CNV and structural variant / fusion detection. Ability to clearly communicate the process for each of these analyses, and weigh the applicability of differing tools and approaches.
                   
                  Machine Learning/Statistics (with Biological Applications)
                  Expertise in machine learning and statistical modeling with experience applying these approaches to biological data. Ability to develop and apply cutting-edge methods, and ability to clearly communicate the biological context and implications of the analyses to scientists with a range of expertise.
                   
                  Responsibilities
                  • Develop innovative algorithms and methods for analyzing data to identify biological insights
                  • Interpret data from a biological and clinical perspective
                  • Prepare next-generation sequencing (NGS) and other relevant genomic data for analysis
                  • Collaborate with colleagues to solve complex computational research problems
                  • Present scientific material (written and oral) to diverse audiences
                  Minimum Qualifications
                  • PhD in Computational Biology, Biostatistics or a related field (i.e., Biology, Engineering, Computer Science, Mathematics, Bioinformatics, Statistics) or 5+ years of work experience at a leading computational biology focused institution
                  • Demonstrated experience developing novel algorithms to address complex scientific problems
                  • Proven ability to work independently as well as contribute to larger initiatives
                  • Effective English communication skills (both written and oral)
                  • Proficient in at least one of R, Python, MATLAB, or a similar language.
                  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
                  • Experience applying machine learning approaches to analysis of heterogeneous biological data (for machine learning / statistical expert position only)
                  Preferred Qualifications (in addition to those noted in Minimum Qualifications section above)
                  • Postdoctoral experience in a top lab with computational biology and/or biostatistics experience
                  • Broad and deep understanding of genetics, proteomics, and/or genomics as documented by a strong publication record in high-impact journals
                  • Proficient in R
                  • Experience applying machine learning and statistical approaches to analysis of clinical and pre-clinical data (for machine learning / statistical expert position only)
                  For more information, please visit www.immuneering.com
                   
                  If interested and qualified, please email resume to careers@immuneering.com.  Please ensure to include the position title in the subject line.  We are seeking full-time candidates, but may have part-time consulting roles available under the right circumstances (please specify in your email message).

                   

                  IIE EU - U.S.  EDUCATION COOPERATION FOR RESEARCHERS

                  For information on EU – U.S. cooperation in doctoral and postdoctoral education opportunities for U.S. researchers and organizations.

                  Visit IIE online at www.iie.org.
                  Please contact the programs directly for additional information or with any questions you may have.
                   
                  A quote from a recent Fulbright U.S. student, "My advice to Fulbrighters of the future is that which was given to me. Go at it with an open mind; your experience will not be anything like you predicted and will mark you indelibly, but it will be great."

                   
                   

                  Career Programs

                   

                  PROPEL CAREERS - FUTURES IN LIFE SCIENCES (FILS) EVENTS FOR 2015

                  The FILS series is organized for current graduate students (MBA, MD, MPH, JD, Eng, Ph.D., MD etc), post doctoral fellows, medical resident, and early career professionals to learn about the variety of career paths that exist within the life sciences sector Together, Propel Careers, MassBio, and MassBioEd are committed to fostering the next generation of industry leaders in the life sciences.
                  Dates for the remainder of the 201 Series are listed below:
                  • October 20, 2015: Commercialization II (Reimbursement, Patient Advocacy,  Pharmacoeconomics, Market Access) Career Paths. Register here
                  • Nov 2015: Career Paths in Research & Development II (Preclinical Research, Clinical Biomarker Development, Research Operations/Finance, Project Management). Register here.                 
                   
                  MCKINSEY & COMPANY: WEB PRESENTATIONS AND 2016 FULL-TIME OPPORTUNITIES
                   
                  Did you know that McKinsey & Company, a global management consulting firm, has been hiring advanced professional degree (APD) candidates just like you for over 20 years?  Over half of our 9000 consultants in our 100+ offices worldwide hold PhD, MD, JD and non-MBA Masters degrees. 
                   
                  Please join McKinsey & Company via WebEx to learn about our work, our people and our exciting career opportunities for APD candidates, including our 2016 full-time opportunities for PhDs, Postdocs, non-MBA Masters, medical students, Interns, Residents and Fellows. 
                   
                  Web Presentations 
                  We are hosting web based presentations to help graduate students learn more about McKinsey & Company.  Please visit our “Online Events” section on our website for available dates and to RSVP:
                   
                  MD Fellowship 
                  We are excited to announce the McKinsey MD Fellowship, a learning program for medical students who seek to become proficient in the business of medicine.  The paid MD Fellowship offers medical students, between their third and fourth years, the opportunity to spend two years as a McKinsey consultant, working with healthcare leaders in the private, public, and social sectors.  Offered in most of our North America offices. Please visit our MD Fellow page to learn more about the program. Winter Interview Cycle: Early December application deadline with interviews taking place in January-February 2016
                   
                  Diversity & Inclusion at McKinsey 
                  At McKinsey, we are dedicated to building a great firm that attracts, develops, excites, and retains exceptional people.  We aspire to be recognized as the best professional services firm in the world for all candidates, regardless of race, gender identity, sexual orientation, or background.  To learn more about McKinsey Women, please follow us on Facebook @ McKinsey Women and view our electronic women's brochure.  To learn more about our other diversity networks, including Black Consultants at McKinsey, Hispanic and Latino Consultants at McKinsey, and LGBT colleagues at McKinsey, please visit the Diversity & Inclusion section of our website.
                   
                            

                  GRADUATE STUDENT CAREER EVENTS - WEBSITE & CALENDAR

                  For those who are looking for other resources, recordings of career related workshops and sessions for grad students available here: http://gecd.mit.edu/resources/workshops

                  The GECD Event calendar can be found here. 
                   
                   

                  GECD OFFERS THE VERSATILE PHD RESOURCE TOOL

                  Global Education & Career Development (GECD) is pleased to announce MIT’s subscription to The Versatile PhD, a web-based resource for PhDs considering careers beyond academia. Our subscription, generously supported by ODGE, can be accessed by students and alumni via GECD’s webpage and student CareerBridge accounts. Once students register, they can simply log in to the site directly (www.versatilephd.com) 
                   
                   

                  MIT CAREERBRIDGE

                  There are hundreds of jobs and internships now posted on CareerBridge, under both the Job Search and the On-Campus Interviews tabs. Check both tabs and apply as soon as possible.

                   

                  Follow HST on Twitter Follow mit_hst on Twitter

                   

                   

                  Prof. Emery Brown Faculty Talk Series “Getting from Here to There”

                  $
                  0
                  0

                  Want to know how MIT professors made their academic and career choices?

                  Come hear their stories at the new faculty talk series:

                  “Getting from Here to There”

                  Prof. Emery Brown will share his journey on becoming a renowned
                  neuroscientist, anesthesiologist, statistician, and MIT faculty member.

                  Wednesday, September 30, 2015 @ 5:15pm in 6-120

                  Sponsored by the Office of the Chancellor

                  http://chancellor.mit.edu/news/faculty-talks-getting-from-here-to-there

                  Date and Time: 
                  Wednesday, September 30, 2015 - 5:15pm
                  Location: 

                  6-120

                  Finding a Noninvasive Way to Measure Pressure in the Brain

                  $
                  0
                  0
                  Wednesday, September 30, 2015

                  Thomas Heldt. Photo by Lillie Paquette, School of Engineering

                  Current methods to check for increased pressure in a patient’s brain are invasive. One widely used technique is to drill a hole in the skull to insert a catheter or sensor into the brain tissue. Because of the risk of brain injury and infection, doctors typically only measure intracranial pressure — or ICP — when a patient is very sick, even though knowledge of this pressure could be useful in the diagnosis or treatment of a wider variety of conditions, such as malaria and unexplained headaches.

                  In an ongoing study announced today, researchers in MIT’s Institute for Medical Engineering and Science (IMES) have teamed up with surgeons at Boston Medical Center’s Department of Neurosurgery to test and refine a noninvasive way to measure intracranial pressure. The project, supported by a two-year grant from Philips, will put new ultrasound technology and algorithms into action to evaluate ICP in patients with traumatic brain injuries, strokes, brain tumors, hydrocephalus, and other conditions.

                  “The current invasive method of measuring ICP is used only in the sickest patients, but knowledge of ICP is potentially important in a much broader population,” says Thomas Heldt, the Hermann L.F. von Helmholtz Career Development Professor at MIT's IMES and assistant professor in MIT’s Department of Electrical Engineering and Computer Science (EECS), who is principal investigator of the study. “Our goal is to develop a noninvasive method of measuring ICP that could be used in treating a much wider range of conditions. This project gives us an exciting opportunity to test innovative hardware and modeling techniques at the bedside in real time."

                  Heldt’s group is refining an algorithm that estimates ICP based on two measurements that can be taken noninvasively with ultrasound imaging technology. The first measurement, arterial blood flow velocity, or how quickly blood is moving through a patient’s arteries in the brain, will be measured using a portable ultrasound device developed by Philips.

                  The second measurement is the arterial blood pressure waveform. It will be taken using a device being developed at MIT’s EECS by Charles Sodini, the Clarence J. LeBel Professor of Electrical Engineering, and Hae-Seung Lee, the Advanced Television and Signal Processing Professor of Electrical Engineering. Conventional blood pressure measurements capture only the peaks in pressure when the heart beats, and the lows between beats. Sodini and Lee’s device will measure tiny changes in arterial diameter, even between heartbeats, to capture the entire shape of the blood pressure waveform.

                  Over the next two years, Heldt and colleagues will collaborate with neurosurgeons at the Boston Medical Center, including principal investigator and chair of neurosurgery James Holsapple and co-investigator Aristotelis Filippidis, in two phases. First they will collect baseline data from patients in the Neuro Intensive Care Unit who have undergone the invasive method of measuring intracranial pressure. Then, they will test the new algorithm and technology to actually calculate patients’ ICP.

                  The method being developed is intended to be portable, allowing it to be used outside the hospital. For example, EMTs could bring the technology to the site of an accident to immediately assess whether a patient has a serious brain injury.

                  “Today it is very difficult to gauge the level of head trauma someone has sustained at the scene of an incident, because there is no quick and effective way to gauge the pressure inside the skull,” said Joseph Frassica, chief science officer of Philips Research North America. “Whether you’re a high school football player, in the NFL, or a soldier in the battlefield, or unfortunate enough to be injured in an auto accident — we hope that this technology will give first responders a better way to determine if you have a life-threatening brain injury and allow faster and more accurate triage and treatment.”

                  This work is supported by Philips Research as part of the MIT-Philips research alliance.

                  Audrey Resutek | Department of Electrial Engineering and Computer Science

                  http://news.mit.edu/2015/finding-noninvasive-way-to-measure-brain-pressure-0930

                  Viewing all 961 articles
                  Browse latest View live




                  Latest Images